interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development
EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
Clinical Trials Information System (CTIS).
The EU Clinical Trials Register currently displays
44358
clinical trials with a EudraCT protocol, of which
7384
are clinical trials conducted with subjects less than 18 years old.
The register also displays information on
18700
older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).
Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see
Frequently Asked Questions ).
Sponsor Name:Grupo Español de Investigación en Cancer de Ovario
Full Title: Multicentric Single Arm Phase II Clinical Trial, to Evaluate Safety and Efficacy of the Combination of Olaparib and PLD for Platinum Resistant Ovarian Primary Peritoneal Carcinoma, and Fallopian Tu...
Medical condition: Platinum resistant ovarian primary peritoneal carcinoma, and fallopian tube cancer patients.
Disease:
Version
SOC Term
Classification Code
Term
Level
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10070908
Ovarian cancer stage IV
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10057529
Ovarian cancer metastatic
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Sponsor Name:Bristol-Myers Squibb International Corporation
Full Title: A Phase 2 Open-label Randomized Study of Farletuzumab Ecteribulin (MORAb-202), a Folate Receptor Alpha-targeting Antibody-Drug Conjugate, versus Investigator’s Choice Chemotherapy in Women with Pla...
Medical condition: Platinum-resistant High-grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Disease:
Version
SOC Term
Classification Code
Term
Level
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10033128
Ovarian cancer
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10016180
Fallopian tube cancer
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10052171
Peritoneal carcinoma
LLT
Population Age: Adults, Elderly
Gender: Female
Trial protocol:ES(Ongoing)IT(Trial now transitioned)BE(Trial now transitioned)
Trial results:(No results available)
EudraCT Number: 2020-004936-72
Sponsor Protocol Number: WO42178
Start Date*: 2021-08-25
Sponsor Name:F. Hoffmann-La Roche Ltd
Full Title: A PHASE II, OPEN-LABEL, MULTICENTER, PLATFORM STUDY EVALUATING THE EFFICACY AND SAFETY OF BIOMARKER-DRIVEN THERAPIES IN PATIENTS WITH PERSISTENT OR RECURRENT RARE EPITHELIAL OVARIAN TUMORS
Medical condition: Persistent or Recurrent Rare Epithelial Ovarian Tumors
Disease:
Version
SOC Term
Classification Code
Term
Level
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10033128
Ovarian cancer
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10033129
Ovarian neoplasms malignant (excl germ cell)
HLT
21.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10066697
Ovarian cancer recurrent
PT
21.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10026669
Malignant peritoneal neoplasm NOS
LLT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10033159
Ovarian epithelial cancer NOS
LLT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10016180
Fallopian tube cancer
PT
Population Age: Adults, Elderly
Gender: Female
Trial protocol:FR(Trial now transitioned)CZ(Trial now transitioned)DE(Trial now transitioned)BE(Completed)IT(Trial now transitioned)
Full Title: A Randomized, Double-Blind, Placebo Controlled, Phase 2 Trial of Paclitaxel in Combination With AMG 386 in Subjects With Advanced Recurrent Epithelial Ovarian or Primary Peritoneal Cancer
Medical condition: Advanced Recurrent Epithelial Ovarian or Primary Peritoneal Cance
Disease:
Version
SOC Term
Classification Code
Term
Level
17.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Full Title: Randomized phase III trial on NIraparib-TSR-042 (dostarlimab) vs physician’s choice CHEmotherapy in recurrent, ovarian, fallopian tube or primary peritoneal cancer patients not candidate for platin...
Medical condition: Recurrent ovarian, fallopian tube or primary peritoneal cancer.
Disease:
Version
SOC Term
Classification Code
Term
Level
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10061344
Peritoneal neoplasm
PT
21.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10066697
Ovarian cancer recurrent
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10016180
Fallopian tube cancer
PT
Population Age: Adults, Elderly
Gender: Female
Trial protocol:IT(Trial now transitioned)DE(Trial now transitioned)FR(Trial now transitioned)CZ(Trial now transitioned)GR(Prematurely Ended)
Trial results:(No results available)
EudraCT Number: 2017-004557-17
Sponsor Protocol Number: CO-338-087
Start Date*: 2018-09-11
Sponsor Name:Clovis Oncology, Inc.
Full Title: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase 3 Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Pla...
