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Clinical trials for bacterial infections and sepsis

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43845   clinical trials with a EudraCT protocol, of which   7282   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    179 result(s) found for: bacterial infections and sepsis. Displaying page 1 of 9.
    1  2  3  4  5  6  7  8  9  Next»
    EudraCT Number: 2011-005902-30 Sponsor Protocol Number: FAR01-2011 Start Date*: 2012-02-13
    Sponsor Name:Servicio de Farmacia. Hospital Universitari de Bellvitge
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10040047 Sepsis PT
    14.1 10021881 - Infections and infestations 10053840 Bacterial sepsis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-002788-28 Sponsor Protocol Number: RHM CHI434 Start Date*: 2008-01-15
    Sponsor Name:Southampton University Hospital NHS Trust
    Full Title: Evaluation of Corticosteroid therapy in Childhood Severe Sepsis (Steroids in Paediatric Sepsis, StePS) - a randomised pilot study
    Medical condition: Children with severe sepsis requiring mechanical ventilation presenting within 12 hours of onset. The majority of children will either have community acquired sepsis (most commonly meningococcal or...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10040047 Sepsis LLT
    9.1 10053840 Bacterial sepsis LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-000717-24 Sponsor Protocol Number: 230390 Start Date*: 2017-08-24
    Sponsor Name:Aarhus University Hospital
    Full Title: Concentration of piperacillin in plasma and subcutis in patients on crrt treatment
    Medical condition: infections reloated to CRRT
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000019640 10021804 Infection bacterial LLT
    20.0 100000015677 10021863 Infection respiratory LLT
    20.0 100000165071 10021867 Infection systemic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002926-35 Sponsor Protocol Number: 080716CT Start Date*: 2017-01-16
    Sponsor Name:Alder Hey Children's Foundation NHS Trust
    Full Title: Pharmacokinetics of post-operative Cefuroxime in infants undergoing cardiac surgery
    Medical condition: post operative paediatric cardiac patients
    Disease: Version SOC Term Classification Code Term Level
    19.1 10021881 - Infections and infestations 10053840 Bacterial sepsis PT
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2009-011346-26 Sponsor Protocol Number: MAB-N007 Start Date*: 2009-11-27
    Sponsor Name:Biosynexus Incorporated
    Full Title: Ensayo de fase 2b/3, multicéntrico, aleatorizado, doble ciego, controlado con placebo, para evaluar la seguridad y eficacia de Pagibaximab Inyectable en recién nacidos con peso de nacimiento muy ba...
    Medical condition: Prevención de la septicemia causada por estafilococos en recién nacidos con peso de nacimiento muy bajo.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10040049 Sepsis neonatal LLT
    12.0 10056430 Staphylococcal sepsis LLT
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: ES (Completed) GB (Completed) DE (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-001019-95 Sponsor Protocol Number: COLIMICINA Start Date*: 2021-05-31
    Sponsor Name:FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS UNIVERSITA' CATTOLICA DEL SACRO CUORE
    Full Title: Pharmacokinetic/pharmacodynamic aspects of colistin intravenous administration in critically ill patients suffering from hospital infections caused by multi-antibiotic-resistant germs and receiving...
    Medical condition: Critically ill patients suffering from hospital infections caused by multi-antibiotic-resistant germs and receiving continuous renal replacement therapy.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10053840 Bacterial sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001056-55 Sponsor Protocol Number: INCLASS Start Date*: 2017-08-28
    Sponsor Name:HELLENIC INSTITUTE FOR THE STUDY OF SEPSIS
    Full Title: A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED CLINICAL STUDY OF THE EFFICACY OF INTRAVENOUS CLARITHROMYCIN AS ADJUNCTIVE TREATMENT IN PATIENTS WITH SEPSIS AND RESPIRATORY AND MULTIPLE ORGAN DYSFUN...
    Medical condition: IMMUNE MODULATION WITH CLARITHROMYCIN IN SEPSIS WITH MULTIPLE ORGAN AND RESPIRATORY DYSFUNCTION
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Ongoing) BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-003698-13 Sponsor Protocol Number: ABR-54775 Start Date*: 2015-12-30
    Sponsor Name:Radboudumc
    Full Title: Neuroinflammation in sepsis encephalopathy: the NINEVEH-study
    Medical condition: sepsis
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004862 10040054 Sepsis, bacteraemia, viraemia and fungaemia NEC HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-002555-26 Sponsor Protocol Number: RH-RBWH-2014-1 Start Date*: 2014-07-25
    Sponsor Name:Dept. of Intensive Care Medicine, Copenhagen University Hospital, Rigshospitalet
    Full Title: MEROPENEM and CIPROFLOXACIN DOSING IN THE CRITICALLY ILL PATIENT WITH SEPTIC SHOCK – A SINGLE CENTER PHARMACOKINETIC STUDY
    Medical condition: Septic Shock
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004862 10040050 Sepsis NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2020-005768-74 Sponsor Protocol Number: ImmunoSep Start Date*: 2021-02-18
    Sponsor Name:Hellenic Institute for the Study of Sepsis
    Full Title: PERSONALIZED IMMUNOTHERAPY IN SEPSIS: A MULTICENTRE AND MULTINATIONAL, DOUBLE-BLIND, DOUBLE-DUMMY RANDOMIZED CLINICAL TRIAL (THE IMMUNOSEP TRIAL)
    Medical condition: Sepsis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10040053 Sepsis secondary LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Ongoing) NL (Ongoing) IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004333-42 Sponsor Protocol Number: SISPCT Start Date*: Information not available in EudraCT
    Sponsor Name:Friedrich-Schiller-University of Jena
    Full Title: Prospective randomized clinical multicenter trial about the effect of an adjunctive intravenous treatment with sodium selenite (selenase®T, double-blind) and a procalcitonin guided causal therapy (...
