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Clinical trials for Brain aneurysm

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    30 result(s) found for: Brain aneurysm. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2017-000514-35 Sponsor Protocol Number: Protect-U Start Date*: 2018-04-04
    Sponsor Name:Ruprecht-Karls-University Heidelberg, Medical Faculty Mannheim
    Full Title: Prospective Randomised Open-label Trial to Evaluate risk faCTor management in patients with Unruptured intracranial aneurysms (PROTECT-U)
    Medical condition: Saccular cerebral aneurysm
    Disease: Version SOC Term Classification Code Term Level
    20.1 10029205 - Nervous system disorders 10022758 Intracranial aneurysm PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned) FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-002008-15 Sponsor Protocol Number: NL65095.041.18 Start Date*: 2018-06-08
    Sponsor Name:University Medical Center Utrecht
    Full Title: Optimal cerebral perfusion after an extracranial-intracranial bypass: should we increase blood pressure or cardiac output?
    Medical condition: Patients with an indication for an extracranial-intracanial bypass (e.g. Moya Moya Disease, occluded carotid artery, giant aneurysm)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10029999 Occlusion carotid LLT
    20.1 100000004852 10002333 Aneurysm cerebral LLT
    20.1 100000004852 10002337 Aneurysm intracranial LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2016-004521-17 Sponsor Protocol Number: BIT-001 Start Date*: 2018-02-19
    Sponsor Name:BIT Pharma GmbH
    Full Title: A Phase IIa: single ascending dose safety, tolerability and pharmacokinetic study of NicaPlant® in aneurysmal subarachnoid haemorrhage patients undergoing aneurysm clipping
    Medical condition: Aneurysmal subarachnoid haemorrhage
    Disease: Version SOC Term Classification Code Term Level
    20.1 10029205 - Nervous system disorders 10008111 Cerebral haemorrhage PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2018-000241-39 Sponsor Protocol Number: ID-054-304 Start Date*: 2018-08-27
    Sponsor Name:Idorsia Pharmaceuticals Ltd
    Full Title: A prospective, multi-center, double-blind, randomized, placebo-controlled, parallel-group, Phase 3 study to assess the efficacy and safety of clazosentan in preventing clinical deterioration due to...
    Medical condition: Aneurysmal Subarachnoid Hemorrhage
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029205 - Nervous system disorders 10039330 Ruptured cerebral aneurysm PT
    21.1 10029205 - Nervous system disorders 10042316 Subarachnoid haemorrhage PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) DE (Completed) SE (Completed) FR (Completed) CZ (Completed) BE (Completed) DK (Completed) HU (Completed) AT (Completed) PL (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2022-003315-28 Sponsor Protocol Number: DR220153 Start Date*: 2023-02-15
    Sponsor Name:University of Calgary
    Full Title: Evaluating oral peri-operative acetylsalicylic acid in subjects undergoing endovascular coiling-only of unruptured brain aneurysms
    Medical condition: Subjects undergoing elective endovascular coiling-only (primary or balloon-assisted) repair of unruptured brain aneurysms.
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004852 10002334 Aneurysm cerebral (unruptured) LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-000790-79 Sponsor Protocol Number: 2018-000790-79 Start Date*: 2021-08-09
    Sponsor Name:Academic Medical Centre Amsterdam
    Full Title: IMPROVING OUTCOME IN SUBARACHNOID HEMORRHAGE WITH NADROPARINE
    Medical condition: Patients suffering from an aneurysmal subarachnoid hemorrhage.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-005033-53 Sponsor Protocol Number: EG-01-1962-03 Start Date*: 2017-02-01
    Sponsor Name:Edge Therapeutics, Inc
    Full Title: Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Efficacy and Safety Study Comparing EG-1962 to Standard of Care Oral Nimodipine in Adults with Aneurysmal Subarac...
    Medical condition: Aneurysmal subarachnoid hemorrhage (aSAH)
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10072200 Asymptomatic subarachnoid hemorrhage LLT
    20.1 100000004863 10042320 Subarachnoid hemorrhage LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) CZ (Completed) FI (Prematurely Ended) DK (Prematurely Ended) AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-003716-12 Sponsor Protocol Number: RHNIA-001-2021 Start Date*: 2022-08-24
    Sponsor Name:Rigshospitalet
    Full Title: S-ketamine for cortical spreading depolarisation in patients with severe acute brain injury
    Medical condition: Severe acute brain injury caused by aneurysmal subarachnoid hemorrhage, spontaneous intracerebral hemorrhage or traumatic brain injury.
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10018061 General anesthesia LLT
    21.1 100000004865 10070731 Electrocorticography LLT
    20.0 100000004852 10056389 Brain damage LLT
    21.0 100000004852 10019529 Hemorrhage brain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2010-023878-40 Sponsor Protocol Number: 2.3 Start Date*: 2011-12-22
    Sponsor Name:Medical University Vienna
    Full Title: Influence of intra-arterial cerebral Papaverine Hydrochloride on cerebral glucose, lactate, pyruvate, glycerol, and glutamate concentrations, cerebral oxygenation, angiographic vasospasm, delayed s...
    Medical condition: To demonstrate the influence of intra-arterial cerebral Papaverine Hydrochloride on cerebral glucose, lactate, pyruvate, glycerol, and glutamate concentrations and cerebral oxygenation in patients ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2019-001542-17 Sponsor Protocol Number: T109/2019Xe-SAH Start Date*: 2020-09-17
    Sponsor Name:Timo Laitio
    Full Title: Effect of xenon on brain injury, neurological outcome and survival in patients after aneurysmal subarachnoid hemorrhage
    Medical condition: Acute rupture of cerebral aneurysm, subarachnoid hemorrhage (SAH), unconsciousness, brain injury.