Medical condition: advanced (FIGO stage III-IV), high-grade epithelial ovarian, fallopian tube, or primary peritoneal cancer (who responded to front-line platinum-based chemotherapy)
Disease:
Version
SOC Term
Classification Code
Term
Level
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10016180
Fallopian tube cancer
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10061328
Ovarian epithelial cancer
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10061269
Malignant peritoneal neoplasm
PT
Population Age: Adults, Elderly
Gender: Female
Trial protocol:GB(GB - no longer in EU/EEA)DE(Trial now transitioned)ES(Ongoing)BE(Trial now transitioned)FI(Completed)PL(Trial now transitioned)GR(Trial now transitioned)DK(Trial now transitioned)CZ(Trial now transitioned)IT(Trial now transitioned)RO(Trial now transitioned)
Trial results:(No results available)
EudraCT Number: 2020-004083-25
Sponsor Protocol Number: NOGGO-ov44
Start Date*: 2021-10-21
Sponsor Name:NOGGO e.V.
Full Title: Phase II investigational study of pembrolizumab combination with chemotherapy in platinum-sensitive recurrent low-grade serous ovarian cancer
Medical condition: platinum-sensitive recurrent low-grade serous ovarian cancer (including patients with primary peritoneal and / or fallopian tube adenocarcinoma)
Disease:
Version
SOC Term
Classification Code
Term
Level
21.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Full Title: A Phase III Randomised, Double Blind, Placebo Controlled, Multicentre Study of Olaparib Maintenance Monotherapy in Platinum Sensitive Relapsed BRCA Mutated Ovarian Cancer Patients who are in Comple...
Medical condition: BRCA Mutated Platinum Sensitive Relapse (PSR) high grade Serous Ovarian Cancer
Disease:
Version
SOC Term
Classification Code
Term
Level
19.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10014733
Endometrial cancer
PT
19.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10061269
Malignant peritoneal neoplasm
PT
19.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10016180
Fallopian tube cancer
PT
19.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10033128
Ovarian cancer
PT
Population Age: Adults, Elderly
Gender: Female
Trial protocol:GB(GB - no longer in EU/EEA)NL(Completed)IT(Completed)ES(Ongoing)FR(Ongoing)PL(Completed)DE(Completed)BE(Completed)
Trial results:(No results available)
EudraCT Number: 2011-005197-40
Sponsor Protocol Number: I1D-MC-JIAE
Start Date*: 2012-07-20
Sponsor Name:Eli Lilly and Company
Full Title: A Randomized, Double-Blind, Placebo-Controlled Phase 1b/2 Study of LY2228820, a p38MAPK Inhibitor, plus Gemcitabine and Carboplatin versus Gemcitabine and Carboplatin for Women with Platinum-Sensit...
Medical condition: Epithelial ovarian cancer, fallopian tube cancer, and primary peritoneal cancer
Disease:
Version
SOC Term
Classification Code
Term
Level
19.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Sponsor Name:Nordic Society of Gynaecological Oncology - Clinical Trial Unit
Full Title: Niraparib versus niraparib-bevacizumab combination in Women with platinum-sensitive epithelial ovarian, fallopian tube, or peritoneal cancer.
Part 1: AVANOVA1 - A phase I study to evaluate the saf...
Medical condition: Women with relapsed platinum-sensitive epithelial ovarian cancer
Disease:
Version
SOC Term
Classification Code
Term
Level
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10061328
Ovarian epithelial cancer
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10061344
Peritoneal neoplasm
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Sponsor Name:ISTITUTO NAZIONALE PER LO STUDIO E LA CURA DEI TUMORI - FONDAZIONE "G. PASCALE"
Full Title: A multicenter study in patients with stage III-IV epithelial ovarian cancer treated with carboplatin/paclitaxel with bevacizumab: clinical and biological prognostic factors
Medical condition: advanced ovarian cancer
Disease:
Version
SOC Term
Classification Code
Term
Level
15.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Full Title: A Randomized Phase III, Two-Arm Trial of Paclitaxel/Carboplatin/Maintenance Letrozole Versus Letrozole Monotherapy in Patients with Stage II-IV, Primary Low-Grade Serous Carcinoma of the Ovary or P...
Medical condition: Primary low-grade serous carcinoma of the ovary or peritoneum.
