- Trials with a EudraCT protocol (5,339)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (2,040)
5,339 result(s) found for: Neoplasms.
Displaying page 46 of 267.
EudraCT Number: 2009-012007-25 | Sponsor Protocol Number: BAY43-9006/14295 | Start Date*: 2009-10-21 | |||||||||||||||||||||
Sponsor Name:Bayer AG | |||||||||||||||||||||||
Full Title: A Double-Blind, Randomized Phase III Study Evaluating the Efficacy and Safety of Sorafenib Compared to Placebo in Locally Advanced/Metastatic RAI-Refractory Differentiated Thyroid Cancer | |||||||||||||||||||||||
Medical condition: Differentiated thyroid cancer | |||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
Trial protocol: DE (Completed) GB (Completed) ES (Completed) IT (Completed) NL (Completed) FR (Completed) DK (Completed) SE (Completed) BE (Completed) AT (Completed) SK (Completed) BG (Completed) | |||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2016-003315-35 | Sponsor Protocol Number: B7461006 | Start Date*: 2017-08-01 | |||||||||||||||||||||
Sponsor Name:Pfizer Inc, | |||||||||||||||||||||||
Full Title: A Phase 3, randomized, open-label study of lorlatinib (PF-06463922) monotherapy versus crizotinib monotherapy in the first-line treatment of patients with advanced ALK-positive non-small cell lung ... | |||||||||||||||||||||||
Medical condition: Advanced ALK positive non small cell lung cancer | |||||||||||||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||||||||||||
Trial protocol: DE (Trial now transitioned) DK (Prematurely Ended) CZ (Trial now transitioned) BE (Trial now transitioned) NL (Trial now transitioned) PL (Trial now transitioned) ES (Ongoing) FR (Trial now transitioned) IT (Trial now transitioned) | |||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2018-001585-42 | Sponsor Protocol Number: CA209-8KX | Start Date*: 2019-01-09 | ||||||||||||||||||||||||||||||||||||
Sponsor Name:Bristol-Myers Squibb International Corporation | ||||||||||||||||||||||||||||||||||||||
Full Title: Phase I/II pharmacokinetic multi-tumor study of subcutaneous formulation of nivolumab monotherapy | ||||||||||||||||||||||||||||||||||||||
Medical condition: The study population will include participants with 1 of the following advanced or metastatic tumors approved for treatment with nivolumab monotherapy: non-small cell lung cancer (NSCLC); renal ce... | ||||||||||||||||||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||||||||||||
Trial protocol: PL (Ongoing) GB (GB - no longer in EU/EEA) ES (Ongoing) NL (Trial now transitioned) IT (Trial now transitioned) | ||||||||||||||||||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2021-005201-27 | Sponsor Protocol Number: D361EC00001 | Start Date*: 2022-06-27 | |||||||||||||||||||||
Sponsor Name:AstraZeneca AB | |||||||||||||||||||||||
Full Title: A Phase III Double-Blind, Randomised, Placebo-Controlled Study Assessing the Efficacy and Safety of Capivasertib + Docetaxel Versus Placebo + Docetaxel as Treatment for Patients with Metastatic Cas... | |||||||||||||||||||||||
Medical condition: Metastatic Castration Resistant Prostate Cancer | |||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male | ||||||||||||||||||||||
Trial protocol: ES (Ongoing) GR (Trial now transitioned) BE (Trial now transitioned) PL (Trial now transitioned) CZ (Trial now transitioned) NL (Trial now transitioned) FR (Trial now transitioned) | |||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2015-000662-65 | Sponsor Protocol Number: D5164C00001 | Start Date*: 2015-08-12 | |||||||||||||||||||||
Sponsor Name:AstraZeneca AB | |||||||||||||||||||||||
Full Title: A Phase III, double-blind, randomized, placebo-controlled multi-centre, study to assess the efficacy and safety of AZD9291 versus Placebo, in patients with Epidermal Growth Factor Receptor Mutation... | |||||||||||||||||||||||
Medical condition: Stage IB-IIIA non-small cell lung carcinoma, with a centrally confirmed, common sensitising EGFR mutations (Ex19del and L858R either alone or in combination with other EGFR mutations), following co... | |||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
