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Clinical trials for Hepatic coma

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    24 result(s) found for: Hepatic coma. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2008-005560-13 Sponsor Protocol Number: Hep-Net-HIDIT-2 Start Date*: 2009-06-12
    Sponsor Name:Medizinische Hochschule Hannover
    Full Title: A multicenter randomised study comparing the efficacy of pegylated interferon-alfa-2a plus placebo vs. pegylated interfeorn-alfa-2a plus tenofovir for the treatment of chronic delta hepatitis- The ...
    Medical condition: To compare the virological efficacy (HDV-RNA) and safety of 96 weeks of therapy with pegylated interferon-alfa-2a plus tenovofir to 96 weeks of therapy with pegylated interferon-alfa-2a plus placeb...
    Disease: Version SOC Term Classification Code Term Level
    15.1 100000004862 10047455 Viral hepatitis B without mention of hepatic coma, with hepatitis delta LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2018-002251-14 Sponsor Protocol Number: KCHATTIC01 Start Date*: 2019-01-02
    Sponsor Name:Kings College Hospital NHS Foundation Trust
    Full Title: Localized on site testing and treatment of hepatitis C in homeless persons in London: a pilot non-randomised phase 4 interventional clinical trial of grazoprevir and elbasvir ± ribavirin in partici...
    Medical condition: hepatitis C viral infection
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10008914 Chronic hepatitis C without mention of hepatic coma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-000931-20 Sponsor Protocol Number: TIPS-EE Start Date*: 2012-05-25
    Sponsor Name:AZIENDA UNIVERSITARIA POLICLINICO UMBERTO I DI ROMA
    Full Title: EFFECT OF ALBUMIN INFUSION TO PREVENT OVERT HEPATIC ENCEPHALOPATHY AFTER TRANSGIUGULAR INTRAHEPATIC PORTOSYSTEMIC SHUNT (TIPS).
    Medical condition: PREVENTION OF HEPATIC ENCEPHALOPATHY IN CIRRHOTIC PATIENTS WHO UNDERGO TIPS PLACEMENT
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10019660 Hepatic encephalopathy PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-000563-81 Sponsor Protocol Number: EME Start Date*: 2014-07-29
    Sponsor Name:FUNDACION PUBLICA ANDALUZA PARA LA GESTION DE LA INVESTIGACION EN SALUD DE SEVILLA
    Full Title: Metformin treatment of minimal hepatic encephalopathy in patients with liver cirrhosis
    Medical condition: minimal hepatic encephalopathy in patients with liver cirrhosis
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004852 10014630 Encephalopathy hepatic LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000706-36 Sponsor Protocol Number: P05498 Start Date*: 2008-09-30
    Sponsor Name:Hannover Medical School; Competence Network Viral Hepatitis (Hep-Net)
    Full Title: Optimization of treatment for patients with chronic hepatitis C infected with HCV-genotype 2 or 3: 12 vs. 24 weeks of treatment extension for patients without rapid virological response
    Medical condition: chronic hepatitis c infection genotype 2/3
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004862 10008914 Chronic hepatitis C without mention of hepatic coma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-005412-10 Sponsor Protocol Number: OCR002-HE209 Start Date*: 2014-08-25
    Sponsor Name:Ocera Therapeutics Inc
    Full Title: Multicenter, Randomized Phase 2B Study to Evaluate the Efficacy, Safety and Tolerability of OCR-002 (ornithine phenylacetate) in Hospitalized Patients with Cirrhosis and Associated Hyperammonemi...
    Medical condition: Hepatic encephalopathy
    Disease: Version SOC Term Classification Code Term Level
    18.0 10029205 - Nervous system disorders 10019660 Hepatic encephalopathy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: EE (Completed) CZ (Completed) AT (Completed) HU (Completed) IT (Completed) DE (Completed) NL (Completed) BE (Completed) DK (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2014-004809-33 Sponsor Protocol Number: BETA Start Date*: 2015-03-09
    Sponsor Name:Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca (VHIR)
    Full Title: Albumin infusion effects in patients with cirrhosis hepatic encephalopathy
    Medical condition: hepatic encephalopathty
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004871 10019642 Hepatic cirrhosis NOS LLT
    17.1 10029205 - Nervous system disorders 10019660 Hepatic encephalopathy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2022-001993-78 Sponsor Protocol Number: VIR-CHDV-V201 Start Date*: 2023-01-05
    Sponsor Name:Vir Biotechnology, Inc.
