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Clinical trials for Ischemic Stroke

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44393   clinical trials with a EudraCT protocol, of which   7405   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    499 result(s) found for: Ischemic Stroke. Displaying page 9 of 25.
    EudraCT Number: 2010-019014-25 Sponsor Protocol Number: Istrokepilot Start Date*: 2010-07-27
    Sponsor Name:Karolinska University Hospital
    Full Title: A PROSPECTIVE, RANDOMISED, OPEN, BLINDED EVALUATION, ASCENDING-DOSE, PILOT TRIAL OF IMATINIB IN ACUTE ISCHAEMIC STROKE (I-STROKE/pilot)
    Medical condition: Acute ischaemic stroke
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005254-24 Sponsor Protocol Number: HA009 Start Date*: 2008-01-14
    Sponsor Name:Nuvelo, Inc
    Full Title: PHASE 2, MULTICENTER, OPEN-LABEL, TWO-STAGE STUDY TO EVALUATE THE SAFETY AND EFFICACY OF INTRA-ARTERIAL CATHETER-DIRECTED ALFIMEPRASE FOR RESTORATION OF NEUROLOGIC FUNCTION AND RAPID OPENING OF ART...
    Medical condition: Acute Ischemic Stroke (AIS)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10055221 Ischemic stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-000236-34 Sponsor Protocol Number: ELAN Start Date*: 2019-02-26
    Sponsor Name:Inselspital (University Hospital) Bern
    Full Title: Early versus Late initiation of direct oral Anticoagulants in post-ischaemic stroke patients with atrial fibrillatioN (ELAN): an international, multicentre, randomised-controlled, two-arm, assessor...
    Medical condition: Recurrent strokes in patients with atrial fibrillation who suffered an ischaemic stroke
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) FI (Completed) BE (Completed) DE (Completed) SK (Completed) PT (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2011-004616-36 Sponsor Protocol Number: D5135C00001 Start Date*: 2013-02-04
    Sponsor Name:AstraZeneca AB
    Full Title: A randomized, double-blind, parallel group, multicentre phase IIIb study to compare ticagrelor with clopidogrel treatment on the risk of cardiovascular death, myocardial infarction and ischemic str...
    Medical condition: peripheral artery disease
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004866 10067825 Peripheral arterial disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed) NL (Completed) PL (Completed) GB (Completed) SE (Completed) ES (Completed) DE (Completed) HU (Completed) BG (Completed) CZ (Completed) IT (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2006-003622-29 Sponsor Protocol Number: BAYe4465/IMPACT12198 Start Date*: 2007-06-13
    Sponsor Name:Bayer AG
    Full Title: The ARRIVE Study (Aspirin to Reduce Risk of Initial Vascular Events) - A Randomized, Double-Blind, Placebo Controlled, Multicenter, Parallel Group Study to Assess the Efficacy (Reduction of Cardiov...
    Medical condition: Patients at moderate risk of CHD events (10-20% 10-year CHD risk; approximately 30% 10-year risk of CVD events based on the underlying assumption at study start).
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004852 10072760 Transient ischemic attack LLT
    19.0 100000004852 10042244 Stroke LLT
    19.0 10007541 - Cardiac disorders 10046251 Unstable angina LLT
    19.0 10007541 - Cardiac disorders 10028596 Myocardial infarction PT
    19.0 10018065 - General disorders and administration site conditions 10049993 Cardiac death PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed) DE (Completed) IE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-001557-26 Sponsor Protocol Number: CV185-048 Start Date*: 2008-04-29
    Sponsor Name:Bristol Myers Squibb International Corporation
    Full Title: Apixaban Versus Acetylsalicyclic Acid (ASA) to Prevent Stroke in Atrial Fibrillation Patients Who Have Failed or are Unsuitable for Vitamin K Antagonist Treatment: A Randomized Double Blind Trial ...
    Medical condition: Patients with atrial fibrillation and at least one additional risk factor for stroke who have failed or are unsuitable for vitamin K antagonist therapy.
