- Trials with a EudraCT protocol (22)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
22 result(s) found for: Hyperammonemia.
Displaying page 1 of 2.
EudraCT Number: 2008-000787-16 | Sponsor Protocol Number: C07-22 | Start Date*: 2008-06-12 | |||||||||||
Sponsor Name:Inserm | |||||||||||||
Full Title: Etude pilote ouverte de l'effet de la fluoxetine chez des patientes agées de 8 à 28 ans atteintes du Syndrôme de Rett Typique | |||||||||||||
Medical condition: Sydrome de Rett typique | |||||||||||||
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Population Age: Children, Adolescents, Under 18, Adults | Gender: Female | ||||||||||||
Trial protocol: FR (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2006-006440-55 | Sponsor Protocol Number: Amino Acid 01/2007 | Start Date*: 2007-08-27 | |||||||||||
Sponsor Name:University Childrin's Hospital | |||||||||||||
Full Title: Effect on metabolic acidosis due to hyperammonemia of high versus low intake of amino acid in VLBW infants. | |||||||||||||
Medical condition: At birth, a VLBW infant is abruptly disconnected from the ideal source of parenteral nutrition - the placenta. If the goal of post-natal nutrition in the VLBW infant is to mimic in utero nutrition.... | |||||||||||||
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Population Age: Preterm newborn infants, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2020-003384-25 | Sponsor Protocol Number: DTX301-CL301 | Start Date*: 2022-12-16 | |||||||||||
Sponsor Name:Ultragenyx Pharmaceutical Inc. | |||||||||||||
Full Title: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study of Adeno-Associated Virus Serotype 8 (AAV8)-Mediated Gene Transfer of Human Ornithine Transcarbamylase (OTC) in Patients with Late-Onset... | |||||||||||||
Medical condition: Late-onset Ornithine transcarbamylase (OTC) deficiency | |||||||||||||
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Population Age: Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
Trial protocol: FR (Not Authorised) ES (Ongoing) DE (Ongoing) PT (Ongoing) IT (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2019-004345-32 | Sponsor Protocol Number: ANAVEX2-73-RS-002 | Start Date*: 2020-05-26 | |||||||||||
Sponsor Name:Anavex Germany GmbH | |||||||||||||
Full Title: A Double-Blind, Randomised, Placebo-Controlled, Safety and Efficacy Study of ANAVEX2-73 in Patients with Rett Syndrome | |||||||||||||
Medical condition: Rett Syndrome | |||||||||||||
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Population Age: Adults, Elderly | Gender: Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2018-003370-27 | Sponsor Protocol Number: GWND18064 | Start Date*: 2019-04-09 | |||||||||||
Sponsor Name:GW Research Ltd | |||||||||||||
Full Title: A randomized, double-blind, placebo-controlled trial to investigate the efficacy and safety of cannabidiol oral solution (GWP42003-P; CBD-OS) in patients with Rett syndrome. | |||||||||||||
Medical condition: Rett syndrome (RTT) [typical or atypical] | |||||||||||||
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Population Age: Children, Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) IT (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2019-001605-24 | Sponsor Protocol Number: GWND19002 | Start Date*: 2020-01-15 | |||||||||||
Sponsor Name:GW Research Ltd | |||||||||||||
Full Title: An open-label extension trial to investigate the long-term safety of cannabidiol oral solution (GWP42003-P, CBD-OS) in patients with Rett Syndrome | |||||||||||||
Medical condition: Rett syndrome (RTT) [typical or atypical] | |||||||||||||
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Population Age: Children, Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) ES (Prematurely Ended) IT (Ongoing) | |||||||||||||
Trial results: View results |
EudraCT Number: 2006-000136-27 | Sponsor Protocol Number: CCD02 | Start Date*: 2008-03-17 | |||||||||||||||||||||
Sponsor Name:Cytonet GmbH & Co KG | |||||||||||||||||||||||
Full Title: Open, Prospective, Uncontrolled, Multicentre Study to Evaluate The Safety and Efficacy of Multiple Applications of Liver Cell Suspension Into The Portal Vein in Children with Urea Cycle Disorders (... | |||||||||||||||||||||||
Medical condition: Neonates and Infants up to 3 months including with prenatally or postnatally confirmed urea cycle disorder with below listed deficiency and children aged > 3 months up to 5 years including with con... | |||||||||||||||||||||||
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Population Age: Newborns, Infants and toddlers, Children, Under 18 | Gender: Male, Female | ||||||||||||||||||||||
Trial protocol: DE (Completed) | |||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2012-002120-33 | Sponsor Protocol Number: HLSCS01-11 | Start Date*: 2013-12-06 | ||||||||||||||||||||||||||
Sponsor Name:AZIENDA SANITARIA OSPEDALIERA O.I.R.M. - S. ANNA | ||||||||||||||||||||||||||||
Full Title: Human Liver Stem Cells (HLSCs) in patients suffering from liver-based inborn metabolic diseases causing life-threatening neonatal onset of hyperammonemic encephalopathy | ||||||||||||||||||||||||||||
Medical condition: neonatal hyperammonemic encephalopathy associated with inborn liver metabolic diseases | ||||||||||||||||||||||||||||
