- Trials with a EudraCT protocol (64)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
64 result(s) found for: Eye Diseases AND Wet Macular Degeneration AND Retinal Diseases.
Displaying page 1 of 4.
| EudraCT Number: 2013-004567-30 | Sponsor Protocol Number: 1313.20 | Start Date*: 2014-04-15 | |||||||||||
| Sponsor Name:Boehringer Ingelheim RCV GmbH & Co KG | |||||||||||||
| Full Title: A single arm open label study to evaluate the pharmacodynamics and safety of a 4 wk treatment with BI 144807 in patients with newly diagnosed wet age related macular degeneration (wAMD) | |||||||||||||
| Medical condition: patients with newly diagnosed, unilateral, wet Are-Related Macular Degeneration | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: HU (Prematurely Ended) DE (Prematurely Ended) AT (Prematurely Ended) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2012-005500-18 | Sponsor Protocol Number: VITCLEAR | Start Date*: 2013-11-18 | ||||||||||||||||
| Sponsor Name:King's College Hospital NHS Foundation Trust [...] | ||||||||||||||||||
| Full Title: A pharmacokinetic study: ranibizumab, aflibercept and the effect of vitrectomy | ||||||||||||||||||
| Medical condition: Age-related macular degeneration | ||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
| Trial protocol: GB (Completed) | ||||||||||||||||||
| Trial results: View results | ||||||||||||||||||
| EudraCT Number: 2012-003763-22 | Sponsor Protocol Number: BAY73-4506/15984 | Start Date*: 2014-07-02 | ||||||||||||||||||||||||||
| Sponsor Name:Bayer HealthCare AG | ||||||||||||||||||||||||||||
| Full Title: A combined Phase IIa / IIb study of the efficacy, safety, and tolerability of repeated topical doses of regorafenib eye drops, in treatment-naïve subjects with neovascular age related macular degen... | ||||||||||||||||||||||||||||
| Medical condition: neovascular age related macular degeneration | ||||||||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||
| Trial protocol: HU (Prematurely Ended) DE (Prematurely Ended) CZ (Prematurely Ended) SK (Prematurely Ended) | ||||||||||||||||||||||||||||
| Trial results: View results | ||||||||||||||||||||||||||||
| EudraCT Number: 2014-002168-34 | Sponsor Protocol Number: FNB-OK-2013-01 | Start Date*: 2014-12-09 | |||||||||||||||||||||
| Sponsor Name:Doc. MUDr. Petr Kolář, PhD, Oční klinika FN Brno | |||||||||||||||||||||||
| Full Title: Study To Determine Efficacy of Aflibercept For Treatment Of Retinal Angiomatous Proliferation Secondary To Age Related Macular Degeneration | |||||||||||||||||||||||
| Medical condition: Retinal angiomatous proliferation secondary to wet age related macular degeneration. | |||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
| Trial protocol: CZ (Completed) | |||||||||||||||||||||||
| Trial results: (No results available) | |||||||||||||||||||||||
| EudraCT Number: 2012-004078-24 | Sponsor Protocol Number: TAPAS | Start Date*: 2013-01-24 | ||||||||||||||||
| Sponsor Name:King's College London [...] | ||||||||||||||||||
| Full Title: Intravitreal Tissue Plasminogen Activator (tPA), Perfluoropropane (C3F8), and Ranibizumab for Neovascular Age-Related Macular Degeneration and Submacular Haemorrhage (TAPAS): A Randomized, Double-M... | ||||||||||||||||||
| Medical condition: Sub-macular haemorrhage secondary to wet macular degeneration | ||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
| Trial protocol: GB (Completed) | ||||||||||||||||||
| Trial results: (No results available) | ||||||||||||||||||
| EudraCT Number: 2015-001961-20 | Sponsor Protocol Number: FYB201-C2015-01-P3 | Start Date*: 2015-11-24 | ||||||||||||||||
| Sponsor Name:Bioeq GmbH | ||||||||||||||||||
| Full Title: Efficacy and safety of the biosimilar ranibizumab FYB201 in comparison to Lucentis in patients with neovascular age-related macular degeneration (COLUMBUS-AMD) | ||||||||||||||||||
| Medical condition: Subfoveal neovascular age-related macular degeneration | ||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
| Trial protocol: CZ (Completed) AT (Completed) DE (Completed) HU (Completed) ES (Completed) FR (Completed) GB (Completed) IT (Completed) | ||||||||||||||||||
| Trial results: View results | ||||||||||||||||||
| EudraCT Number: 2010-021968-15 | Sponsor Protocol Number: ID_2909 | Start Date*: 2010-08-06 | |||||||||||
| Sponsor Name:AZIENDA OSPEDALIERA ISTITUTI OSPITALIERI DI VERONA | |||||||||||||
| Full Title: NOT RANDOMISED OPEN LABEL STUDY TO COMPARE EFFICACY OF BEVACIZUMAB (AVASTIN, ROCHE) VERSUS RANIBIZUMAB (LUCENTIS, NOVARTIS) ADMINISTERED BY INTRAVITREAL INJECTION IN PATIENTS WITH EXUDATIVE AGE REL... | |||||||||||||