    Disease: Version SOC Term Classification Code Term Level
    13.1 10029205 - Nervous system disorders 10042244 Stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) FR (Completed) SE (Completed) BE (Completed) DE (Completed) FI (Completed) ES (Completed) DK (Completed) CZ (Completed) AT (Completed) GR (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-003200-23 Sponsor Protocol Number: 2013DR3084 Start Date*: 2016-04-21
    Sponsor Name:University Hospital Basel; Neurology
    Full Title: Biomarkers and antithrombotic treatment in cervical artery dissection (TREAT-CAD)
    Medical condition: cervical artery dissection
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2012-001398-97 Sponsor Protocol Number: 20110118 Start Date*: 2012-10-17
    Sponsor Name:Amgen Inc
    Full Title: A Double-blind, Randomized, Placebo-controlled, Multicenter Study Assessing the Impact of Additional LDL-Cholesterol Reduction on Major Cardiovascular Events When Evolocumab (AMG 145) is Used in Co...
    Medical condition: Dyslipidemia
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004861 10020604 Hypercholesterolemia LLT
    18.1 100000004861 10058110 Dyslipidemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) SK (Completed) PL (Completed) GR (Completed) LT (Completed) BE (Completed) IT (Completed) NL (Completed) DK (Completed) AT (Completed) HU (Completed) PT (Completed) ES (Completed) CZ (Completed) EE (Completed) IS (Completed) GB (Completed) DE (Completed) BG (Completed) SE (Completed) LV (Completed) IE (Completed) NO (Completed)
    Trial results: View results
    EudraCT Number: 2016-002683-14 Sponsor Protocol Number: DSE-EDO-01-15-EU Start Date*: 2017-01-12
    Sponsor Name:Daiichi Sankyo Europe GmbH
    Full Title: Evaluation of the safety and efficacy of an edoxaban-based compared to a vitamin K antagonist-based antithrombotic regimen following successful percutaneous coronary intervention (PCI) with stent p...
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    19.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) IE (Completed) GB (Completed) NL (Completed) DE (Completed) LT (Completed) ES (Completed) AT (Completed) HU (Completed) PT (Completed) BE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2011-002775-42 Sponsor Protocol Number: Start Date*: 2013-01-14
    Sponsor Name:Med. Uni. Wien, UK für Neurologie
    Full Title: Vienna Interventional Management of Stroke Study
    Medical condition: Acute stroke
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002657-36 Sponsor Protocol Number: HMRI2012101/1 Start Date*: 2015-11-13
    Sponsor Name:University of Newcastle
    Full Title: Tenecteplase versus Alteplase for Stroke Thrombolysis Evaluation (TASTE) Trial
    Medical condition: Acute Ischaemic Stroke
    Disease: Version SOC Term Classification Code Term Level
    22.1 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) BE (Completed) SE (Prematurely Ended) FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-005210-39 Sponsor Protocol Number: H7T-MC-TABY Start Date*: 2008-07-04
    Sponsor Name:Eli Lilly and Company
    Full Title: A Comparison of Prasugrel and Clopidogrel in Acute Coronary Syndrome (ACS) Subjects with Unstable Angina/Non-ST-Elevation Myocardial Infarction (UA/NSTEMI) Who are Medically Managed - The TRILOGY A...
    Medical condition: Treatment of Acute Coronary Syndrome in medically managed subjects enrolled within 10 days of the unstable angina/non-ST-segment elevation myocardial infarction (UA/NSTEMI) index event.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10051592 Acute coronary syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) SE (Completed) GB (Completed) HU (Completed) SK (Completed) FR (Completed) FI (Completed) DE (Completed) BE (Completed) AT (Completed) PT (Completed) LT (Completed) ES (Completed) GR (Completed) DK (Completed) CZ (Completed) IT (Completed) BG (Completed) IE (Completed) MT (Completed)
    Trial results: View results
    EudraCT Number: 2009-014730-22 Sponsor Protocol Number: SO3-01 Start Date*: 2009-08-31
    Sponsor Name:FONDAZIONE SALVATORE MAUGERI - CLINICA DEL LAVORO E DELLA RIABILITAZIONE
    Full Title: SO03-01 - EVALUATION OF THE EFFECT OF N-3 SUPPLEMENTATION ON FUNCTIONAL IMPROVEMENT IN POSTSTROKE PATIENTS
    Medical condition: Post ischemic stroke
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-001287-10 Sponsor Protocol Number: NBK241/2/2022 Start Date*: 2023-09-22
    Sponsor Name:Gdański Uniwersytet Medyczny
    Full Title: Treatment of acute ischemic stroke due to occlusion of a large vessel by mechanical thrombectomy in patients with unknown onset or not meeting the criteria for CT eligibility (ASPECTS <6) based on ...