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004852 10008078 Cerebral arterial aneurysm LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2012-000068-11 Sponsor Protocol Number: SAVDEX-12 Start Date*: 2012-05-16
    Sponsor Name:Turku University Hospital
    Full Title: The effects of dexmedetomidine on cerebral autoregulation and cerebral oxygenation in subarachnoid haemorrhage patients.
    Medical condition: This study will be conducted on aneurysmal subarachnoid hemorrhage patients.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002457-30 Sponsor Protocol Number: 13.0099 Start Date*: 2013-09-13
    Sponsor Name:St George's University of London
    Full Title: An open label randomised controlled trial investigating the effect of donepezil on regional cerebral blood flow in adults with aneurysmal subarachnoid haemorrhage.
    Medical condition: Aneurysmal subarachnoid haemorrhage Cerebral vasospasm Ischaemic stroke
    Disease: Version SOC Term Classification Code Term Level
    16.0 10029205 - Nervous system disorders 10047164 Vasospasm cerebral LLT
    16.0 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    16.0 10029205 - Nervous system disorders 10055845 Haemorrhage subarachnoid LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-000277-30 Sponsor Protocol Number: STASH01 Start Date*: 2006-07-06
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust [...]
    1. Cambridge University Hospitals NHS Foundation Trust
    2. Cambridge University
    Full Title: Simvastatin in aneurysmal subarchnoid haemorrhage (STASH): a multicentre randomised controlled clinical phase III study
    Medical condition: subarachnoid haemorrhage
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10019016 Haemorrhagic stroke PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) SE (Completed)
    Trial results: View results
    EudraCT Number: 2016-004739-19 Sponsor Protocol Number: OSU6162aSAH Start Date*: 2017-06-16
    Sponsor Name:Oslo University Hospital
    Full Title: OSU6162 IN THE TREATMENT OF FATIGUE AND OTHER NEUROPSYCHOLOGICAL SEQUELAE AFTER ANEURYSMAL SUBARACHNOIDAL HEMORRHAGE - A DOUBLE-BLIND, RANDOMISED, PLACEBO-CONTROLLED STUDY
    Medical condition: Fatigue and neuropsychological dysfunction after aneurysmal brain hemorrhage
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: View results
    EudraCT Number: 2017-000868-15 Sponsor Protocol Number: P001151 Start Date*: 2019-01-15
    Sponsor Name:Medical Center -University of Freiburg
    Full Title: Stereotactic Cisternal Lavage in Patients with Aneurysmal Subarachnoid Hemorrhage with Urokinase and Nimodipine for the Prevention of Secondary Brain Injury. A Randomized Controlled Trial.
    Medical condition: Aneurysmal Subarachnoid Hemorrhage (aSAH)
    Disease: Version SOC Term Classification Code Term Level
    20.1 10029205 - Nervous system disorders 10042320 Subarachnoid hemorrhage LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-000586-33 Sponsor Protocol Number: 19-PP-15 Start Date*: 2021-07-21
    Sponsor Name:CHU de Nice
    Full Title: Effect of molar sodium lactate infusion on cerebral hemodynamic in patients with severe subarachnoid hemorrhage: a multicenter double-blind randomized controlled study
    Medical condition: Subarachnoid hemorrhage caused by rupture of cerebral aneurysm
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004852 10042320 Subarachnoid hemorrhage LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-002721-18 Sponsor Protocol Number: AC-054-203 Start Date*: 2016-02-17
    Sponsor Name:Actelion Pharmaceuticals Ltd
    Full Title: A prospective, multi-center, open-label, single-arm, Phase 2 study to assess the efficacy and safety of clazosentan in reversing angiographically-confirmed cerebral vasospasm in adult subjects with...
    Medical condition: Aneurysmal subarachnoid hemorrhage (aSAH); cerebral vasospasm
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004852 10047164 Vasospasm cerebral LLT
    19.1 100000004863 10042320 Subarachnoid hemorrhage LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-002798-50 Sponsor Protocol Number: prostacyclin Start Date*: 2011-09-27
    Sponsor Name:Rune Rasmussen
    Full Title: Effect of prostacyclin infusion on cerebral vessels and metabolism in patients with subarachnoid haemorrhage
    Medical condition: Vasospasm following subarachnoid hemorrhage
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029205 - Nervous system disorders 10042320 Subarachnoid hemorrhage LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003200-23 Sponsor Protocol Number: 2013DR3084 Start Date*: 2016-04-21
    Sponsor Name:University Hospital Basel; Neurology
    Full Title: Biomarkers and antithrombotic treatment in cervical artery dissection (TREAT-CAD)
    Medical condition: cervical artery dissection
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2012-003190-26 Sponsor Protocol Number: RESTART13 Start Date*: 2013-01-14
    Sponsor Name:ACCORD (Academic and Clinical Central Office for Research & Development) [...]
    1. ACCORD (Academic and Clinical Central Office for Research & Development)
    2. ACCORD (Academic and Clinical Central Office for Research & Development)
    Full Title: REstart or STop Antithrombotics Randomised Trial (RESTART)
    Medical condition: Spontaneous Intracerebral Haemorrhage (ICH)
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004852 10022753 Intracerebral haemorrhage LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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