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Clinical trials for Total Knee Replacement

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    The EU Clinical Trials Register currently displays   44346   clinical trials with a EudraCT protocol, of which   7374   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    107 result(s) found for: Total Knee Replacement. Displaying page 5 of 6.
    « Previous 1  2  3  4  5  6  Next»
    EudraCT Number: 2016-004550-15 Sponsor Protocol Number: 64179375THR2001 Start Date*: 2017-10-11
    Sponsor Name:Janssen-Cilag International NV
    Full Title: A Randomized, Double-blind, Double-dummy, Multicenter, Adaptive Design Dose-Escalation (Part 1) and Dose-Response (Part 2) Study to Evaluate the Safety and Efficacy of Intravenous JNJ-64179375 Vers...
    Medical condition: Thromboembolism in subjects who have undergone an elective primary unilateral total knee replacement
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) ES (Completed) PL (Completed) LV (Completed) LT (Prematurely Ended) BG (Completed) GR (Completed) PT (Completed) IT (Completed) RO (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-005069-30 Sponsor Protocol Number: UG1_2016 Start Date*: 2017-02-28
    Sponsor Name:Pia Jæger
    Full Title: Comparison of the analgesic effect of an adductor canal block using a new suture-method catheter vs a standard perineural catheter vs a single bolus: A randomized, blinded, controlled study
    Medical condition: Primary total knee arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004865 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2018-004237-32 Sponsor Protocol Number: 70033093THR2001 Start Date*: 2019-08-05
    Sponsor Name:Janssen-Cilag International NV
    Full Title: A Randomized, Open-Label, Study Drug-Dose Blind, Multicenter Study to Evaluate the Efficacy and Safety of JNJ-70033093 (BMS-986177), an Oral Factor XIa Inhibitor, Versus Subcutaneous Enoxaparin in ...
    Medical condition: Thromboembolism in subjects who have undergone an elective primary unilateral total knee replacement
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004866 10066899 Venous thromboembolism LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) HU (Completed) PL (Completed) PT (Completed) BG (Completed) ES (Completed) GR (Completed) LT (Prematurely Ended) IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-016337-10 Sponsor Protocol Number: KF10004/08 Start Date*: 2010-04-26
    Sponsor Name:Grünenthal GmbH
    Full Title: Lidocaine 5% medicated plaster for the topical treatment of localized chronic postoperative neuropathic pain after total knee replacement or thoracotomy
    Medical condition: localized chronic post-operative neuropathic pain (PoNP) after total knee replacement or thoracotomy (including drainage, excluding subjects with neoplasia-related thoracotomy)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10054095 Neuropathic pain LLT
    12.1 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2016-002681-31 Sponsor Protocol Number: BAY1213790/17664 Start Date*: 2017-07-13
    Sponsor Name:Bayer AG
    Full Title: A randomized, active-comparator-controlled, multicenter study to assess the safety and efficacy of different doses of BAY 1213790 for the prevention of venous thromboembolism in patients undergoing...
    Medical condition: Prevention of venous thromboembolism
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10049909 Venous thromboembolism prophylaxis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) LT (Completed) CZ (Completed) DE (Completed) LV (Completed) BG (Completed) PL (Completed) GR (Completed) PT (Completed)
    Trial results: View results
    EudraCT Number: 2017-002925-39 Sponsor Protocol Number: CMAA868A2201 Start Date*: 2018-02-23
    Sponsor Name:Novartis Farmacéutica, S.A.
    Full Title: A multicenter, randomized, open-label, blinded endpoint evaluation, active-controlled Phase 2 study to compare the efficacy and safety of s.c. MAA868 versus s.c. enoxaparin in adult patients underg...
