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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 2,177 of 2,219.
    EudraCT Number: 2016-000888-16 Sponsor Protocol Number: 16-001 Start Date*: 2018-05-17
    Sponsor Name:Medical University of Vienna
    Full Title: Bronchoscopic indocyanine green fluorescence imaging for the evaluation of anastomotic healing after lung transplantation
    Medical condition: Anastomotic healing after lung transplantation
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-004929-33 Sponsor Protocol Number: SiccaIkervis Start Date*: 2018-12-05
    Sponsor Name:KH Hietzing, Department of Ophthalmology
    Full Title: Effect of Ciclosporin eyedrops on ocular symptoms and optical image quality in patients with primary or secondary Sjögren syndrome
    Medical condition: primary or secondary Sjögren Syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-004494-27 Sponsor Protocol Number: 5020DERM-2018 Start Date*: Information not available in EudraCT
    Sponsor Name:Landeskrankenhaus Salzburg
    Full Title: pilotstudy- efficacy of infectoscab 5% creme in patients with scabies
    Medical condition: Scabies
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10039511 Scabies LLT
    20.0 10021881 - Infections and infestations 10063409 Acarodermatitis PT
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-000142-35 Sponsor Protocol Number: UC-0160/1105 Start Date*: 2014-05-19
    Sponsor Name:UNICANCER
    Full Title: A prospective randomised phase III study of androgen deprivation therapy with or without local radiotherapy with or without abiraterone acetate and prednisone in patient with metastatic hormone-na...
    Medical condition: metastatic hormone-naïve prostate cancer
    Disease: Version SOC Term Classification Code Term Level
    16.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10036909 Prostate cancer metastatic PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: FR (Completed) ES (Ongoing) IE (Completed) BE (Completed) IT (Completed) DE (Completed) RO (Completed) GR (Ongoing) PT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-000941-10 Sponsor Protocol Number: CLI24-001 Start Date*: 2020-07-02
    Sponsor Name:Menarini Ricerche S.p.A
    Full Title: A Phase I/II Study of SEL24 in Patients with Acute Myeloid Leukemia
    Medical condition: Acute Myeloid Leukemia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-003675-35 Sponsor Protocol Number: WV2018 Start Date*: 2018-11-01
    Sponsor Name:Karolinska Institutet
    Full Title: Efficacy of Very Early Medical Abortion – a randomized controlled non-inferiority trial
    Medical condition: Unwanted pregnancy
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: SE (Completed) FI (Completed) AT (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2016-002828-85 Sponsor Protocol Number: RG_15-114 Start Date*: 2017-04-28
    Sponsor Name:University of Birmingham
    Full Title: Paediatric Hepatic International Tumour Trial
    Medical condition: Hepatoblastoma and Hepatocellular Carcinoma.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10062001 Hepatoblastoma PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10019828 Hepatocellular carcinoma non-resectable LLT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10019830 Hepatocellular carcinoma resectable LLT
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) IE (Trial now transitioned) ES (Ongoing) NO (Trial now transitioned) DE (Ongoing) CZ (Trial now transitioned) BE (Trial now transitioned) FR (Trial now transitioned) NL (Trial now transitioned) PL (Trial now transitioned) AT (Trial now transitioned) SE (Completed) FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002055-10 Sponsor Protocol Number: PURE-01 Start Date*: 2020-07-06
    Sponsor Name:Fondazione IRCCS Istituto Nazionale dei Tumori
    Full Title: PURE-01 – An open label, single-arm, phase 2 study of neoadjuvant pembrolizumab (MK-3475) before cystectomy for patients with muscle-invasive urothelial bladder cancer.
    Medical condition: muscle-invasive urothelial bladder cancer
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: AT (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-004319-37 Sponsor Protocol Number: 001.4 Start Date*: 2019-06-19
    Sponsor Name:Medical University of Vienna, Department of Surgery
    Full Title: A prospective, randomised, single-blind explorative study to investigate the efficacy and safety of fat graft enrichment with autologous platelet lysate in female breast augmentation
    Medical condition: Fat grafting e.g. to the breast to restore small tissue defects is a very common and safe surgical procedure. Its main success among other is depended on the survival rate of the transferred fat ti...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10018065 - General disorders and administration site conditions 10016251 Fat tissue increased PT
    Population Age: Adults Gender: Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001340-22 Sponsor Protocol Number: CathLockTrialHD Start Date*: 2020-02-24
    Sponsor Name:Universtitätsklinikum St.Pölten
    Full Title: A prospective, randomized, multicenter trial to compare a Taurolock™ based lock solution to a Citrate and Citrate/Urokinase based lock solution in tunneled hemodialysis catheters for the prevention...
