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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 1,459 of 2,219.
    EudraCT Number: 2011-004977-10 Sponsor Protocol Number: 08meInnereA_GALACTIC Start Date*: 2013-07-25
    Sponsor Name:University Hospital Basel, Cardiology
    Full Title: Goal-directed Afterload Reduction in Acute Congestive Cardiac Decompensation Study
    Medical condition: - acute decompensated heart failure
    Disease: Version SOC Term Classification Code Term Level
    19.0 10042613 - Surgical and medical procedures 10054112 Hospitalisation PT
    19.0 10018065 - General disorders and administration site conditions 10011906 Death PT
    19.0 10042613 - Surgical and medical procedures 10022519 Intensive care PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prohibited by CA) BG (Completed)
    Trial results: View results
    EudraCT Number: 2015-001832-39 Sponsor Protocol Number: LPS14060 Start Date*: 2015-11-03
    Sponsor Name:sanofi-aventis Groupe
    Full Title: A twenty-six week, randomized, open-label, 2-arm parallel group real world pragmatic trial to assess the clinical and health outcomes benefit of transition to Toujeo compared to standard of care in...
    Medical condition: Type 2 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    18.1 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) IE (Completed) FI (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-005431-41 Sponsor Protocol Number: BN40900(SA-309JG) Start Date*: 2017-10-16
    Sponsor Name:F. Hoffmann-La Roche Ltd.
    Full Title: A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Satralizumab (SA237) as Monotherapy in Patients With Neuromyelitis Optica (NMO) and...
    Medical condition: Neuromyelitis optica (NMO) and NMO spectrum disorder (MNOSD)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10029322 Neuromyelitis optica LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed) RO (Completed) HR (Completed)
    Trial results: View results
    EudraCT Number: 2018-004563-31 Sponsor Protocol Number: Au18-12 Start Date*: 2022-07-25
    Sponsor Name:Centre Hospitalier Universitaire de Reims
    Full Title: Cell therapy in Critical Limb Ischemia by implantation of allogeneic umbilical cord-derived mesenchymal stem cells
    Medical condition: Evaluation of the feasibility and systemic and local tolerance of an implantation, via intramuscular route, of allogenic HB-MSC1, associated with a revascularization procedure, in patients sufferin...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-005307-83 Sponsor Protocol Number: CL04041023 Start Date*: 2017-03-03
    Sponsor Name:R-Pharm
    Full Title: A Randomized, Double-Blind, Parallel-Group, Placebo- and Active-Controlled, Multicenter Phase III Study of the Efficacy and Safety of Olokizumab in Subjects with Moderately to Severely Active Rheum...
    Medical condition: Moderately to Severely Active Rheumatoid Arthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LV (Completed) CZ (Completed) DE (Completed) LT (Completed) HU (Completed) PL (Completed) BG (Completed) RO (Completed)
    Trial results: View results
    EudraCT Number: 2015-005555-27 Sponsor Protocol Number: ESR-14-10473 Start Date*: 2017-09-12
    Sponsor Name:University Hospital Basel
    Full Title: Prevention of Cerebral Ischaemia in Stent Treatment for Carotid Artery Stenosis - A randomised multi-centre phase II trial comparing Ticagrelor versus Clopidogrel with outcome assessment on MRI (PR...
    Medical condition: Carotid artery stenting (CAS) is treatment for atherosclerotic carotid stenosis. The main adverse events are thromboembolic brain infarcts during the procedure. Ticagrelor, a novel reversible inhib...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) NL (Completed) GB (GB - no longer in EU/EEA) BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000842-11 Sponsor Protocol Number: 18-122 Start Date*: 2007-10-15
    Sponsor Name:Medical University of Graz
    Full Title: 99Tc labled Inliximab for evaluation of inflammatory activity in patients with inflammtory bowel disease (IBD)
    Medical condition: Inflammatory bowel disease Crohn´s disease Ulcerative colitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-007200-16 Sponsor Protocol Number: ISS T-002 Start Date*: 2008-06-13
    Sponsor Name:ISTITUTO SUPERIORE DI SANITA'
    Full Title: A Phase II randomized, open label, immunogenicity and safety trial of the vaccine based on the recombinant biologically active HIV-1 Tat protein in anti-Tat negative HIV-1 infected HAART-treated ad...
    Medical condition: HIV-1 infected subjects
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020161 HIV infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2020-005839-76 Sponsor Protocol Number: PDE5I-UPR-AAR-01 Start Date*: 2021-02-15
    Sponsor Name:University hospital Bispebjerg and Frederiksberg, Department of Clinical Pharmacology
    Full Title: Effects of single dose tadalafil on urethral and anal closure function and on urinary flow in healthy females: A randomised, controlled, double-blinded, two-period cross-over study
    Medical condition: Urinary stress incontinence and fecal incontinence
    Disease: Version SOC Term Classification Code Term Level
    22.0 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults Gender: Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2008-000083-17 Sponsor Protocol Number: NVI-245 Start Date*: 2008-03-19
    Sponsor Name:Nederlands Vaccin Instituut
    Full Title: Nasopharyngeal pneumococcal colonization data in infants at the age of 12, 18 and 24 months
    Medical condition: Pneumococcal carriership in children having previously received Prevenar vaccination (7-valent pneumococcal conjugate vaccine) according to the 3+1 vaccination schedule used in the Dutch National I...