    Medical condition: venous thromboembolism
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004866 10066899 Venous thromboembolism LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended) AT (Prematurely Ended) CZ (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-004285-15 Sponsor Protocol Number: SM2-PJ-11 Start Date*: 2011-09-22
    Sponsor Name:Professor Jørgen Berg Dahl
    Full Title: A comparison of the efficacy of the Adductor-Canal-Blockade vs. the femoral nerve block on muscle strength and mobilization in healthy volunteers: a randomized study
    Medical condition: Healthy volunteers (intended for postoperative pain treatment in patients after total knee arthroplasty)
    Disease: Version SOC Term Classification Code Term Level
    14.0 10022117 - Injury, poisoning and procedural complications 10054711 Postoperative pain LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2008-004539-39 Sponsor Protocol Number: TB-402-004 Start Date*: 2008-12-19
    Sponsor Name:ThromboGenics N.V
    Full Title: Single Intravenous Administration of TB-402 for the Prophylaxis of Venous hromboembolic Events (VTE) After Total Knee Replacement Surgery: A Dose-Escalating, Multicenter, Randomised, Active-Control...
    Medical condition: Venous thrombolic events
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049909 Venous thromboembolism prophylaxis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LV (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2016-003078-41 Sponsor Protocol Number: MUC-2/16 Start Date*: 2018-11-23
    Sponsor Name:MUCOS Pharma CZ s.r.o.
    Full Title: Reduction of post-traumatic systemic inflammatory response by Phlogenzym® using total hip replacement as a model.
    Medical condition: Total hip replacement
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-005495-34 Sponsor Protocol Number: A4091059 Start Date*: 2016-01-25
    Sponsor Name:Pfizer Inc, 235 East 42nd Street, New York, NY 10017
    Full Title: A PHASE 3, RANDOMIZED, DOUBLE BLIND, PLACEBO AND ACTIVE-CONTROLLED, MULTICENTER, PARALLEL-GROUP STUDY OF THE ANALGESIC EFFICACY AND SAFETY OF TANEZUMAB IN ADULT SUBJECTS WITH CHRONIC LOW BACK PAIN
    Medical condition: CHRONIC LOW BACK PAIN
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004859 10024891 Low back pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) HU (Completed) DK (Prematurely Ended) ES (Completed)
    Trial results: View results
    EudraCT Number: 2012-001249-41 Sponsor Protocol Number: KEK-ZH-2012-0249 Start Date*: 2013-04-12
    Sponsor Name:University Hospital of Zurich and City Hospital Waid
    Full Title: Vitamin D3 – Omega3 – Home Exercise – HeALTHy Ageing and Longevity Trial Randomized, double-blind, placebo-controlled, multi-centre clinical trial
    Medical condition: healthy ageing, functional decline
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing) PT (Completed) FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005802-29 Sponsor Protocol Number: RD/505/06 Start Date*: 2007-06-26
    Sponsor Name:Gwent Healthcare NHS Trust
    Full Title: Postoperative analgesia for Total knee replacement: A comparision between intrathecal morphine and peripheral nerve block.
    Medical condition: Postoperative analgesia for Total Knee Replacement
    Disease: Version SOC Term Classification Code Term Level
    14.0 10007541 - Cardiac disorders 10007521 Cardiac arrhythmias HLGT
    14.0 10022117 - Injury, poisoning and procedural complications 10029177 Nerve damage LLT
    14.0 10029205 - Nervous system disorders 10010914 Convulsions LLT
    14.0 10038738 - Respiratory, thoracic and mediastinal disorders 10038678 Respiratory depression PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-002955-40 Sponsor Protocol Number: 69HCL20_0111 Start Date*: 2020-08-12
    Sponsor Name:Hospices Civils de Lyon
    Full Title: Postoperative analgesic effect of orally administrated nefopam after a total knee arthroplasty: a randomized controlled trial
    Medical condition: Major patients who have a surgery in the orthopedic surgery department of the Croix Rousse hospital for a total knee replacement.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10042613 Surgical and medical procedures SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-004514-40 Sponsor Protocol Number: KF5503/33-R331333-PAI-3002 Start Date*: 2007-02-14
    Sponsor Name:Johnson & Johnson Pharamceutical Research & Development, L.L.C.