    Full Title: A Phase 2 Study to Evaluate Efficacy, Safety and Tolerability of VIR-2218 and VIR-3434 in Participants with Chronic Hepatitis D Virus Infection (SOLSTICE)
    Medical condition: Chronic Hepatitis D Virus (HDV) Infection
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10019762 Hepatitis D PT
    20.0 10021881 - Infections and infestations 10047455 Viral hepatitis B without mention of hepatic coma, with hepatitis delta LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Trial now transitioned) NL (Trial now transitioned) DE (Trial now transitioned) IT (Trial now transitioned) RO (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-002924-11 Sponsor Protocol Number: LOLAbiome Start Date*: 2023-01-09
    Sponsor Name:CBmed GmbH
    Full Title: An observational study on the effect of L-ornithine-L-aspertate (LOLA) on the Flavonifractor abundance in the gut microbiome in liver cirrhosis
    Medical condition: Liver cirrhosis with covert or overt hepatic encephalopathy (grade 0-2)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004871 10024667 Liver cirrhosis LLT
    20.0 100000004852 10014630 Encephalopathy hepatic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-003817-32 Sponsor Protocol Number: LOLA-Merz:WMDHP39937 Start Date*: 2013-01-08
    Sponsor Name:Imperial College London
    Full Title: Brain muscle axis during treatment of hepatic encephalopathy with L-ornithine L-aspartate
    Medical condition: Hepatic Encephalopathy
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10019660 Hepatic encephalopathy PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-004708-20 Sponsor Protocol Number: RIFSYS Start Date*: 2014-03-27
    Sponsor Name:King's College London [...]
    1. King's College London
    2. King's College Hospital NHS Foundation Trust
    Full Title: A placebo controlled single centre double blind randomised trial to investigate the efficacy of rifaximin versus placebo in improving systemic inflammation and neutrophil malfunction in patients wi...
    Medical condition: Cirrhosis and chronic hepatic encephalopathy
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004871 10024667 Liver cirrhosis LLT
    18.0 10029205 - Nervous system disorders 10019660 Hepatic encephalopathy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-003376-21 Sponsor Protocol Number: ALFAE Start Date*: 2008-11-14
    Sponsor Name:Servicio Hepatología. Hospital Vall d'Hebron
    Full Title: EFECTOS DE LA ADMINISTRACIÓN DE ALBÚMINA EN PACIENTES CON CIRROSIS Y ENCEFALOPATIA HEPÁTICA AGUDA
    Medical condition: Encefalopatía hepática en pacientes con cirrosis hepática.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019660 Hepatic encephalopathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2005-000837-39 Sponsor Protocol Number: CCD01 Start Date*: 2007-08-15
    Sponsor Name:Cytonet GmbH & Co. KG
    Full Title: Open, randomized, prospective, controlled, multicentre study to evaluate the efficacy and safety of multiple intraportal applications of liver cell suspension in patients with acute liver failure n...
    Medical condition: Acute Liver Failure Subgroups of patients with indications falling under ICD classification codes:K70.4, K71, K72, K75, K76, K77
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049844 Acute liver failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) GB (Prematurely Ended) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-005969-13 Sponsor Protocol Number: AXA1665-101 Start Date*: 2021-08-11
    Sponsor Name:Axcella Health, Inc.
    Full Title: A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of AXA1665 in Subjects With Liver Cirrhosis and Prior Overt Hepatic Encephalopathy (EM...
