- Trials with a EudraCT protocol (81)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
81 result(s) found for: Epidermal cells.
Displaying page 3 of 5.
EudraCT Number: 2018-004457-24 | Sponsor Protocol Number: PREDIX-II-HER2 | Start Date*: 2019-03-06 |
Sponsor Name:Karolinska University Hospital | ||
Full Title: PREDIX II HER2. Improving pre-operative systemic therapy for human epidermal growth factor receptor 2 (HER2) amplified breast cancer Part of a platform of translational phase 2 trials based on mole... | ||
Medical condition: Primary breast cancer | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Female | |
Trial protocol: SE (Prematurely Ended) | ||
Trial results: (No results available) |
EudraCT Number: 2011-002564-24 | Sponsor Protocol Number: B490 | Start Date*: 2011-10-14 | |||||||||||
Sponsor Name:ISTITUTO NAZIONALE PER LA CURA TUMORI | |||||||||||||
Full Title: Cetuximab and Cisplatin with or without Paclitaxel in recurrent/metastatic head and neck cancer | |||||||||||||
Medical condition: Recurrent/metastatic head and neck squamous cell carcinoma | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2017-004897-32 | Sponsor Protocol Number: WO40324 | Start Date*: 2018-06-04 | |||||||||||
Sponsor Name:F. Hoffmann-La Roche Ltd. | |||||||||||||
Full Title: A phase III, randomized, multicenter, open-label, two-arm study to evaluate the pharmacokinetics, efficacy, and safety of subcutaneous administration of the fixed-dose combination of pertuzumab and... | |||||||||||||
Medical condition: Human epidermal growth factor receptor 2 (HER2)-positive Early Breast Cancer. | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) DE (Completed) ES (Ongoing) BE (Completed) CZ (Completed) PL (Completed) IT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2019-002488-91 | Sponsor Protocol Number: MO39874 | Start Date*: 2019-11-04 | |||||||||||
Sponsor Name:F. Hoffmann-La Roche Ltd | |||||||||||||
Full Title: AN OPEN-LABEL, PHASE IIIB, SINGLE ARM, MULTICENTER STUDY OF ATEZOLIZUMAB (TECENTRIQ) PLUS NAB-PACLITAXEL IN THE TREATMENT OF UNRESECTABLE LOCALLY ADVANCED OR METASTATIC PD-L1-POSITIVE TRIPLE-NEGATI... | |||||||||||||
Medical condition: Unresectable locally advanced or metastatic triple-negative breast cancer (TNBC) | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: PT (Completed) SI (Completed) FR (Completed) HU (Completed) SK (Prematurely Ended) IT (Completed) RO (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2018-000519-26 | Sponsor Protocol Number: 8951-CL-0302 | Start Date*: 2019-02-13 | |||||||||||
Sponsor Name:Astellas Pharma Global Development, Inc. (APGD) | |||||||||||||
Full Title: A Phase 3, Global, Multi-Center, Double-Blind, Randomized, Efficacy Study of Zolbetuximab (IMAB362) Plus CAPOX Compared with Placebo Plus CAPOX as First-line Treatment of Subjects with Claudin (CLD... | |||||||||||||
Medical condition: Claudin (CLDN)18.2-Positive, HER2-Negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IE (Completed) NL (Completed) ES (Restarted) AT (Prematurely Ended) PT (Trial now transitioned) GR (Completed) GB (GB - no longer in EU/EEA) DE (Prematurely Ended) HR (Completed) RO (Trial now transitioned) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2006-003568-73 | Sponsor Protocol Number: GECP06/01 | Start Date*: 2008-05-07 | |||||||||||
Sponsor Name:Grupo Espagnol de Cancer de Pulmon | |||||||||||||
Full Title: Phase III, Multicenter, Open-label, Randomized Study of Erlotinib (Tarceva®) Treatment Versus Chemotherapy in Patients with Advanced Non-small-cell Carcinoma of the Lung Who Present Mutations in th... | |||||||||||||
Medical condition: Non-squamous-cell, non-small-cell lung cancer in stage IIIB and IV | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: FR (Completed) IT (Prematurely Ended) ES (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2012-003638-18 | Sponsor Protocol Number: AG0112CR | Start Date*: 2013-03-13 |
Sponsor Name:Australasian Gastro-Intestinal Trials Group, Sydney University | ||
Full Title: Randomised Phase II study of cetuximab alone or in combination with irinotecan in patients with metastatic CRC with either KRAS WT or G13D mutation. ICE CREAM: The Irinotecan Cetuximab Evaluation a... | ||
Medical condition: metastatic colorectal cancer | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: GB (GB - no longer in EU/EEA) ES (Completed) IT (Completed) BE (Completed) | ||
Trial results: (No results available) |