    Full Title: A Randomized, Double-Blind, Active- And Placebo-Controlled, Parallel Group, Multicenter Study To Evaluate The Efficacy And Safety of Multiple Doses of CG5503 Immediate Release Formulation In Subjec...
    Medical condition: Pain
    Disease: Version SOC Term Classification Code Term Level
    8.1 10033371 Pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-004986-15 Sponsor Protocol Number: Protocol_AFCN_17022019 Start Date*: 2019-02-18
    Sponsor Name:Aarhus University Hospital
    Full Title: Ultrasound-guided nerve block of the anterior femoral cutaneous nerves in healthy volunteers
    Medical condition: Pain around the surgical incision after total knee arthroplasty (TKA). The area anesthetized by a combination of nerve block techniques anesthetizing the anterior femoral cutaneous nerves are inve...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10036236 Postoperative pain relief LLT
    20.0 100000004865 10002325 Anesthesia local LLT
    20.1 10022891 - Investigations 10045434 Ultrasound scan PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2013-002223-42 Sponsor Protocol Number: A4091061 Start Date*: 2015-10-12
    Sponsor Name:Pfizer Inc, 235 East 42nd Street, New York, NY 10017
    Full Title: A PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY OF THE ANALGESIC EFFICACY AND SAFETY OF THE SUBCUTANEOUS ADMINISTRATION OF TANEZUMAB (PF-04383119) IN SUBJECTS WITH CANCER ...
    Medical condition: Metastatic Bone Pain
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10049038 Metastatic bone pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) CZ (Completed) GB (GB - no longer in EU/EEA) PL (Completed) ES (Completed) SK (Completed) HU (Completed) RO (Completed) FR (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-004601-32 Sponsor Protocol Number: SM4-UG-14 Start Date*: 2015-01-07
    Sponsor Name:Gentofte Hospital
    Full Title: The Effect of Local Anesthetic Volume within the Adductor Canal on Quadriceps Function Evaluated by Electromyography: A Randomized, Observer-Masked, Placebo-Controlled Study in Volunteers.
    Medical condition: Healthy volunteers. Results will be used for optimizing the treatment of post-operative pain after total knee arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    17.1 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-001439-30 Sponsor Protocol Number: ALS-Gd64/001 Start Date*: 2013-03-22
    Sponsor Name:Navitas Life Sciences GmbH
    Full Title: Exploratory evaluation of the potential for long-term retention of Gadolinium in the bones of patients who have received Gadolinium based Contrast Agents according to their medical history.
    Medical condition: Retention of gadolinium/traces of metals/minerals to be determined in bone/skin specimens and evaluation of signs of nephrogenic systemic fibrosis in skin.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Prematurely Ended) PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001709-10 Sponsor Protocol Number: P170924J Start Date*: 2018-10-30
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: I-MICRO: Ilomedine in the treatment of septic shock with persistence of microperfusion disorders: Multicenter randomized and controlled double-blind study.
    Medical condition: Ilomedin: Cardiology - Angeiology - Vasodilators and anti-ischemic drugs: Severe ischemia: route of injection (Prostaglandin analogs: iloprost)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040070 Septic shock PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005179-14 Sponsor Protocol Number: A5571010 Start Date*: 2006-06-02
    Sponsor Name:PFIZER, S.A.
    Full Title: A Phase 2B, Randomized, Multicenter, Dose-Ranging Study Assessing the Safety and Efficacy of PD 0348292 in the Prevention of Venous Thromboembolic Events (VTE) in Subjects Undergoing an Elective, U...
    Medical condition: Prevention of Venous Thromboembolic Events
    Disease: Version SOC Term Classification Code Term Level
    8.0 10014523 HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) DK (Completed) CZ (Completed) PT (Completed) SK (Completed) AT (Prematurely Ended) IT (Completed) GB (Completed)
    Trial results: View results
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