Trial protocol: BE (Trial now transitioned) IT (Completed) DE (Trial now transitioned) HU (Completed) NL (Ongoing) FR (Trial now transitioned) ES (Ongoing) PL (Trial now transitioned) SE (Trial now transitioned) | |||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2017-000202-37 | Sponsor Protocol Number: AGOOVAR229 | Start Date*: 2018-05-04 | |||||||||||||||||||||
Sponsor Name:AGO Research GmbH | |||||||||||||||||||||||
Full Title: Atezolizumab in combination with Bevacizumab and Chemotherapy versus Bevacizumab and Chemotherapy in recurrent ovarian cancer – a randomized Phase III trial | |||||||||||||||||||||||
Medical condition: Efficacy of atezolizumab in combination with non-platinum based chemotherapy and bevacizumab versus the combination of a non-platinum based chemotherapy and bevacizumab in recurrent ovarian cancer | |||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Female | ||||||||||||||||||||||
Trial protocol: DE (Completed) AT (Completed) BE (Completed) ES (Ongoing) NO (Completed) DK (Completed) FI (Completed) LT (Prohibited by CA) EE (Completed) | |||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2020-002818-41 | Sponsor Protocol Number: MO42319 | Start Date*: 2021-01-27 | |||||||||||||||||||||
Sponsor Name:F. Hoffmann-La Roche Ltd | |||||||||||||||||||||||
Full Title: A RANDOMIZED, MULTICENTER, DOUBLEBLIND, PLACEBO-CONTROLLED PHASE III STUDY OF THE EFFICACY AND SAFETY OF TRASTUZUMAB EMTANSINE IN COMBINATION WITH ATEZOLIZUMAB OR PLACEBO IN PATIENTS WITH HER2-POSI... | |||||||||||||||||||||||
Medical condition: Locally advanced / metastatic breast cancer | |||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
Trial protocol: SI (Completed) DE (Completed) PT (Completed) NO (Prematurely Ended) HU (Prematurely Ended) FI (Prematurely Ended) PL (Prematurely Ended) FR (Prematurely Ended) IT (Prematurely Ended) | |||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2016-003163-20 | Sponsor Protocol Number: CO-338-063 | Start Date*: 2017-04-28 | ||||||||||||||||
Sponsor Name:Clovis Oncology, Inc. | ||||||||||||||||||
Full Title: TRITON3: A Multicenter, Randomized, Open-label Phase 3 Study of Rucaparib versus Physician’s Choice of Therapy for Patients with Metastatic Castration-resistant Prostate Cancer Associated with Homo... | ||||||||||||||||||
Medical condition: Metastatic castration-resistant prostate cancer | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male | |||||||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) IE (Completed) BE (Completed) ES (Ongoing) DK (Completed) DE (Completed) IT (Completed) | ||||||||||||||||||
Trial results: View results |
EudraCT Number: 2012-005546-38 | Sponsor Protocol Number: AEZS-108-050 | Start Date*: 2013-10-14 | ||||||||||||||||
Sponsor Name:Aeterna Zentaris GmbH | ||||||||||||||||||
Full Title: Randomised controlled study comparing AEZS-108 with doxorubicin as second line therapy for locally advanced, recurrent or metastatic endometrial cancer | ||||||||||||||||||
Medical condition: Endometrial cancer, advanced, recurrent or metastatic | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Female | |||||||||||||||||
Trial protocol: CZ (Completed) BE (Completed) GB (Completed) AT (Completed) DE (Completed) ES (Completed) IE (Completed) IT (Completed) BG (Completed) NL (Completed) PL (Completed) DK (Completed) FI (Completed) | ||||||||||||||||||
Trial results: View results |
EudraCT Number: 2009-017396-19 | Sponsor Protocol Number: CA184104 | Start Date*: 2011-04-12 | ||||||||||||||||
Sponsor Name:Bristol-Myers Squibb International Corporation | ||||||||||||||||||
Full Title: Randomized, Multicenter, Double-Blind, Phase 3 Trial Comparing the Efficacy of Ipilimumab in Addition to Paclitaxel and Carboplatin versus Placebo in Addition to Paclitaxel and Carboplatin in Subje... | ||||||||||||||||||
