Clinical Trials Register

Trials with a EudraCT protocol (20)
Paediatric studies in scope of Art45 of the Paediatric Regulation (0)

20 result(s) found for: PTLD. Displaying page 1 of 1.

EudraCT Number: 2015-005454-35

Sponsor Protocol Number: RG_15-235

Start Date*: 2016-09-23

Sponsor Name:University of Birmingham

Full Title: Risk-stratified sequential Treatment with Ibrutinib and Rituximab (IR) and IR-CHOP for De-novo post-transplant Lymphoproliferative disorder (PTLD)

Medical condition: Post-transplant lymphoproliferative disorder

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10051358	Post transplant lymphoproliferative disorder	PT

Population Age: Adolescents, Under 18, Adults, Elderly

Gender: Male, Female

Trial protocol: GB (GB - no longer in EU/EEA)

Trial results: (No results available)

EudraCT Number: 2013-004479-11

Sponsor Protocol Number: DPTLDSG-IIT-PTLD-2

Start Date*: 2014-09-19

Sponsor Name:DIAKO Ev. Diakonie-Krankenhaus Bremen gGmbH

Full Title: Risk-stratified Sequential Treatment of Post-transplant Lymphoproliferative Disease (PTLD) With 4 Courses of Rituximab SC Followed by 4 Courses of Rituximab SC, 4 Courses of Rituximab SC Combined W...

Medical condition: Previously untreated CD20-positive lymphoproliferative disorder (PTLD) following solid organ transplantation

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	18.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10051358	Post transplant lymphoproliferative disorder	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Completed)

Trial results: (No results available)

EudraCT Number: 2017-002949-30

Sponsor Protocol Number: ATA129-EBV-302

Start Date*: 2020-07-17

Sponsor Name:Atara Biotherapeutics, Inc.

Full Title: Multicenter, Open Label, Phase 3 Study of Tabelecleucel for Solid Organ or Allogeneic Hematopoietic Cell Transplant Subjects with Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative D...

Medical condition: Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease

Disease:	Version	SOC Term	Classification Code	Term	Level
	21.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10068349	Epstein-Barr virus associated lymphoproliferative disorder	PT
	21.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10075146	Post transplant Epstein-Barr virus associated lymphoproliferative disorder	LLT

Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly

Gender: Male, Female

Trial protocol: GB (GB - no longer in EU/EEA) DE (Completed) FR (Trial now transitioned) ES (Ongoing) AT (Trial now transitioned) BE (Trial now transitioned) IT (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2020-000492-21	Sponsor Protocol Number: 7678	Start Date*: 2021-06-11
Sponsor Name:Les Hôpitaux Universitaires de Strasbourg
Full Title: Multicenter randomized two arms study evaluating the efficacy of prophylactic Rituximab in adult EBV negative kidney transplant recipients on incidence of EBV primary infection and post-transplant ...
Medical condition: Kidney transplantation Epstein Barr virus
Disease:
Population Age: Adults, Elderly		Gender: Male, Female
Trial protocol: FR (Trial now transitioned)
Trial results: (No results available)

EudraCT Number: 2020-000177-25

Sponsor Protocol Number: ATA129-EBV-205

Start Date*: 2021-01-04

Sponsor Name:Atara Biotherapeutics, Inc.

Full Title: An Open-label, Single-arm, Multicohort, Phase 2 Study to Assess the Efficacy and Safety of Tabelecleucel in Subjects with Epstein-Barr Virus-associated Diseases

Medical condition: • EBV+ primary imunodeficiency lymphoproliferative disease (LPD) • EBV+ LPD in the setting of acquired (non-congenital) immunodeficiency • EBV+ post-transplant LPD involving the central nervous ...

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	21.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10068349	Epstein-Barr virus associated lymphoproliferative disorder	PT

Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly

Gender: Male, Female

Trial protocol: FR (Trial now transitioned) AT (Trial now transitioned) BE (Trial now transitioned) IT (Trial now transitioned) ES (Ongoing)

Trial results: (No results available)

EudraCT Number: 2007-003023-20

Sponsor Protocol Number: UCL-PLTP-002

Start Date*: 2008-09-11

Sponsor Name:Cliniques universitaires Saint-Luc

Full Title: TACROLIMUS – DACLIZUMAB - MYCOPHENOLATE MOFETIL IMMUNE PROPHYLAXIS IN PEDIATRIC LIVER TRANSPLANTATION. An open, pilot, investigator-driven study in 20 recipients

Medical condition: Liver transplantation

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10024678	Liver failure	LLT

Population Age: Infants and toddlers, Children, Adolescents, Under 18

Gender: Male, Female

Trial protocol: BE (Completed)

Trial results: View results

EudraCT Number: 2020-005197-10

Sponsor Protocol Number: VT3996-202

Start Date*: 2021-10-01

Sponsor Name:Viracta Therapeutics, Inc.