    Medical condition: Overt Hepatic Encephalopathy in Subjects with Liver Cirrhosis
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029205 - Nervous system disorders 10019660 Hepatic encephalopathy PT
    20.0 100000004871 10024667 Liver cirrhosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) PL (Completed) HU (Prematurely Ended) IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-004323-37 Sponsor Protocol Number: PEARL-trial Start Date*: 2019-06-06
    Sponsor Name:Academic Medical Centre
    Full Title: Prevention of hepatic Encephalopathy by Administration of Rifaximin and Lactulose in patients with liver cirrhosis undergoing placement of a transjugular intrahepatic portosystemic shunt: a multi-c...
    Medical condition: post-TIPS Hepatic Encephalopathy (HE)
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029205 - Nervous system disorders 10019660 Hepatic encephalopathy PT
    20.0 10029205 - Nervous system disorders 10076204 Minimal hepatic encephalopathy PT
    20.1 10042613 - Surgical and medical procedures 10066599 Hepatic encephalopathy prophylaxis PT
    21.1 10042613 - Surgical and medical procedures 10068826 Transjugular intrahepatic portosystemic shunt LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned) BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2019-005008-16 Sponsor Protocol Number: STOPPIT-01 Start Date*: 2021-03-08
    Sponsor Name:University Medical Center Hamburg-Eppendorf
    Full Title: Stop of proton-pump inhibitor treatment in patients with liver cirrhosis – a double-blind, placebo-controlled trial
    Medical condition: Liver cirrhosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10019805 - Hepatobiliary disorders 10019641 Hepatic cirrhosis PT
    20.0 10019805 - Hepatobiliary disorders 10024667 Liver cirrhosis LLT
    20.0 10017947 - Gastrointestinal disorders 10003445 Ascites PT
    20.1 10021881 - Infections and infestations 10051156 Ascites infection LLT
    20.0 10021881 - Infections and infestations 10068547 Bacterascites PT
    20.0 10021881 - Infections and infestations 10068555 Monomicrobial non-neutrocytic bacterascites LLT
    24.1 10021881 - Infections and infestations 10061135 Spontaneous bacterial peritonitis PT
    21.1 10029205 - Nervous system disorders 10019660 Hepatic encephalopathy PT
    20.0 100000004866 10036201 Portal hypertensions HLT
    20.1 10019805 - Hepatobiliary disorders 10036200 Portal hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-003942-35 Sponsor Protocol Number: APHP200018 Start Date*: 2021-04-27
    Sponsor Name:Assistance Publique - Hôpitaux Paris
    Full Title: HydrOcortisone and fludRocortisoNe for critical ILLness-related corticosteroid insufficiency
    Medical condition: Critically ill patients with a SOFA score (SOFA; Sequential Organ Failure Assessment) ≥ 6, for at least 6 consecutive hours, suffering from CIRCI, to the notable exception of patients with septic s...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10018065 - General disorders and administration site conditions 10077264 Critical illness PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-004944-23 Sponsor Protocol Number: WFTL001 Start Date*: 2012-03-01
    Sponsor Name:Charité Universitätsmedizin
    Full Title:
    Medical condition: graft function adapted tacrolimus therapy after liver transplantation
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10024716 Liver transplantation LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-000823-15 Sponsor Protocol Number: NEUPRODEX Start Date*: 2013-12-23
    Sponsor Name:Charité – Universitätsmedizin Berlin
    Full Title: Neuroprotection with Dexmedetomidine in patients undergoing elective cardiac or abdominal surgery
    Medical condition: The drug Dexmedetomidine will be investigated in patients (men and women) undergoing elective cardiac or abdominal surgery. The study medication will be administered perioperatively by intravenous ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-001319-71 Sponsor Protocol Number: F1K-MC-EVBQ Start Date*: 2004-08-13
    Sponsor Name:Lilly S.A.
    Full Title: A Phase IIIb Study to Determine Efficacy and Safety of Extended Drotrecogin Alfa (Activated) Therapy in Patients With Persistent Requirement for Vasopressor Support After 96-Hour Infusion With Comm...
    Medical condition: in severe sepsis patients with persistent vasopressordependent hypotension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
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