- Trials with a EudraCT protocol (21)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
21 result(s) found for: Immunofluorescence Microscopy.
Displaying page 1 of 2.
| EudraCT Number: 2016-002790-35 | Sponsor Protocol Number: C12-48 | Start Date*: 2019-06-04 | |||||||||||
| Sponsor Name:INSERM | |||||||||||||
| Full Title: Phase I/II ex vivo gene therapy clinical trial for RDEB using autologous skin equivalent grafts genetically corrected with a COL7A1-encoding SIN retroviral vector | |||||||||||||
| Medical condition: The trial aims to treat the recessive dystrophic epidermolysis bullosa (RDEB) by grafting one to three subjects with RDEB with autologous COL7A1-modified skin equivalents, using SIN-RV encoding COL... | |||||||||||||
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| Population Age: Adults | Gender: Male, Female | ||||||||||||
| Trial protocol: FR (Trial now transitioned) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2005-002391-14 | Sponsor Protocol Number: SAWV1003 | Start Date*: 2005-09-29 |
| Sponsor Name:Moorfields Eye Hospital NHS Foundation Trust | ||
| Full Title: Pulsed Intravenous Methylprednisolone for Ocular Pemphigoid- A Pilot Study | ||
| Medical condition: ocular mucous membrane pemphigoid | ||
| Disease: | ||
| Population Age: Adults, Elderly | Gender: Male, Female | |
| Trial protocol: GB (Completed) | ||
| Trial results: View results | ||
| EudraCT Number: 2016-005141-23 | Sponsor Protocol Number: 021FSGS16010 | Start Date*: 2018-09-18 | |||||||||||
| Sponsor Name:Retrophin, Inc. | |||||||||||||
| Full Title: A Randomized, Multicenter, Double-blind, Parallel, Active-control Study of the Effects of Sparsentan, a Dual Endothelin Receptor and Angiotensin Receptor Blocker, on Renal Outcomes in Patients with... | |||||||||||||
| Medical condition: Focal segmental glomerulosclerosis (FSGS) | |||||||||||||
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| Population Age: Children, Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: GB (GB - no longer in EU/EEA) DE (Trial now transitioned) CZ (Trial now transitioned) FR (Trial now transitioned) ES (Ongoing) PL (Trial now transitioned) HU (Prematurely Ended) DK (Trial now transitioned) EE (Trial now transitioned) SE (Trial now transitioned) PT (Trial now transitioned) BE (Trial now transitioned) HR (Trial now transitioned) IT (Trial now transitioned) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2005-003610-15 | Sponsor Protocol Number: RITUXVAS | Start Date*: 2005-12-15 |
| Sponsor Name:Cambridge University Hospitals NHS Foundation Trust | ||
| Full Title: An international, randomised, open trial comparing a rituximab based regimen with a standard cyclophosphamide/azathioprine regimen in the treatment of 'generalised' ANCA associated vasculitis. | ||
| Medical condition: Anti neutophil cytoplasmic antibody (ANCA) associated vasculitis | ||
| Disease: | ||
| Population Age: Adults, Elderly | Gender: Male, Female | |
| Trial protocol: GB (Completed) CZ (Completed) SE (Completed) | ||
| Trial results: View results | ||
| EudraCT Number: 2014-004884-19 | Sponsor Protocol Number: LENTICOL-F | Start Date*: 2016-05-24 | |||||||||||
| Sponsor Name:King's College London [...] | |||||||||||||
| Full Title: Phase I study of lentiviral-mediated COL7A1 gene-modified autologous fibroblasts in adults with recessive dystrophic epidermolysis bullosa (RDEB) | |||||||||||||
| Medical condition: Recessive Dystrophic Epidermolysis Bullosa | |||||||||||||
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| Population Age: Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
| Trial protocol: GB (Completed) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2017-004806-17 | Sponsor Protocol Number: PQ-313-002 | Start Date*: 2018-05-18 | |||||||||||
| Sponsor Name:Wings Therapeutics Inc. | |||||||||||||
| Full Title: A first in human, double-blind, randomized, intra-subject placebo-controlled, multiple dose study of QR-313 evaluating safety, proof of mechanism, preliminary efficacy and systemic exposure in subj... | |||||||||||||
| Medical condition: Recessive Dystrophic Epidermolysis Bullosa (RDEB) due to mutation(s) in exon 73 of the COL7A1 gene | |||||||||||||
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| Population Age: Children, Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
| Trial protocol: GB (GB - no longer in EU/EEA) FR (Prematurely Ended) DE (Prematurely Ended) CZ (Completed) ES (Prematurely Ended) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2018-003437-15 | Sponsor Protocol Number: P170922J | Start Date*: 2019-04-03 | |||||||||||
| Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS | |||||||||||||