EudraCT Number: 2006-000871-13 | Sponsor Protocol Number: EMD72000-035 | Start Date*: 2006-08-09 | |||||||||||
Sponsor Name:Merck KGaA | |||||||||||||
Full Title: A Phase I/II, Open Label, Dose-Escalating Study Evaluating the Safety and Efficacy of the Anti-Epidermal Growth Factor Receptor (EGFR) Monoclonal Antibody EMD 72000 (Matuzumab) in Combination with ... | |||||||||||||
Medical condition: Stage IIIB/IV non-small cell lung cancer and progressive disease after first-line treatment with a platinum analogue in comination with taxanes, gemcitabine, or vinorelbine | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2019-002123-15 | Sponsor Protocol Number: GEICAM/2019-01 | Start Date*: 2020-06-15 | |||||||||||
Sponsor Name:GEICAM (Fundación Grupo Español de Investigación en Cáncer de Mama) | |||||||||||||
Full Title: Phase II, randomized, open-label, international, multicenter study to compare efficacy of standard chemotherapy vs. letrozole plus abemaciclib as neoadjuvant therapy in HR-positive/HER2-negative hi... | |||||||||||||
Medical condition: High/intermediate risk hormone receptor (HR) positive/human epidermal growth factor receptor 2 (HER2) negative breast cancer patients with indication of neoadjuvant therapy | |||||||||||||
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Population Age: Adults, Elderly | Gender: Female | ||||||||||||
Trial protocol: ES (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2019-001923-11 | Sponsor Protocol Number: 18-BI-1206-03 | Start Date*: 2019-12-09 | |||||||||||
Sponsor Name:BioInvent International AB | |||||||||||||
Full Title: Phase 1/2a Clinical Trial of BI-1206, a Monoclonal Antibody to CD32b (FcγRIIB), in Combination with Pembrolizumab in Subjects with Advanced Solid Tumors Previously Treated with Anti-PD1 or Anti-PDL... | |||||||||||||
Medical condition: Advanced solid tumors who have relapsed or are refractory to anti-PD1 or anti-PDL1 therapy. | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: SE (Trial now transitioned) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2022-002485-32 | Sponsor Protocol Number: CTRIAL-IE-22-01 | Start Date*: 2023-03-07 | |||||||||||
Sponsor Name:Cancer Trials Ireland | |||||||||||||
Full Title: Single arm phase 2 trial of neoadjuvant trastuzumab deruxtecan (T-DXd) with response-directed definitive therapy in early stage HER2-positive breast cancer: a standard chemotherapy-sparing approach... | |||||||||||||
Medical condition: HER2-positive breast cancer. | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IE (Trial now transitioned) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2013-000093-29 | Sponsor Protocol Number: 9785-CL-1121 | Start Date*: 2014-06-02 | |||||||||||||||||||||
Sponsor Name:Astellas Pharma Global Development, Inc. | |||||||||||||||||||||||
Full Title: A Phase 2, Multicenter, Open-label Study to Assess the Efficacy and Safety of Enzalutamide with Trastuzumab in Subjects with HER2+ AR+ Metastatic or Locally Advanced Breast Cancer | |||||||||||||||||||||||
Medical condition: Subjects with HER2+ AR+ Metastatic or Locally Advanced Breast Cancer | |||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Female | ||||||||||||||||||||||
Trial protocol: BE (Completed) GB (GB - no longer in EU/EEA) ES (Completed) IT (Completed) | |||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2016-004024-29 | Sponsor Protocol Number: MO39196 | Start Date*: 2017-06-15 | |||||||||||
Sponsor Name:F. Hoffmann-La Roche Ltd | |||||||||||||
Full Title: A PHASE III, MULTICENTER, RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF ATEZOLIZUMAB (ANTI−PD-L1 ANTIBODY) IN COMBINATION WITH PACLITAXEL COMPARED WITH PLACEBO WITH PACLITAXEL FOR PATIENTS ... | |||||||||||||
Medical condition: Triple Negative Breast Cancer (TNBC) | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: SK (Completed) DE (Completed) CZ (Completed) GB (GB - no longer in EU/EEA) GR (Completed) FR (Completed) ES (Ongoing) HR (Completed) IT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2007-005939-28 | Sponsor Protocol Number: BO21495 | Start Date*: 2008-04-29 | ||||||||||||||||
Sponsor Name:F. Hoffmann-La Roche Ltd | ||||||||||||||||||
Full Title: Estudio de fase I/II multicéntrico, abierto, de escalada de dosis, para evaluar la seguridad, farmacocinética y actividad de RO5083945, un anticuerpo glico-modificado anti-EGFR, en pacientes con tu... | ||||||||||||||||||