Full Title: An Open-Label, Phase 2 Trial of Nanatinostat in Combination with Valganciclovir in Patients with Epstein-Barr Virus-Positive (EBV+) Relapsed/Refractory Lymphomas (NAVAL-1)

Medical condition: Epstein-Barr Virus-Positive (EBV+) Relapsed/Refractory Lymphomas

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	21.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10071441	Epstein-Barr virus associated lymphoma	PT

Population Age: Adolescents, Under 18, Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Trial now transitioned) FR (Trial now transitioned) IT (Trial now transitioned) ES (Ongoing)

Trial results: (No results available)

EudraCT Number: 2012-003033-42

Sponsor Protocol Number: UKER-BLZ-PH1

Start Date*: 2013-09-12

Sponsor Name:Universitätsklinikum Erlangen

Full Title: Prospective, open-label, multicentre clinical trial, phase I/IIa, to investigate the safety and tolerability of allogeneic B-cell concentrates CD3+-depleted, CD19+-enriched, cryopreserved (single a...

Medical condition: Status post allogeneic stem cell transplantation

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	19.0	100000004865	10067862	Allogeneic stem cell transplantation	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Completed)

Trial results: View results

EudraCT Number: 2007-000468-26

Sponsor Protocol Number: Rit EBV

Start Date*: 2007-01-11

Sponsor Name:OSPEDALE POLICLINICO S. MATTEO

Full Title: A phase I/II multicentre study to evaluate the safety and efficacy of rituximab (monoclonal antibody anti-CD20) for prevention and/or therapy of EBV-disease.

Medical condition: NOT AVAILABLE

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10015108	Epstein-Barr virus infection	LLT

Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18

Gender: Male, Female

Trial protocol: IT (Completed)

Trial results: (No results available)

EudraCT Number: 2007-006516-31	Sponsor Protocol Number: IT1850071	Start Date*: 2008-06-03
Sponsor Name:University Hospital Freiburg, represented by the Executive Medical Director (LÄD)
Full Title: Triple arm, prospective-randomised multi centre study phase IV to evaluate calcineurin inhibitor reduced, steroid free immunosuppression after renal transplantation in low-risk patients (HARMONY-St...
Medical condition: One year follow-up in patients after receiving renal transplantation
Disease:
Population Age: Adults, Elderly		Gender: Male, Female
Trial protocol: DE (Completed)
Trial results: View results

EudraCT Number: 2016-003286-26

Sponsor Protocol Number: PCYC-1140-IM

Start Date*: 2017-04-18

Sponsor Name:Pharmacyclics LLC

Full Title: A Randomized, Double-Blind Phase 3 Study of Ibrutinib in Combination With Corticosteroids versus Placebo in Combination With Corticosteroids in Subjects with New Onset Chronic Graft Versus Host Dis...

Medical condition: Chronic Graft Versus Host Disease (cGVHD)

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.1	10021428 - Immune system disorders	10066261	Chronic graft versus host disease	PT

Population Age: Adolescents, Under 18, Adults

Gender: Male, Female

Trial protocol: HU (Completed) DE (Completed) ES (Completed) AT (Completed) HR (Completed) IT (Completed) FR (Completed)

Trial results: View results

EudraCT Number: 2009-012198-36	Sponsor Protocol Number: NTx-RTx-LD-001	Start Date*: 2010-01-12
Sponsor Name:Universitätsklinikum Giessen und Marburg - Standort Giessen
Full Title: Einfluss von Rituximab-Induktion und Lebendspende auf Immunregulation und Viruskontrolle nach Nierentransplantation - eine prospektive Pilotstudie
Medical condition: Living donor and deceased donor kidney transplantation. ABO compatible and ABO incompatible kidney transplantation.
Disease:
Population Age: Adults, Elderly		Gender: Male, Female
Trial protocol: DE (Completed)
Trial results: View results

EudraCT Number: 2011-001822-81

Sponsor Protocol Number: TJT1106

Start Date*: 2011-09-06

Sponsor Name:CHU-Ulg

Full Title: Infusion of third-party mesenchymal stem cells after renal or liver transplantation: a phase I-II, open-label, clinical study.

Medical condition: Liver failure: end-stage liver diseases, including cirrhosis, primary liver cancer, fulminant hepatic failure and numerous other metabolic or congenital hepatic diseases. Kidney failure: end-st...