| Full Title: Rituximab from the FIRst Episode of Idiopathic Nephrotic Syndrome | |||||||||||||
| Medical condition: Minimal Change Nephrotic Syndrome (MCNS) | |||||||||||||
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| Population Age: Adults | Gender: Male, Female | ||||||||||||
| Trial protocol: FR (Trial now transitioned) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2020-002936-55 | Sponsor Protocol Number: MSC-EB_2020 | Start Date*: 2021-08-11 |
| Sponsor Name:Masarykova univerzita | ||
| Full Title: Safety and Efficacy of Allogenic Adipose Tissue-derived Mesenchymal Stromal Cells in Patients with Epidermolysis Bullosa: Clinical Trial Phase I/II | ||
| Medical condition: Epidermolysis bullosa congenita | ||
| Disease: | ||
| Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults | Gender: Male, Female | |
| Trial protocol: CZ (Trial now transitioned) | ||
| Trial results: (No results available) | ||
| EudraCT Number: 2012-000605-72 | Sponsor Protocol Number: CB+MSCforEB | Start Date*: 2014-02-06 |
| Sponsor Name:Universitair Medisch Centrum Utrecht | ||
| Full Title: Unrelated cord blood transplantation after reduced toxicity conditioning with mesenchymal stromal cell co-infusion in patients with severe epidermolysis bullosa | ||
| Medical condition: The source population consists of patients referred to or within the UMC Groningen because they have diagnosed clinically and genetically severe generalized RDEB. | ||
| Disease: | ||
| Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 | Gender: Male, Female | |
| Trial protocol: NL (Prematurely Ended) | ||
| Trial results: (No results available) | ||
| EudraCT Number: 2019-004254-28 | Sponsor Protocol Number: CAEL101-301 | Start Date*: 2021-01-07 | |||||||||||
| Sponsor Name:Caelum Biosciences, Inc. | |||||||||||||
| Full Title: A Phase 3, Double-Blind, Multicenter Study to Evaluate the Efficacy and Safety of CAEL-101 and Plasma Cell Dyscrasia Treatment Versus Placebo and Plasma Cell Dyscrasia Treatment in Plasma Cell Dysc... | |||||||||||||
| Medical condition: stage IIIb cardiac AL amyloidosis | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: FR (Trial now transitioned) DE (Trial now transitioned) GB (GB - no longer in EU/EEA) GR (Trial now transitioned) PL (Trial now transitioned) BE (Trial now transitioned) IT (Trial now transitioned) AT (Trial now transitioned) CZ (Trial now transitioned) NL (Completed) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2020-000713-32 | Sponsor Protocol Number: CAEL101-302 | Start Date*: 2021-02-09 | |||||||||||
| Sponsor Name:Caelum Biosciences, Inc. | |||||||||||||
| Full Title: A Phase 3, Double-Blind, Multicenter Study to Evaluate the Efficacy and Safety of CAEL-101 and Plasma Cell Dyscrasia Treatment Versus Placebo and Plasma Cell Dyscrasia Treatment in Plasma Cell Dysc... | |||||||||||||
| Medical condition: stage IIIa cardiac AL amyloidosis | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: FR (Trial now transitioned) DE (Trial now transitioned) GB (GB - no longer in EU/EEA) GR (Trial now transitioned) PL (Trial now transitioned) BE (Completed) IT (Trial now transitioned) AT (Trial now transitioned) CZ (Trial now transitioned) NL (Completed) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2017-001821-42 | Sponsor Protocol Number: CL011_168 | Start Date*: 2018-08-02 | |||||||||||
| Sponsor Name:ChemoCentryx, Inc. | |||||||||||||
| Full Title: A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study to Evaluate the Safety and Efficacy of Avacopan (CCX168) in Patients with C3 Glomerulopathy | |||||||||||||
| Medical condition: C3 glomerulopathy (C3G) is characterized by evidence of alternative complement activation based on C3 deposition in the glomeruli. There are two forms of the disease: dense deposit disease (DDD, fo... | |||||||||||||
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| Population Age: Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: GB (GB - no longer in EU/EEA) BE (Completed) DE (Completed) NL (Completed) ES (Completed) DK (Completed) FR (Completed) IT (Completed) IE (Completed) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2018-003682-34 | Sponsor Protocol Number: VKTX01 | Start Date*: 2019-10-23 |
| Sponsor Name:Vitaeris Inc. | ||
| Full Title: A Pivotal Phase 3 Trial to Evaluate the Safety and Efficacy of Clazakizumab for the Treatment of Chronic Active Antibody-Mediated Rejection in Kidney Transplant Recipients | ||
| Medical condition: Chronic Active Antibody-Mediated Rejection (CABMR) in Kidney Transplant Recipients | ||
| Disease: | ||
| Population Age: Adults, Elderly | Gender: Male, Female | |