Disease:
Version
SOC Term
Classification Code
Term
Level
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10007107
Cancer of ovary
LLT
21.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Full Title: A Phase III Randomised, Double-Blind, Placebo-Controlled, Multicentre Study of Durvalumab in Combination with Chemotherapy and Bevacizumab, Followed by Maintenance Durvalumab, Bevacizumab and Olapa...
Medical condition: Newly diagnosed advanced (FIGO stage III-IV) high grade epithelial ovarian, fallopian or primary peritoneal cancer
Disease:
Version
SOC Term
Classification Code
Term
Level
27.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10070907
Ovarian cancer stage III
PT
27.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10070908
Ovarian cancer stage IV
PT
21.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10016186
Fallopian tube cancer stage III
PT
21.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10016187
Fallopian tube cancer stage IV
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10052171
Peritoneal carcinoma
LLT
Population Age: Adults, Elderly
Gender: Female
Trial protocol:DK(Trial now transitioned)DE(Trial now transitioned)FI(Trial now transitioned)HU(Trial now transitioned)ES(Ongoing)BE(Trial now transitioned)AT(Trial now transitioned)FR(Trial now transitioned)PL(Trial now transitioned)BG(Trial now transitioned)IT(Trial now transitioned)RO(Trial now transitioned)
Trial results:(No results available)
EudraCT Number: 2013-002520-17
Sponsor Protocol Number: GOGER-01
Start Date*: 2013-11-27
Sponsor Name:AOU di Bologna, Policlinico S.Orsola-Malpighi
Full Title: Randomized phase II study of 3 vs 6 courses of neoadjuvant carboplatin-paclitaxel chemotherapy in stage IIIC or IV epithelial ovarian cancer, fallopian tube carcinoma or primary peritoneal carcinoma
Medical condition: neoadjuvant carboplatin-paclitaxel chemotherapy in stage IIIC or IV epithelial ovarian cancer, fallopian tube carcinoma or primary peritoneal carcinoma
Disease:
Version
SOC Term
Classification Code
Term
Level
16.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10070908
Ovarian cancer stage IV
PT
16.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10070907
Ovarian cancer stage III
PT
16.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10016187
Fallopian tube cancer stage IV
PT
16.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10068974
Peritoneal carcinoma metastatic
PT
16.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Full Title: SORAYA: A Phase 3, Single Arm Study of Mirvetuximab Soravtansine in Platinum-Resistant, Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers with High Folate Recept...
Medical condition: Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers with High Folate Receptor-Alpha Expression
Disease:
Version
SOC Term
Classification Code
Term
Level
21.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10061269
Malignant peritoneal neoplasm
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10061328
Ovarian epithelial cancer
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Full Title: PICCOLO: A Phase 2, Single Arm Study of Mirvetuximab Soravtansine in Recurrent Platinum-Sensitive, High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers with High Folate Rece...
Medical condition: Recurrent Platinum-Sensitive, High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers with High Folate Receptor-Alpha Expression
Disease:
Version
SOC Term
Classification Code
Term
Level
21.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10061269
Malignant peritoneal neoplasm
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10061328
Ovarian epithelial cancer
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Full Title: A Phase 1/2a/3 Evaluation of the Safety and Efficacy of Adding AL3818 (Anlotinib, INN: Catequentinib), a Dual Receptor Tyrosine Kinase Inhibitor, to Standard Platinum-Based Chemotherapy in Subjects...
Medical condition: Recurrent or metastatic endometrial, ovarian, fallopian tube, primary peritoneal, or cervical carcinoma.
Disease:
Version
SOC Term
Classification Code
Term
Level
21.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10014734
Endometrial cancer metastatic
PT
21.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10014736
Endometrial cancer recurrent
PT
21.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10057529
Ovarian cancer metastatic
PT
21.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10066697
Ovarian cancer recurrent
PT
Population Age: Adults, Elderly
Gender: Female
Trial protocol:ES(Ongoing)IT(Trial now transitioned)
Trial results:(No results available)
EudraCT Number: 2010-024077-39
Sponsor Protocol Number: 55092
Start Date*: 2012-05-18
Sponsor Name:European Organisation for Research and Treatment of Cancer
Full Title: Phase IB-II, open label, multicentre feasibility study of pazopanib in combination with Paclitaxel and Carboplatin in patients with platinumrefractory/ resistant ovarian, fallopian tube or peritone...
Medical condition: Patients with platinum resistant ovarian, fallopian tube or peritoneal carcinoma.
Disease:
Version
SOC Term
Classification Code
Term
Level
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
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