Medical condition: Stage IV/Recurrent Non-Small Cell Lung Cancer | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: HU (Completed) SE (Completed) DE (Completed) BE (Completed) GB (Completed) AT (Completed) NL (Completed) DK (Completed) CZ (Completed) PT (Completed) IE (Completed) ES (Completed) IT (Completed) | ||||||||||||||||||
Trial results: View results |
EudraCT Number: 2016-004672-21 | Sponsor Protocol Number: CR-AIR-009 | Start Date*: 2017-06-15 | |||||||||||||||||||||||||||||||
Sponsor Name:Kiadis Pharma Netherlands B.V. | |||||||||||||||||||||||||||||||||
Full Title: A Phase III, multicenter, randomized controlled study to compare safety and efficacy of a haploidentical HSCT and adjunctive treatment with ATIR101, a T-lymphocyte enriched leukocyte preparation de... | |||||||||||||||||||||||||||||||||
Medical condition: Patients with a hematologic malignancy (AML, ALL, or MDS) who are eligible for a haploidentical HSCT | |||||||||||||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||||||||||||
Trial protocol: BE (Completed) GB (GB - no longer in EU/EEA) DE (Prematurely Ended) ES (Completed) PT (Completed) NL (Prematurely Ended) HR (Completed) FR (Prematurely Ended) IT (Prematurely Ended) | |||||||||||||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2017-004692-31 | Sponsor Protocol Number: CA017-078 | Start Date*: 2019-03-18 | ||||||||||||||||
Sponsor Name:Bristol-Myers Squibb International Corporation | ||||||||||||||||||
Full Title: A Phase 3, Randomized, Study of Neoadjuvant Chemotherapy alone versus Neoadjuvant Chemotherapy plus Nivolumab or Nivolumab and BMS-986205, Followed by Continued Post- Surgery Therapy with Nivolumab... | ||||||||||||||||||
Medical condition: Bladder Cancer Muscle-Invasive Bladder Cancer | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: DE (Trial now transitioned) AT (Trial now transitioned) FR (Trial now transitioned) BE (Trial now transitioned) NO (Trial now transitioned) NL (Trial now transitioned) FI (Trial now transitioned) GR (Trial now transitioned) ES (Ongoing) PT (Completed) IT (Trial now transitioned) RO (Trial now transitioned) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2020-004129-22 | Sponsor Protocol Number: CJDQ443A12101 | Start Date*: 2021-02-22 |
Sponsor Name:Novartis Pharma AG | ||
Full Title: A phase Ib/II open-label, multi-center dose escalation study of JDQ443 in patients with advanced solid tumors harboring the KRAS G12C mutation | ||
Medical condition: advanced solid tumors harboring the KRAS G12C mutation | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: FR (Trial now transitioned) BE (Trial now transitioned) DK (Trial now transitioned) DE (Trial now transitioned) NL (Trial now transitioned) IT (Trial now transitioned) | ||
Trial results: (No results available) |
EudraCT Number: 2016-004857-33 | Sponsor Protocol Number: 0416-ASG | Start Date*: 2017-06-01 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sponsor Name:AIO-Studien-gGmbH | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Full Title: A phase II single arm clinical trial of a Tailored ImmunoTherapy Approach with Nivolumab in subjects with metastatic or advanced Transitional Cell Carcinoma | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Medical condition: subjects in untreated (1st line)* and platinum-based pretreated (2nd and 3rd line) subjects with metastatic or surgically unresectable TCC *First-line has been finally stopped since 06.01.2020 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Trial protocol: DE (Completed) AT (Completed) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2013-004076-34 | Sponsor Protocol Number: 7487-CL-0209 | Start Date*: 2014-02-27 | ||||||||||||||||||||||||||
Sponsor Name:Astellas Pharma Global Development, Inc. | ||||||||||||||||||||||||||||
Full Title: A phase II open-label rollover study for subjects that have participated in an Astellas sponsored linsitinib trial | ||||||||||||||||||||||||||||
Medical condition: Solid tumors | ||||||||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||