Disease:	Version	SOC Term	Classification Code	Term	Level
	14.0	10042613 - Surgical and medical procedures	10050434	Prophylaxis against liver transplant rejection	LLT
	14.0	10042613 - Surgical and medical procedures	10050436	Prophylaxis against renal transplant rejection	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: BE (Completed)

Trial results: (No results available)

EudraCT Number: 2005-000743-29

Sponsor Protocol Number: 2142002

Start Date*: 2009-07-02

Sponsor Name:Heads Study Group

Full Title: Treatment of patients with post-transplant lymphoproliferative disorder (PILD) with a sequential treatment consisting of anti-CD20 antibody rituximab and CHOP + GCSF chemotherapy (including first, ...

Medical condition: Post-tranplant lymphoproliferative disorder (PTLD)

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10012818	Diffuse large B-cell lymphoma	LLT

Population Age:

Gender: Male, Female

Trial protocol: BE (Completed)

Trial results: (No results available)

EudraCT Number: 2015-004137-27	Sponsor Protocol Number: ScanCLAD_1.0(formerVersion_0.1)	Start Date*: 2016-05-19
Sponsor Name:Transplantationscentrum, Sahlgrenska Universitetssjukhuset
Full Title: A Scandinavian controlled, randomized, open-label, and multi-centre study evaluating if once-daily tacrolimus or twice-daily cyclosporin, reduces the 3-year incidence of chronic lung allograft dysf...
Medical condition: Recipients of primary bilateral lung transplant allograft
Disease:
Population Age: Adults		Gender: Male, Female
Trial protocol: SE (Prematurely Ended) FI (Prematurely Ended) DK (Prematurely Ended)
Trial results: (No results available)

EudraCT Number: 2008-003241-89

Sponsor Protocol Number: LCP-Tacro 3002

Start Date*: 2010-11-05

Sponsor Name:LifeCycle Pharma A/S

Full Title: A Phase 3, Double-Blind, Double-Dummy, Multi-Center, Prospective, Randomized Study of the Efficacy and Safety of LCP-Tacro™ Tablets, Once Daily, Compared to Prograf® Capsules, Twice Daily, in Combi...

Medical condition: Prevention of Acute Allograft Rejection in De Novo Adult Kidney Transplant Recipients

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	12.1		10050436	Prophylaxis against renal transplant rejection	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: FR (Completed) DE (Completed) SE (Completed) ES (Completed) IT (Completed)

Trial results: (No results available)

EudraCT Number: 2015-002846-30

Sponsor Protocol Number: NLG-LBC-06

Start Date*: 2016-09-13

Sponsor Name:HUS-The Hospital District of Helsinki and Uusimaa

Full Title: BIO-CHIC-Study BIOmarker driven and dose intensified CHemoImmunotherapy with early CNS prophylaxis in patients less than 65 years with high risk diffuse large B-cell lymphoma

Medical condition: Diffuse large B-cell lymphoma

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	19.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10012818	Diffuse large B-cell lymphoma	PT

Population Age: Adults

Gender: Male, Female

Trial protocol: FI (Completed) DK (Completed) NO (Completed) SE (Completed)

Trial results: (No results available)

EudraCT Number: 2019-002419-24

Sponsor Protocol Number: RG_19-116

Start Date*: 2020-09-23

Sponsor Name:The University of Birmingham

Full Title: A multi-centre phase II trial of GvHD prophylaxis following unrelated donor stem cell transplantation comparing Thymoglobulin vs. Calcineurin inhibitor or Sirolimus-based post-transplant cyclophosp...

Medical condition: Acute Myeloid Leukaemia, Acute lymphoblastic leukaemia, Chronic myelomonocytic leukemia, Myelodysplastic syndromes, Non-Hodgkin lymphoma, Hodgkin lymphoma, Multiple myeloma, Chronic lymphocytic leu...

Disease:	Version	SOC Term	Classification Code	Term	Level
	21.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10000880	Acute myeloid leukaemia	PT
	21.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10000844	Acute lymphoblastic leukaemia	LLT
	21.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10009018	Chronic myelomonocytic leukaemia	PT
	21.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10028533	Myelodysplastic syndrome	PT
	22.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10029547	Non-Hodgkin's lymphoma	PT
	20.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10020328	Hodgkin's lymphoma	LLT
	21.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10028228	Multiple myeloma	LLT
	21.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10008958	Chronic lymphocytic leukaemia	PT
	21.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10009013	Chronic myeloid leukaemia	PT
	20.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10028537	Myelofibrosis	PT

Population Age: Under 18, Adults, Elderly

Gender: Male, Female

Trial protocol: GB (GB - no longer in EU/EEA)

Trial results: (No results available)

EudraCT Number: 2008-000252-28

Sponsor Protocol Number: SHCVOLT1

Start Date*: 2009-03-13

Sponsor Name:Cambridge University Hospitals NHS Foundation Trust

Full Title: A Multi-Centre Prospective Controlled Trial Comparing Calcineurin Inhibitor Monotherapy With Sirolimus Monotherapy in Hepatitis C Infected Patients with Hepatic Fibrosis Following Liver Transplanta...

