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Clinical trials for Embryo

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44332   clinical trials with a EudraCT protocol, of which   7365   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    240 result(s) found for: Embryo. Displaying page 1 of 12.
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    EudraCT Number: 2009-017245-64 Sponsor Protocol Number: OG09/9146 Start Date*: 2010-09-07
    Sponsor Name:Leeds Teaching Hospitals NHS Trust
    Full Title: The effect of metformin co-treatment in hormone-replacement frozen embryo replacement cycles in women with polycystic ovary syndrome.
    Medical condition: Polycystic Ovary Syndrome
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-004266-25 Sponsor Protocol Number: 16-OBE001-005 Start Date*: 2017-02-24
    Sponsor Name:ObsEva S.A.
    Full Title: A phase 3, double-blind, randomized, placebo-controlled study to assess the safety and efficacy of a single oral administration of nolasiban to improve pregnancy rates following IVF or ICSI in Day ...
    Medical condition: Embryo implantation in women undergoing IVF or ICSI with Day 3 or Day 5 fresh embryo transfer cycles, in the context of Assisted Reproductive Technology (ART).
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10073184 Embryo transfer LLT
    Population Age: Adults Gender: Female
    Trial protocol: CZ (Completed) DE (Completed) DK (Completed) BE (Completed) HU (Completed) EE (Completed) ES (Completed) FI (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2014-002254-40 Sponsor Protocol Number: 14-OBE001-013 Start Date*: 2014-09-22
    Sponsor Name:ObsEva SA
    Full Title: A phase 2, double-blind, dose-finding, placebo-controlled study to assess the safety and efficacy of a single oral administration of OBE001 to improve embryo implantation following IVF or ICSI.
    Medical condition: Embryo implantation in women undergoing embyo transfer following IVF/ICSI in the context of Assisted Reproductive Technology (ART).
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004865 10073184 Embryo transfer LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed) BE (Completed) DK (Completed) CZ (Completed) ES (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2018-002910-11 Sponsor Protocol Number: 18-OBE001-010 Start Date*: 2018-11-08
    Sponsor Name:ObsEva SA
    Full Title: A phase 3, double-blind, randomized, placebo-controlled study to assess the safety and efficacy of a single oral administration of nolasiban to increase ongoing pregnancy rate following fresh singl...
    Medical condition: Embryo implantation in women undergoing IVF with Day 5 fresh embryo transfer cycles
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10073184 Embryo transfer LLT
    Population Age: Adults Gender: Female
    Trial protocol: HU (Completed) DK (Completed) ES (Ongoing) BE (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2013-000106-29 Sponsor Protocol Number: T5/2013 Start Date*: 2013-03-19
    Sponsor Name:Turku University Hospital
    Full Title: GnRH analog as a luteal phase support in frozen-thawed embryo transfer cycles. A Pilot study
    Medical condition: Infertility
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004872 10042391 Subfertility LLT
    Population Age: Adults Gender: Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001915-63 Sponsor Protocol Number: 13710 Start Date*: 2018-11-15
    Sponsor Name:University of Oxford / Clinical Trials and Research Governance
    Full Title: A randomised controlled pilot trial of the use of GnRH-antagonist pituitary suppression during medicated frozen-thawed embryo transfer (FET) cycles
    Medical condition: Infertility
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004872 10016398 Female infertility LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2018-003484-56 Sponsor Protocol Number: BOLDOS-18 Start Date*: 2019-12-26
    Sponsor Name:Miguel Caballero Campo
    Full Title: Efficacy of corifolitropin alfa in double ovarian stimulation compared with two conventional ovarian stimulation cycles for embryo accmulation in low responder patients. Multicenter randomized cont...
    Medical condition: Infertility in patients requiring in vitro fertilization treatment with poor ovarian response profile, defined by Bologna Criteria.
    Disease: Version SOC Term Classification Code Term Level
    21.0 10038604 - Reproductive system and breast disorders 10021926 Infertility PT
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-003813-42 Sponsor Protocol Number: 107015 Start Date*: 2006-12-21
    Sponsor Name:NV Organon
    Full Title: Follow-up protocol to collect the outcome of frozen-thawed embryo transfer cycles after cryopreservation of embryos in clinical trial 107012
    Medical condition: Controlled Ovarian Stimulation (COS) to induce the development of multiple follicles in patients participating in an Assisted Reproductive Technology (ART) program
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: SE (Completed) AT (Completed) CZ (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2008-002689-68 Sponsor Protocol Number: NL.23273.08 Start Date*: 2009-03-10
    Sponsor Name:Isala Klinieken, location Sophia
    Full Title: Cryo-thawed embryo transfer: natural versus artificial cycle. A non inferiority trial.