| Trial protocol: CZ (Completed) HU (Prematurely Ended) BE (Completed) DE (Completed) NL (Completed) AT (Completed) ES (Prematurely Ended) | ||
| Trial results: View results | ||
| EudraCT Number: 2013-004664-58 | Sponsor Protocol Number: BESTCILIA-WP5 | Start Date*: 2014-08-26 | |||||||||||
| Sponsor Name:Paediatric Pulmonary Service, Department of Paediatrics and Adolescent Medicine, Rigshospitalet, Copenhagen, Denmark | |||||||||||||
| Full Title: RANDOMIZED CONTROLLED TRIAL (RCT) TO DETERMINE THE EFFICACY AND SAFETY OF AZITHROMYCIN (AZN) MAINTENANCE THERAPY FOR 6 MONTHS IN SUBJECTS WITH PCD - A DOUBLE-BLIND, PARALLEL GROUP STUDY | |||||||||||||
| Medical condition: Primary ciliary dyskinesia (PCD) | |||||||||||||
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| Population Age: Children, Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
| Trial protocol: DE (Prematurely Ended) DK (Prematurely Ended) GB (Prematurely Ended) NL (Prematurely Ended) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2017-000606-37 | Sponsor Protocol Number: MesenSistem-EB | Start Date*: 2017-11-16 |
| Sponsor Name:Fundación para la Investigación Biomédica Hospital Universitario La Paz | ||
| Full Title: Safety and preliminary efficacy study of infusing mesenchymal stem cells derived from bone marrow for treating Recessive Dystrophic Epidermolysis Bullosa. | ||
| Medical condition: Recessive Dystrophic Epidermolysis Bullosa | ||
| Disease: | ||
| Population Age: Children, Adolescents, Under 18 | Gender: Male, Female | |
| Trial protocol: ES (Ongoing) | ||
| Trial results: (No results available) | ||
| EudraCT Number: 2021-004174-64 | Sponsor Protocol Number: DMX-200-301 | Start Date*: 2022-03-08 | ||||||||||||||||
| Sponsor Name:Dimerix Bioscience Pty Ltd | ||||||||||||||||||
| Full Title: A pivotal Phase 3, multicenter, randomized, double-blind, placebo-controlled study of the efficacy and safety of DMX-200 in patients with focal segmental glomerulosclerosis (FSGS) who are receiving... | ||||||||||||||||||
| Medical condition: Focal segmental glomerulosclerosis | ||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
| Trial protocol: DK (Trial now transitioned) ES (Ongoing) FR (Trial now transitioned) | ||||||||||||||||||
| Trial results: (No results available) | ||||||||||||||||||
| EudraCT Number: 2018-003835-31 | Sponsor Protocol Number: IB2018-04 | Start Date*: 2021-09-28 | |||||||||||
| Sponsor Name:Institut Bergonié | |||||||||||||
| Full Title: Targeting ATR in soft-tissue sarcomas: a randomized phase II study. TARSARC study | |||||||||||||
| Medical condition: Locally advanced/unresectable and/or metastatic soft-tissue leiomyosarcomas | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: FR (Trial now transitioned) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2014-000382-41 | Sponsor Protocol Number: WA29330 | Start Date*: 2015-03-06 | |||||||||||
| Sponsor Name:F. Hoffmann-La Roche Ltd | |||||||||||||
| Full Title: A randomized, double-blind, double-dummy active-comparator, multicenter study to evaluate the efficacy and safety of rituximab versus MMF in patients with pemphigus vulgaris | |||||||||||||
| Medical condition: Pemphigus Vulgaris (PV) | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: DE (Completed) ES (Completed) IT (Completed) FR (Completed) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2015-003564-37 | Sponsor Protocol Number: PRN1008-005 | Start Date*: 2016-04-21 | |||||||||||
| Sponsor Name:Principia Biopharma Australia Pty Ltd | |||||||||||||
| Full Title: An Open-Label, Phase 2, Pilot Study Investigating the Safety, Clinical Activity, Pharmacokinetics, and Pharmacodynamics of Oral Treatment with the BTK Inhibitor PRN1008 in Patients with Newly Diagn... | |||||||||||||
| Medical condition: Pemphigus: Pemphigus Vulgaris | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: GR (Completed) HR (Completed) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2018-004253-24 | Sponsor Protocol Number: CLNP023B12001B | Start Date*: 2019-08-28 |
| Sponsor Name:Novartis Pharma AG | ||
| Full Title: An open-label, non-randomized extension study to evaluate the long-term efficacy, safety and tolerability of LNP023 in subjects with C3 glomerulopathy | ||
| Medical condition: C3 Glomerulopathy | ||
| Disease: | ||
| Population Age: Adults, Elderly | Gender: Male, Female | |
| Trial protocol: GB (GB - no longer in EU/EEA) IT (Trial now transitioned) FR (Trial now transitioned) ES (Ongoing) DE (Trial now transitioned) GR (Trial now transitioned) NL (Trial now transitioned) CZ (Trial now transitioned) | ||
| Trial results: (No results available) | ||
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