    Medical condition: Patients requiring hemodialysis with a CVC due to renal failure of any cause. Aim of this study is to investigate different CVC lock Solutions.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-005116-64 Sponsor Protocol Number: 16092021 Start Date*: 2021-12-13
    Sponsor Name:Aarhus University Hospital, Department of Anesthesiology
    Full Title: Low-dose ketamine as an adjunct to morphine for acute pain in the ED: a randomized, double-blinded, superiority trial
    Medical condition: Acute pain in the Emergency Department
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004867 10066714 Acute pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-005768-74 Sponsor Protocol Number: ImmunoSep Start Date*: 2021-02-18
    Sponsor Name:Hellenic Institute for the Study of Sepsis
    Full Title: PERSONALIZED IMMUNOTHERAPY IN SEPSIS: A MULTICENTRE AND MULTINATIONAL, DOUBLE-BLIND, DOUBLE-DUMMY RANDOMIZED CLINICAL TRIAL (THE IMMUNOSEP TRIAL)
    Medical condition: Sepsis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10040053 Sepsis secondary LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed) NL (Completed) DE (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-000201-84 Sponsor Protocol Number: AT2020_01 Start Date*: 2020-04-07
    Sponsor Name:Das Kinderwunsch Institut Schenk GmbH
    Full Title: Oral and intravenous iron substitution for the treatment of iron deficiency symptoms in the context of fertility treatment - an exploratory pilot study
    Medical condition: infertility
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-000220-19 Sponsor Protocol Number: 2.2 Start Date*: 2020-09-24
    Sponsor Name:Verein zur Förderung von Wissenschaft und Forschung an der 1. Med. Abteilung der Krankenanstalt Rudolfstiftung
    Full Title: Comparing effects of weight loss by Liraglutide 3.0 mg with conventional liver fasting in non-alcoholic fatty liver disease before bariatric surgery
    Medical condition: Obesity and NAFLD can increase the risk and complexity of bariatric surgery up to 20%. Reducing the weight and liver size before bariatric surgery improves the operation area and reduces complicati...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-004489-16 Sponsor Protocol Number: V3_KET_NEG_SYMPT_SCZ Start Date*: 2021-11-03
    Sponsor Name:Medizinische Universität Wien, Universitätsklinik für Psychiatrie und Psychotherapie
    Full Title: Ketamine for the treatment of depressive and negative symptoms in patients with schizophrenia: a randomized controlled cross-over pilot study.
    Medical condition: Negative and depressive symptoms of schizophrenia according to DSM-5
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2020-003092-18 Sponsor Protocol Number: TIKTAC Start Date*: 2021-05-12
    Sponsor Name:Medical University Innsbruck
    Full Title: Daratumumab in combination with Carfilzomib, Pomalidomide and Dexamethasone (DCPD) in patients with multiple myeloma induced acute renal failure - “Time Is Kidney in the Treatment of myelomA Cast n...
    Medical condition: Multiple Myeloma: cohort 1: dialysis dependent patients; cohort 2: patients not dialysis dependent
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-005726-29 Sponsor Protocol Number: CariCog Start Date*: 2021-02-23
    Sponsor Name:Medical University Innsbruck
    Full Title: An open label signal detection study to evaluate the effects of cariprazine on cognitive functioning in patients with schizophrenia in need of adjustment of oral antipsychotic treatment
    Medical condition: Schizophrenia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2019-004501-27 Sponsor Protocol Number: 2183/2019 Start Date*: 2021-01-28
    Sponsor Name:Medical University of Vienna
    Full Title: Perioperative analgesia in children undergoing ophthalmic surgery
    Medical condition: perioperative analgesia
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-002752-20 Sponsor Protocol Number: LAN_POAF_01 Start Date*: 2020-12-17
    Sponsor Name:Medical University of Vienna
    Full Title: A prospective, randomized, double- blind, placebo- controlled study to evaluate the efficacy of Landiolol hydrochloride for prevention of atrial fibrillation in patients undergoing cardiac surgery
    Medical condition: Perioperative atrial fibrillation (POAF) is the most common arryhthmia after cardiac surgery with incidences ranging from 20% to 40%, depending on various patient's risk factors and the type of sur...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2020-003255-15 Sponsor Protocol Number: Benzylbenzoat-Ivermectin-5020 Start Date*: 2020-12-17
    Sponsor Name:Landeskrankenhaus Salzburg
    Full Title: Investigation to assess the efficacy of benzyl benzoate 10/25% emulsion versus oral ivermectin for scabies treatment
    Medical condition: Scabies
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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