| Medical condition: exudative age related macular degeneration | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: IT (Ongoing) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2010-018741-65 | Sponsor Protocol Number: OPH1001A | Start Date*: 2010-04-21 | ||||||||||||||||
| Sponsor Name:OPHTHOTECH CORPORATION | ||||||||||||||||||
| Full Title: A PHASE 2, RANDOMIZED, DOUBLE-MASKED, CONTROLLED TRIAL TO ESTABLISH THE SAFETY AND EFFICACY OF INTRAVITREOUS INJECTIONS OF E10030 (ANTI-PDGF PEGYLATED APTAMER) GIVEN IN COMBINATION WITH LUCENTIS® I... | ||||||||||||||||||
| Medical condition: Subfoveal choroidal neovascularization secondary to age-related macular degeneration (AMD) | ||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
| Trial protocol: LV (Completed) FR (Completed) BE (Completed) DE (Completed) ES (Completed) HU (Completed) IT (Completed) AT (Completed) | ||||||||||||||||||
| Trial results: View results | ||||||||||||||||||
| EudraCT Number: 2013-003333-15 | Sponsor Protocol Number: CRFB002AIT02 | Start Date*: 2013-11-15 | |||||||||||
| Sponsor Name:NOVARTIS FARMA | |||||||||||||
| Full Title: A 12 months, prospective, multicenter, open-label, single arm interventional study assessing the safety and tolerability of 0.5 mg ranibizumab in mono/bilateral wet AMD patients in eyes with BCVA b... | |||||||||||||
| Medical condition: Mono/bilateral Wet Age related Macular Degeneration (wAMD) in eyes with Best Corrected Visual Acuity (BCVA) below 2/10 and/or second affected eye . | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: IT (Completed) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2020-004736-24 | Sponsor Protocol Number: OPT-302-1004 | Start Date*: 2021-07-19 | |||||||||||||||||||||
| Sponsor Name:Opthea Limited | |||||||||||||||||||||||
| Full Title: A Phase 3, Multicentre, Double-masked, Randomised Study to Evaluate the Efficacy and Safety of Intravitreal OPT-302 in Combination with Ranibizumab, Compared with Ranibizumab Alone, in Participants... | |||||||||||||||||||||||
| Medical condition: Neovascular age-related macular degeneration (wet AMD) | |||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
| Trial protocol: FR (Trial now transitioned) DE (Trial now transitioned) CZ (Trial now transitioned) GR (Trial now transitioned) HU (Trial now transitioned) DK (Trial now transitioned) BG (Completed) PL (Trial now transitioned) ES (Ongoing) LV (Trial now transitioned) IT (Trial now transitioned) | |||||||||||||||||||||||
| Trial results: (No results available) | |||||||||||||||||||||||
| EudraCT Number: 2020-001061-37 | Sponsor Protocol Number: KS301P103 | Start Date*: 2020-12-11 | |||||||||||||||||||||||||||||||
| Sponsor Name:Kodiak Sciences Inc. | |||||||||||||||||||||||||||||||||
| Full Title: A Prospective, Randomized, Double-masked, Active Comparator-controlled, Multi-center, Two-arm, Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 Compared with Intravitreal A... | |||||||||||||||||||||||||||||||||
| Medical condition: Macular edema secondary to retinal vein occlusion | |||||||||||||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||||||||||||
| Trial protocol: LV (Prematurely Ended) DE (Completed) SK (Prematurely Ended) CZ (Prematurely Ended) FR (Prematurely Ended) HU (Completed) IT (Prematurely Ended) | |||||||||||||||||||||||||||||||||
| Trial results: View results | |||||||||||||||||||||||||||||||||
| EudraCT Number: 2014-000103-27 | Sponsor Protocol Number: Eylea-2014 | Start Date*: 2014-03-12 |
| Sponsor Name: | ||
| Full Title: Plasma levels of vascular endothelial growth factor before and after intravitreal injection of aflibercept in patients with exudative age-related macular degeneration. | ||
| Medical condition: Exudative age-related macular degeneration (AMD) | ||
| Disease: | ||
| Population Age: Adults | Gender: Male, Female | |
| Trial protocol: NO (Completed) | ||
| Trial results: (No results available) | ||
| EudraCT Number: 2017-002698-20 | Sponsor Protocol Number: OPT-302-1002 | Start Date*: 2018-02-07 | |||||||||||||||||||||
| Sponsor Name:Opthea Ltd | |||||||||||||||||||||||
| Full Title: A dose-ranging study of intravitreal OPT-302 in combination with ranibizumab, compared with ranibizumab alone, in participants with neovascular age-related macular degeneration (wet AMD) | |||||||||||||||||||||||
| Medical condition: Neovascular age-related macular degeneration (wet AMD) | |||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
| Trial protocol: CZ (Completed) LV (Completed) GB (Completed) ES (Completed) IT (Completed) | |||||||||||||||||||||||
| Trial results: View results | |||||||||||||||||||||||
| EudraCT Number: 2011-002526-43 | Sponsor Protocol Number: 150998-001 | Start Date*: 2012-01-30 | |||||||||||