Medical condition: Patients who have undergone liver transplantation and are infected with Hepatitis C virus.

Disease:	Version	SOC Term	Classification Code	Term	Level
	9.1		10052779	Transplant rejections	HLT
	9.1		10024970	Respiratory tract infections	HLGT
	9.1		10046577	Urinary tract infections	HLT
	9.1		10001032	Acute pyelonephritis	LLT
	9.1		10040072	Septicaemia	LLT
	9.1		10019972	Herpes viral infections	HLT
	9.1		10028440	Mycobacterial infectious disorders	HLGT
	9.1		10015107	Epstein-Barr viral infections	HLT
	9.1		10011831	Cytomegalovirus infection	LLT
	9.1		10019974	Herpes zoster	LLT
	9.1		10058872	Fungal sepsis	LLT
	9.1		10040808	Skin cancer	PT
	9.1		10051358	Post transplant lymphoproliferative disorder	LLT
	9.1		10043555	Thrombocytopenias	HLT
	9.1		10037561	Purpura thrombocytopenic	LLT
	9.1		10002034	Anaemia	PT
	9.1		10018932	Haemolytic uraemic syndrome	PT
	9.1		10024384	Leukopenia	PT
	9.1		10029355	Neutropenias	HLT
	9.1		10033661	Pancytopenia	PT
	9.1		10013505	Disturbance of liver function tests	LLT
	9.1		10002218	Anaphylaxis	LLT
	9.1		10002425	Angioedemas	HLT
	9.1		10015665	Exfoliative dermatitis	LLT
	9.1		10020764	Hypersensitivity vasculitis	LLT
	9.1		10021015	Hypokalaemia	PT
	9.1		10021058	Hypophosphataemia	PT
	9.1		10020603	Hypercholesterolaemia	PT
	9.1		10020635	Hyperglycaemia	PT
	9.1		10020869	Hypertriglyceridaemia	PT
	9.1		10043071	Tachycardia	PT
	9.1		10034474	Pericardial effusion	PT
	9.1		10048642	Lymphocele	PT
	9.1		10051055	Deep vein thrombosis	PT
	9.1		10037377	Pulmonary embolism	PT
	9.1		10025282	Lymphoedema	PT
	9.1		10035742	Pneumonitis	PT
	9.1		10035598	Pleural effusion	PT
	9.1		10015090	Epistaxis	PT
	9.1		10037394	Pulmonary haemorrhage	PT
	9.1		10000081	Abdominal pain	PT
	9.1		10012735	Diarrhoea	PT
	9.1		10042128	Stomatitis	PT
	9.1		10033645	Pancreatitis	PT
	9.1		10000496	Acne	PT
	9.1		10037844	Rash	PT
	9.1		10003239	Arthralgia	PT
	9.1		10031264	Osteonecrosis	PT
	9.1		10037032	Proteinuria	PT
	9.1		10029164	Nephrotic syndrome	PT
	9.1		10030124	Oedema peripheral	PT
	9.1		10021519	Impaired healing	PT
	9.1		10030095	Oedema	PT
	9.1		10037660	Pyrexia	PT
	9.1		10005630	Blood lactate dehydrogenase increased	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Prematurely Ended)

Trial results: View results

EudraCT Number: 2007-001657-26

Sponsor Protocol Number: KCH-BMT-07-1.0

Start Date*: 2008-02-29

Sponsor Name:King's College Hospital NHS Foundation Trust

Full Title: Single Centre Phase II Pilot study of Unrelated Cord Blood Transplantation in Patients with Poor Risk Haematological Malignancies.

Medical condition: 1. Acute, chronic leukaemia or myelodysplastic syndrome for which allogeneic transplantation is considered as the best treatment option. 2. Acute lymphoblastic leukaemia (ALL) 3. Non-Hodgkin’s l...

Disease:	Version	SOC Term	Classification Code	Term	Level
	9.1		10000880	Acute myeloid leukaemia	LLT
	9.1		10028533	Myelodysplastic syndrome	LLT
	9.1		10009013	Chronic myeloid leukaemia	LLT
	9.1		10000844	Acute lymphoblastic leukaemia	LLT
	9.1		10020328	Hodgkin's lymphoma	LLT
	9.1		10029593	Non-Hodgkin's lymphoma NOS	LLT
	9.1		10003892	B-cell chronic lymphocytic leukaemia/prolymphocytic leukaemia/small lymphocytic lymphoma	LLT
	9.1		10002968	Aplastic anaemia, unspecified	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: View results

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Clinical trials for PTLD