    Medical condition: Subfertility in need of IVF and IVF-ICSI treatment.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038604 - Reproductive system and breast disorders 10042391 Subfertility LLT
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-005331-14 Sponsor Protocol Number: 1411-MAD-079-CB Start Date*: 2015-08-19
    Sponsor Name:IVI Madrid
    Full Title: A prospective randomized trial to analyze the effect of the gonadotropin administered during controlled ovarian stimulation on embryo kinetics of development
    Medical condition: The study is proposed to analyze the effect of three types of gonadotropin on embryo quality and kinetics of development in women undergoing an assisted reporduction treatment
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-000599-33 Sponsor Protocol Number: LWH0646 Start Date*: 2006-08-21
    Sponsor Name:Liverpool Women's NHS Foundation Trust
    Full Title: Duration of luteal phase support with progesterone pessaries to improve the success rate in assisted reproduction cycles. A prospective randomised control trial.
    Medical condition: Women undergoing assisted conception
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-001014-15 Sponsor Protocol Number: S61372 Start Date*: 2018-06-26
    Sponsor Name:university hospital leuven
    Full Title: Frozen-thawed embryo transfer in a natural versus artificial cycle: a randomized clinical trial
    Medical condition: Patients with subfertility having frozen embryos after in vitro fertilization (IVF) or intracytoplasmatic sperm injection (ICSI)
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-002897-27 Sponsor Protocol Number: 18E-Prg06 Start Date*: 2018-12-21
    Sponsor Name:IBSA, Institut Biochimique, S.A.
    Full Title: A proof of concept, randomized, controlled clinical trial to assess the efficacy of subcutaneous progesterone (Prolutex) versus vaginal proges-terone (Progeffik) for endometrial preparation in wome...
    Medical condition: Infertility. Assisted Reproductive Tecniques.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10073184 Embryo transfer LLT
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: View results
    EudraCT Number: 2013-002482-19 Sponsor Protocol Number: 13EU/FSH01 Start Date*: 2013-12-12
    Sponsor Name:IBSA Institut Biochimique S.A.
    Full Title: Randomised clinical trial comparing highly purified FSH formulation (Fostimon®) and recombinant FSH (Gonal-F®) in GnRH-antagonist controlled ovarian hyperstimulation cycles.
    Medical condition: female infertility
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004872 10016398 Female infertility LLT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed) GB (Completed) ES (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2021-001399-40 Sponsor Protocol Number: RECHMPL20_0092 Start Date*: 2021-06-02
    Sponsor Name:University hospital of Montpellier
    Full Title: Amlodipine interest in HRT (Hormone Replacement Therapy) cycle for frozen embryo transfer in the uterine pulsatility indices correction: double-blind randomized controlled trial
    Medical condition: uterine arteries pulsalility index for patients awaiting frozen embryo transfer
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-004491-17 Sponsor Protocol Number: REMODEL Start Date*: 2021-03-31
    Sponsor Name:UZ Brussel
    Full Title: Dydrogesterone versus micronized vaginal progesterone (MVP) for luteal phase support (LPS) in hormone replacement therapy (HRT) frozen embryo transfer (FET) cycles.
    Medical condition: progesterone as luteal phase supplementation in frozen embryo transfer cycles
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-000201-84 Sponsor Protocol Number: AT2020_01 Start Date*: 2020-04-07
    Sponsor Name:Das Kinderwunsch Institut Schenk GmbH
    Full Title: Oral and intravenous iron substitution for the treatment of iron deficiency symptoms in the context of fertility treatment - an exploratory pilot study
    Medical condition: infertility
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-003645-16 Sponsor Protocol Number: 2019_0012 Start Date*: 2020-02-25
    Sponsor Name:Hopital Foch
    Full Title: Benefit of the GnRH agonist before frozen embryo transfer in patients with endometriosis and / or adenomyosis: randomized prospective study
    Medical condition: Frozen embryo transfer in patients with endometriosis and/or adenomyosis
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-003156-20 Sponsor Protocol Number: HRT_NC-FET Start Date*: 2019-03-15
    Sponsor Name:CRG UZ Brussel
    Full Title: Natural cycle versus hormone replacement therapy cycle for a frozen-thawed embryo transfer in PGT patients: a randomised trial.
    Medical condition: Female infertility
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-009323-11 Sponsor Protocol Number: Start Date*: 2009-10-14
    Sponsor Name:University of Oxford
    Full Title: A randomised controlled trial of natural versus hormone replacement therapy cycles in frozen embryo replacement IVF: a pilot study
    Medical condition: Infertility - specifically in those women intending to undertake a frozen embryo replacement treatment who have at least 3 embryos fozen in storage and who are planning a first or second frozen emb...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038604 - Reproductive system and breast disorders 10021926 Infertility PT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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