| Sponsor Name:Allergan Limited | |||||||||||||
| Full Title: Single and Repeat Dose Study of the Safety and Efficacy of AGN-150998 in Patients with Exudative Age-related Macular Degeneration | |||||||||||||
| Medical condition: Exudative Age-related Macular Degeneration | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: DE (Completed) AT (Completed) IT (Completed) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2008-004844-35 | Sponsor Protocol Number: TG-MV-005 | Start Date*: 2009-07-01 | |||||||||||||||||||||
| Sponsor Name:ThromboGenics NV | |||||||||||||||||||||||
| Full Title: A randomized, sham-injection controlled, double-masked, multicenter trial of microplasmin intravitreal injection for treatment of exudative age-related macular degeneration (AMD). | |||||||||||||||||||||||
| Medical condition: Patients with exudative AMD with focal vitreomacular adhesion | |||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
| Trial protocol: FR (Completed) GB (Completed) DE (Completed) IT (Completed) BE (Completed) | |||||||||||||||||||||||
| Trial results: View results | |||||||||||||||||||||||
| EudraCT Number: 2010-021923-29 | Sponsor Protocol Number: 10032011 | Start Date*: 2011-08-11 | |||||||||||
| Sponsor Name:Universitätsklinik für Augenheilkunden und Optometrie, Medizinische Universität Wien | |||||||||||||
| Full Title: Management of recurrent or persistent choroidal neovascularization secondary to age-related macular degeneration A prospective, randomized, clinical study | |||||||||||||
| Medical condition: Neovascular age-related macular degeneration | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: AT (Completed) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2018-003428-35 | Sponsor Protocol Number: KSI-CL-102 | Start Date*: 2020-01-03 | |||||||||||||||||||||
| Sponsor Name:Kodiak Sciences Inc. | |||||||||||||||||||||||
| Full Title: A Phase 2b/3, Prospective, Randomised, Double-masked, Active Comparator-controlled, Multi-center Study to Investigate the Efficacy and Safety of Repeated Intravitreal Administration of KSI-301 in S... | |||||||||||||||||||||||
| Medical condition: Neovascular (Wet) Age-related Macular Degeneration | |||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
| Trial protocol: LV (Prematurely Ended) GB (GB - no longer in EU/EEA) DE (Prematurely Ended) CZ (Prematurely Ended) SK (Prematurely Ended) PL (Prematurely Ended) ES (Prematurely Ended) IT (Prematurely Ended) | |||||||||||||||||||||||
| Trial results: View results | |||||||||||||||||||||||
| EudraCT Number: 2009-014280-38 | Sponsor Protocol Number: 09OY006 | Start Date*: 2009-11-13 | |||||||||||
| Sponsor Name:Nottingham University Hospitals NHS Trust | |||||||||||||
| Full Title: A randomised controlled trial of standard and low dose Avastin® for Neovascular Macular Degeneration in the East Midlands | |||||||||||||
| Medical condition: Neovascular ("wet") age-related macular degeneration | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: GB (Prematurely Ended) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2015-001394-41 | Sponsor Protocol Number: 00170 | Start Date*: 2015-06-10 |
| Sponsor Name:Raimo Tuuminen | ||
| Full Title: Predictability of response of aflibercept treatment for wet age-related macular degeneration under the treat-and-moderate extend regimen (TMER) treatment model | ||
| Medical condition: Wet age-related macular degeneration | ||
| Disease: | ||
| Population Age: Adults, Elderly | Gender: Male, Female | |
| Trial protocol: FI (Completed) | ||
| Trial results: (No results available) | ||
| EudraCT Number: 2020-004694-46 | Sponsor Protocol Number: OPT-302-1005 | Start Date*: 2021-08-06 | |||||||||||||||||||||
| Sponsor Name:Opthea Limited | |||||||||||||||||||||||
| Full Title: A Phase 3, Multicentre, Double-masked, Randomised Study to Evaluate the Efficacy and Safety of Intravitreal OPT-302 in Combination with Aflibercept, Compared with Aflibercept Alone, in Participants... | |||||||||||||||||||||||
| Medical condition: Neovascular Age-related Macular Degeneration (wet AMD) | |||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
| Trial protocol: SK (Trial now transitioned) CZ (Trial now transitioned) DE (Trial now transitioned) LT (Trial now transitioned) DK (Completed) FR (Trial now transitioned) LV (Trial now transitioned) EE (Trial now transitioned) NL (Trial now transitioned) ES (Ongoing) BG (Trial now transitioned) IT (Trial now transitioned) HR (Trial now transitioned) | |||||||||||||||||||||||
| Trial results: (No results available) | |||||||||||||||||||||||
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