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: View results
    EudraCT Number: 2021-001465-20 Sponsor Protocol Number: FMLD-ARSIDOS-48 Start Date*: 2022-02-11
    Sponsor Name:Laboratorios Farmalíder S.A.
    Full Title: A double-blind, multicenter, randomized clinical trial to assess the efficacy and safety of Montelukast in patients with erosive / inflammatory arthrosis of the hands
    Medical condition: Erosive / inflammatory arthrosis of the hands
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10003416 Arthrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Temporarily Halted)
    Trial results: (No results available)
    EudraCT Number: 2006-004255-38 Sponsor Protocol Number: cnp-MS-0601/MC-2006-01 Start Date*: 2007-01-05
    Sponsor Name:Bionorica research GmbH
    Full Title: Multi-centre, randomized, double-blind, placebo-controlled study to investigate the efficacy and safety of the pain relieving effect of Dronabinol in patients with multiple sclerosis associated wit...
    Medical condition: Patients with multiple sclerosis associated with central neuropathic pain
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004852 10054095 Neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) DK (Prematurely Ended) DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-015955-25 Sponsor Protocol Number: 1/09 Start Date*: 2010-02-01
    Sponsor Name:University Hospital
    Full Title: INDIVIDUAL 5-FLUOROURACIL DOSE INDIVIDUALIZATION IN PATIENTS WITH COLORECTAL CANCER
    Medical condition: colorectal cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2007-005437-11 Sponsor Protocol Number: 06-API-07 Start Date*: 2009-10-05
    Sponsor Name:CHU de NICE
    Full Title: Arthrose érosive des doigts : traitement par méthotrexate versus placebo- évaluation de l’action clinique et structurale (IRM dédiée)- Etude ADEM
    Medical condition: ARTHROSE DIGITALE
    Disease: Version SOC Term Classification Code Term Level
    12.0 10031199 Osteoarthrosis, localized, primary, involving hand LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: View results
    EudraCT Number: 2010-021036-33 Sponsor Protocol Number: P-AG-E-3 Start Date*: 2011-02-04
    Sponsor Name:Bionorica SE
    Full Title: Double-blind comparison of VAC BNO 1095 FCT with placebo to identify dose dependent effects in patients suffering from cyclic mastodynia and PMS
    Medical condition: cyclic mastodynia and PMS
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2012-005042-37 Sponsor Protocol Number: P-AG-E-4 Start Date*: 2013-05-10
    Sponsor Name:Bionorica SE
    Full Title: Prospective, double-blind, placebo-controlled, parallel-group, multi-centre randomized clinical trial to proof efficacy and safety of 20 mg (2 tablets of 10 mg) VAC BNO 1095 FCT in patients sufferi...
    Medical condition: Cyclic mastodynia and PMS
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: DE (Prematurely Ended) PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-001382-28 Sponsor Protocol Number: INCB 18424-256 Start Date*: 2008-09-19
    Sponsor Name:Incyte Corporation
    Full Title: A Phase 2, open label, dose regimen ranging clinical study to determine the safety and efficacy of INCB018424 in patients with advanced polycythemia vera or essential thrombocythemia refractory ...
    Medical condition: advanced polycythemia vera or essential thrombocythemia refractory to hydroxyurea
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036057 Polycythaemia vera LLT
    9.1 10015494 Essential thrombocythemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-003926-11 Sponsor Protocol Number: MVDV 07/2007 Start Date*: 2007-10-03
    Sponsor Name:University Hospitals Leuven
    Full Title: Low dose of ephedrine versus phenylephrine in the prevention of arterial hypotension after low dosed CSE for elective C-section : is there a difference in umbilical blood gas values ?
    Medical condition: combined spinal-epidural analgesia during C-section
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2021-006068-26 Sponsor Protocol Number: FJD-MEIC-21-01 Start Date*: 2022-07-27
    Sponsor Name:FUNDACION JIMENEZ DIAZ HEALTH RESEARCH INSTITUTE
    Full Title: CLINICAL TRIAL PHASE IIa TO EVALUATE THE SAFETY AND EFFECTIVENESS OF TREATMENT WITH FAT-DERIVED MESENCHYMAL ALLOGENIC MESENCHYMAL TRONCAL CELLS IN PATIENTS WITH SINGLE INFLAMMATORY STENOSIS IN THE ...
    Medical condition: Inflammatory stenosis in patient with Crohn's disease.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-006975-41 Sponsor Protocol Number: URONCOR06-24 Start Date*: 2022-07-27
    Sponsor Name:GICOR
    Full Title: Short versus long-term androgen deprivation therapy combined with salvage radiotherapy in prostate cancer patients with biochemical recurrence after prostatectomy: a multicentre phase III randomise...
    Medical condition: Short versus long-term androgen deprivation therapy combined with salvage radiotherapy in prostate cancer patients with biochemical recurrence after prostatectomy
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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