    Medical condition: severe sepsis / septic shock
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-002251-42 Sponsor Protocol Number: 3-001 Start Date*: 2012-11-05
    Sponsor Name: Asahi Kasei Pharma America Corporation
    Full Title: A RANDOMIZED, DOUBLE BLIND, PLACEBO–CONTROLLED, PHASE 3 STUDY TO ASSESS THE SAFETY AND EFFICACY OF ART-123 IN SUBJECTS WITH SEVERE SEPSIS AND COAGULOPATHY
    Medical condition: severe sepsis and coagulopathy
    Disease: Version SOC Term Classification Code Term Level
    18.1 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) NL (Completed) HU (Completed) FI (Completed) CZ (Completed) ES (Completed) BG (Prematurely Ended) GB (Completed) DE (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2017-002171-26 Sponsor Protocol Number: PROVIDE Start Date*: 2017-10-20
    Sponsor Name:Hellenic Institute for the Study of Sepsis
    Full Title: A PERSONALIZED RANDOMIZED TRIAL OF VALIdATION AND RESTORATION OF IMMUNE DYSFUNCTION IN SEVERE INFECTIONS AND SEPSIS: THE PROVIDE TRIAL
    Medical condition: A TRIAL FOR IMMUNOMODULATION IN SEPSIS
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-000902-37 Sponsor Protocol Number: RH-ITA-005 Start Date*: 2014-06-27
    Sponsor Name:Dept. of Intensive Care, Copenhagen University Hospital, Rigshospitalet
    Full Title: Conservative vs. Liberal Approach to fluid therapy of Septic Shock in Intensive Care
    Medical condition: Septic shock
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004862 10040050 Sepsis NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2011-004834-32 Sponsor Protocol Number: PROTEINA-C Start Date*: 2012-06-08
    Sponsor Name:FONDAZIONE CENTRO S. RAFFAELE DEL MONTE TABOR
    Full Title: Administration of concentrated Protein C in patients with severe sepsis and contraindications to activated protein C. A monocentric, randomised placebo-controlled study.
    Medical condition: patients affected by severe sepsis admitted to intensive care
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-015168-32 Sponsor Protocol Number: D0620C00003 Start Date*: 2010-10-04
    Sponsor Name:AstraZeneca AB
    Full Title: A Multicentre, Randomised, Double Blind, Placebo controlled Phase IIb Study to compare the Efficacy and Safety of Two Dosing Regimens of Intravenous Infusions of CytoFab™ (AZD9773) in Adult Patient...
    Medical condition: Severe sepsis and/or septic shock
    Disease: Version SOC Term Classification Code Term Level
    12.1 10040047 Sepsis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) FR (Completed) ES (Completed) CZ (Completed) FI (Completed)
    Trial results: View results
    EudraCT Number: 2014-002840-42 Sponsor Protocol Number: 3/035/14 Start Date*: 2014-12-15
    Sponsor Name:University of Aberdeen [...]
    1. University of Aberdeen
    2. NHS Grampian
    Full Title: Dose assessment of melatonin in sepsis trial (DAMSEL 2)
    Medical condition: Sepsis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10053879 Sepsis syndrome PT
    Population Age: Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2017-002011-33 Sponsor Protocol Number: PROGRESS Start Date*: 2017-08-28
    Sponsor Name:Hellenic Institute for the Study of Sepsis
    Full Title: A RANDOMIZED PROSPECTIVE CLINICAL TRIAL TO ASSESS THE ROLE OF PROCALCITONIN-GUIDED ANTIMICROBIAL THERAPY TO REDUCE LONG-TERM INFECTIONS SEQUELAE
    Medical condition: USE OF PROCALCITONIN IN EARLY STOP OF ANTIBIOTICS TO AVOID LONG-TERM CONSEQUENCES
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: View results
    EudraCT Number: 2018-001008-13 Sponsor Protocol Number: SUPERIOR Start Date*: 2018-07-09
    Sponsor Name:HELLENIC INSTITUTE FOR THE STUDY OF SEPSIS
    Full Title: A SUPAR GUIDED DOUBLE BLIND RANDOMIZED CLINICAL TRIAL OF INITIATION OF ANTIBIOTICS FOR PRESUMED INFECTION AT THE EMERGENCY DEPARTMENT: THE SUPERIOR TRIAL
    Medical condition: Α suPAR guided early antibiotic administration at the Emergency Room for presumed infection and sepsis and evaluation of the impact of this intervention to the patients’ final outcome
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-004239-29 Sponsor Protocol Number: E2011OBINFECTION Start Date*: 2011-10-04
    Sponsor Name:Hopital Erasme
    Full Title: what are the optimal doses of broad spectrum B-lactams to administer to obese patients if infected?
    Medical condition: any patient with a BMI >= 30kg/m² and has a simple or severe infection.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10021881 - Infections and infestations 10060945 Bacterial infection PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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