Trial protocol: CZ (Completed) PL (Completed) GB (Completed) | ||||||||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2006-005476-40 | Sponsor Protocol Number: A5961166 | Start Date*: 2007-02-20 | |||||||||||
Sponsor Name:Pfizer Inc | |||||||||||||
Full Title: PHASE 2 SINGLE-ARM, OPEN LABEL STUDY OF IRINOTECAN IN COMBINATION WITH TEMOZOLOMIDE IN CHILDREN WITH RECURRENT OR REFRACTORY MEDULLOBLASTOMA AND IN CHILDREN WITH NEWLY DIAGNOSED HIGH-GRADE GLIOMA | |||||||||||||
Medical condition: children with recurrent or refractory medulloblastoma and newly diagnosed high-grade glioma | |||||||||||||
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Population Age: Infants and toddlers, Children, Adolescents, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) FR (Completed) DK (Completed) IT (Prematurely Ended) PL (Completed) ES (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2021-003602-41 | Sponsor Protocol Number: 2020-012-GLOB2 | Start Date*: 2022-11-15 |
Sponsor Name:HUTCHMED Limited | ||
Full Title: AN OPEN-LABEL, MULTICENTER PHASE 1/2 STUDY OF SURUFATINIB IN COMBINATION WITH GEMCITABINE IN PEDIATRIC, ADOLESCENT, AND YOUNG ADULT PATIENTS WITH RECURRENT OR REFRACTORY SOLID TUMORS | ||
Medical condition: recurrent or refractory solid tumors or lymphoma (not central nervous system) who have a known or expected dysfunction of vascular endothelial growth factor receptor-1, -2, and -3; fibroblast growt... | ||
Disease: | ||
Population Age: Infants and toddlers, Children, Adolescents, Under 18 | Gender: Male, Female | |
Trial protocol: IT (Prematurely Ended) DE (Prematurely Ended) ES (Ongoing) DK (Prematurely Ended) | ||
Trial results: View results |
EudraCT Number: 2020-004535-24 | Sponsor Protocol Number: RLY-4008-101 | Start Date*: 2021-07-07 | ||||||||||||||||||||||||||||||||||||
Sponsor Name:Relay Therapeutics, Inc. | ||||||||||||||||||||||||||||||||||||||
Full Title: A First-in-Human Study of Highly Selective FGFR2 inhibitor, RLY-4008, in Patients with Intrahepatic Cholangiocarcinoma (ICC) and other Advanced Solid Tumors | ||||||||||||||||||||||||||||||||||||||
Medical condition: Unresectable or metastatic cholangiocarcinoma (CCA), other advanced solid tumors with an FGFR2-alteration or other potential FGFR2-dependent tumors | ||||||||||||||||||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||||||||||||
Trial protocol: SE (Trial now transitioned) NL (Trial now transitioned) DE (Trial now transitioned) | ||||||||||||||||||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2014-003171-39 | Sponsor Protocol Number: T-Control | Start Date*: 2016-03-08 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sponsor Name:University Hospital Wuerzburg | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Full Title: Transfer of Streptamer-selected multi-antigen specific T cells to prevent infections and relapse and to reduce the risk of Graft-versus-Host Disease after allogeneic stem cell transplantation | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Medical condition: patients with hematological malignancies after T cell depleted allo-SCT | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Trial protocol: DE (Completed) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2014-004430-26 | Sponsor Protocol Number: 010207QM | Start Date*: 2015-06-08 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sponsor Name:Queen Mary University of London | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Full Title: FEASIBILITY of IBIS 3. An International Breast Intervention Study investigating Prevention Of Late Recurrence in ER+ breast cancer survivors following 5 years of adjuvant treatment | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Medical condition: Late recurrence of hormone receptor positive breast cancer | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Female | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Trial protocol: GB (Prematurely Ended) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Trial results: View results |
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