Medical condition: Parte I: Tumores sólidos malignos metastáticos y/o localmente avanzados que expresan el receptor del factor de crecimiento endotelial (EGFR) Parte II: Cáncer colorrectal metastático o localmente a... | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: ES (Completed) FR (Completed) | ||||||||||||||||||
Trial results: View results |
EudraCT Number: 2015-002197-21 | Sponsor Protocol Number: D419AC00003 | Start Date*: 2016-02-19 | |||||||||||
Sponsor Name:AstraZeneca AB | |||||||||||||
Full Title: A Phase III Randomized, Open-Label, Multi-Center, Global Study of MEDI4736 in Combination with Tremelimumab Therapy Versus Standard of Care Platinum-Based Chemotherapy in First-Line Treatment of Pa... | |||||||||||||
Medical condition: Advanced or Metastatic Non Small Cell Lung Cancer (NSCLC) in treatment naive patients with epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) wild type tumour pathology. | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: BG (Completed) GB (GB - no longer in EU/EEA) FI (Completed) SE (Completed) PL (Completed) PT (Completed) GR (Completed) DK (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2018-004211-42 | Sponsor Protocol Number: POL6326-009 | Start Date*: 2020-03-06 | ||||||||||||||||
Sponsor Name:Polyphor Ltd. | ||||||||||||||||||
Full Title: An International, Phase 3, Multicenter, Randomized, Open-Label Trial Comparing Balixafortide in combination with Eribulin versus Eribulin alone in Patients with HER2 negative, Locally Recurrent or ... | ||||||||||||||||||
Medical condition: Patients with HER2 negative, Locally Recurrent or Metastatic Breast Cancer | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: CZ (Prematurely Ended) GB (GB - no longer in EU/EEA) DE (Prematurely Ended) ES (Prematurely Ended) BE (Prematurely Ended) IT (Prematurely Ended) | ||||||||||||||||||
Trial results: View results |
EudraCT Number: 2018-001213-32 | Sponsor Protocol Number: MedOPP168 | Start Date*: 2019-02-04 | |||||||||||
Sponsor Name:Medica Scientia Innovation Research (MedSIR) | |||||||||||||
Full Title: Effectiveness of olaparib plus trastuzumab in HER2-positive BRCA-mutated or Homologous Recombination Deficiency (HRD) advanced breast cancer patients – The OPHELIA Study – | |||||||||||||
Medical condition: HER2-positive BRCAmutated or Homologous Recombination Deficiency (HRD) advanced breast cancer | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2015-004189-27 | Sponsor Protocol Number: WO30085 | Start Date*: 2016-10-21 | |||||||||||||||||||||
Sponsor Name:F. Hoffmann-La Roche Ltd | |||||||||||||||||||||||
Full Title: A RANDOMIZED, MULTICENTER, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE II STUDY OF THE EFFICACY AND SAFETY OF TRASTUZUMAB EMTANSINE IN COMBINATION WITH ATEZOLIZUMAB OR ATEZOLIZUMAB-PLACEBO IN PATIENTS W... | |||||||||||||||||||||||
Medical condition: Unresectable locally advanced or metastatic breast cancer (MBC). | |||||||||||||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||||||||||||
Trial protocol: DE (Prematurely Ended) ES (Completed) GB (Completed) IT (Completed) | |||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2018-002153-30 | Sponsor Protocol Number: MO40628 | Start Date*: 2018-10-24 | |||||||||||
Sponsor Name:Roche Farma S.A.(Soc Uni) que realiza el ensayo en España y que actúa como representante de F. Hoffmann-La Roche Ltd. | |||||||||||||
Full Title: A randomized, multicenter, open-label cross-over study to evaluate patient preference and satisfaction of subcutaneous administration of the fixed-dose combination of pertuzumab and trastuzumab in ... | |||||||||||||
Medical condition: Human epidermal growth factor receptor 2 (HER2)-positive Early Breast Cancer. | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Completed) PT (Completed) SE (Completed) FI (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2020-005722-28 | Sponsor Protocol Number: 2020/3188 | Start Date*: 2021-04-29 | |||||||||||
Sponsor Name:Gustave Roussy | |||||||||||||
Full Title: Phase 2, Open label Study of Patritumab Deruxtecan (U3-1402), an Anti-HER3-Antibody Drug Conjugate (ADC), in patients with Advanced Breast Cancer, with biomarker analyses to characterize response t... | |||||||||||||
Medical condition: Patients with human epidermal growth factor receptor 3-overexpressing (HER3-high) and hormone-receptor positive (HR+) advanced breast cancer who have already received standard therapy for HR+ advan... | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: FR (Trial now transitioned) | |||||||||||||
Trial results: (No results available) |
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