    Medical condition: acute ischemic stroke caused by occlusion of a large vessel
    Disease: Version SOC Term Classification Code Term Level
    23.1 10029205 - Nervous system disorders 10084836 Malignant ischemic stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2010-021258-20 Sponsor Protocol Number: EAST Start Date*: 2011-06-15
    Sponsor Name:Kompetenznetz Vorhofflimmern e.V. (AFNET)
    Full Title: Early treatment of Atrial fibrillation for Stroke prevention Trial (EAST)
    Medical condition: Atrial fibrillation, stroke, heart failure, myocardial infarction, cognitive dysfunction
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    20.0 10007541 - Cardiac disorders 10019280 Heart failures HLGT
    21.1 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    20.0 10037175 - Psychiatric disorders 10009841 Cognitive and attention disorders and disturbances HLGT
    20.0 10007541 - Cardiac disorders 10028596 Myocardial infarction PT
    21.1 10029205 - Nervous system disorders 10019016 Haemorrhagic stroke PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) DK (Completed) NL (Completed) CZ (Completed) BE (Completed) ES (Completed) PL (Completed) IT (Ongoing)
    Trial results: View results
    EudraCT Number: 2012-000791-42 Sponsor Protocol Number: JVM-GLU-12 Start Date*: 2012-07-26
    Sponsor Name:FUNDACION INVESTIGACION BIOMEDICA HOSPITAL UNIVERSITARIO LA PRINCESA
    Full Title: OPEN, RANDOMIZED AND CONTROLLED STUDY OF SAFETY AND VIABILITY, TO EVALUATE THE NEUROPROTECTIVE EFFECT OF PLASMA GLUTAMATE DIALYSIS IN ACUTE ISCHEMIC STROKE.
    Medical condition: BRAIN ISCHEMIC STROKE IN ACUTE PHASE
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2019-002075-33 Sponsor Protocol Number: ENRICH-AF Start Date*: 2020-05-05
    Sponsor Name:Hamilton Health Sciences, through its Population Health Research Institute
    Full Title: Edoxaban for intracranial hemorrhage survivors with atrial fibrillation
    Medical condition: High risk atrial fibrillation patients with previous intracranial hemorrhage
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029205 - Nervous system disorders 10018985 Haemorrhage intracranial PT
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) NO (Prematurely Ended) DE (Trial now transitioned) ES (Ongoing) PT (Trial now transitioned) BE (Trial now transitioned) CZ (Trial now transitioned) AT (Trial now transitioned) IT (Trial now transitioned) SK (Trial now transitioned) DK (Trial now transitioned) GR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-004748-23 Sponsor Protocol Number: 2011080362 Start Date*: 2011-12-05
    Sponsor Name:Neurologisk Afdeling
    Full Title: Risk of apoplexia cerebri in clopidogrel non-responders.
    Medical condition: Apoplexia cerebri
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-005788-34 Sponsor Protocol Number: NL79578.100.21 Start Date*: 2022-03-31
    Sponsor Name:St. Antonius Hospital
    Full Title: Platelet inhibition versus direct oral anticoagulation in patients undergoing percutaneous closure of patent foramen ovale or atrial septal defect
    Medical condition: Atrial septal defect or patent foramen ovale indicated for percutaneous closure with an occluder device.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2012-000061-21 Sponsor Protocol Number: I1V-MC-EIAN Start Date*: 2012-10-25
    Sponsor Name:Eli Lilly and Company
    Full Title: Protocol I1V-MC-EIAN Assessment of Clinical Effects of Cholesteryl Ester Transfer Protein Inhibition with Evacetrapib in Patients at a High-Risk for Vascular Outcomes - the ACCELERATE Study
    Medical condition: High Risk Vascular Disease (HRVD)
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004866 10067825 Peripheral arterial disease LLT
    18.1 10007541 - Cardiac disorders 10051592 Acute coronary syndrome PT
    18.1 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    18.1 100000004852 10003602 Atherosclerosis cerebral LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SK (Prematurely Ended) EE (Prematurely Ended) DE (Prematurely Ended) BE (Prematurely Ended) SE (Prematurely Ended) HU (Prematurely Ended) AT (Completed) ES (Prematurely Ended) LT (Prematurely Ended) DK (Prematurely Ended) IT (Prematurely Ended) CZ (Prematurely Ended) PL (Prematurely Ended) BG (Prematurely Ended) NL (Prematurely Ended)
    Trial results: View results
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