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Population Age: Newborns, Under 18 | Gender: Male, Female | |||||||||||||||||||||||||||
Trial protocol: IT (Completed) | ||||||||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2016-001057-40 | Sponsor Protocol Number: 301OTC01 | Start Date*: 2017-03-14 | |||||||||||
Sponsor Name:Ultragenyx Pharmaceutical, Inc. | |||||||||||||
Full Title: A Phase 1/2, Open-Label Safety and Dose-Finding Study of Adeno-Associated Virus (AAV) Serotype 8 (AAV8)-Mediated Gene Transfer of Human Ornithine Transcarbamylase (OTC) in Adults with Late-Onset OT... | |||||||||||||
Medical condition: Ornithine transcarbamylase deficiency | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) ES (Ongoing) | |||||||||||||
Trial results: View results |
EudraCT Number: 2022-000933-18 | Sponsor Protocol Number: HLSC-UCD-02 | Start Date*: Information not available in EudraCT | |||||||||||
Sponsor Name:Unicyte AG | |||||||||||||
Full Title: An Open-label, Non-controlled, Multi-center, Phase 2 Study to Assess the Efficacy and Safety of Allogeneic Human Liver Stem Cells (HLSCs) in the Treatment of Pediatric Patients with Early-onset Ure... | |||||||||||||
Medical condition: Urea cycle disorders | |||||||||||||
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Population Age: Newborns, Infants and toddlers, Children, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: FR (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2009-012602-39 | Sponsor Protocol Number: 05-NEOV-002 | Start Date*: 2010-05-17 | |||||||||||
Sponsor Name:Fresenius Kabi Deutschland GmbH | |||||||||||||
Full Title: A randomised, double-blind study evaluating the safety, tolerability, protein accretion, amino acid plasma levels and long-term outcome of Neoven compared to Vaminolact(R) in premature very low bir... | |||||||||||||
Medical condition: The product is aimed to be used where parenteral nutrition is required. The intended indication is: Supply of essential and non-essential amino acids as part of parenteral nutrition for premature ... | |||||||||||||
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Population Age: Preterm newborn infants, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Prematurely Ended) NL (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2015-004448-20 | Sponsor Protocol Number: Sarizotan/001/II/2015 | Start Date*: 2016-11-28 | |||||||||||
Sponsor Name:Newron Pharmaceuticals S.p.A. | |||||||||||||
Full Title: A Randomized, Double-Blind, Placebo-Controlled, Six-Month Study to Evaluate the Efficacy, Safety and Tolerability of Sarizotan in Patients with Rett Syndrome with Respiratory Symptoms | |||||||||||||
Medical condition: Rett syndrome | |||||||||||||
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Population Age: Children, Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Prematurely Ended) IT (Ongoing) | |||||||||||||
Trial results: View results |
EudraCT Number: 2009-012604-92 | Sponsor Protocol Number: 05-NEOV-004 | Start Date*: 2010-04-19 | |||||||||||
Sponsor Name:Fresenius Kabi Deutschland GmbH | |||||||||||||
Full Title: A randomised, double-blind study of the safety and efficacy of Neoven compared to Vaminolact in infants and children requiring long-term parenteral nutrition | |||||||||||||
Medical condition: The product is aimed to be used where parenteral nutrition is required. The intended indication is: Supply of essential and non-essential amino acids as part of Parenteral Nutrition for infants an... | |||||||||||||
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Population Age: Infants and toddlers, Children, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: FR (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2018-003163-67 | Sponsor Protocol Number: CAEB1102-102A | Start Date*: 2019-01-15 | |||||||||||
Sponsor Name:Aeglea Biotherapeutics, Inc. | |||||||||||||
Full Title: An Open-label, Multicenter Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of AEB1102 in Patients with Arginase I Deficiency | |||||||||||||
Medical condition: Arginase 1 deficiency Hyperargininemia | |||||||||||||
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Population Age: Children, Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) PT (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2009-012603-26 | Sponsor Protocol Number: 05-NEOV-003 | Start Date*: 2010-04-08 | |||||||||||
Sponsor Name:Fresenius Kabi Deutschland GmbH [...] | |||||||||||||
Full Title: A randomised, double-blind study evaluating the safety, tolerability and clinical outcome of Neoven compared to Vaminolact in premature ELBW infants | |||||||||||||
Medical condition: The product is aimed to be used where parenteral nutrition is required. The intended indication is: Supply of essential and non-essential amino acids as part of Parenteral Nutrition for premature ... | |||||||||||||
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Population Age: Preterm newborn infants, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: BE (Completed) DE (Prematurely Ended) FR (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2021-001081-38 | Sponsor Protocol Number: ARCT-810-03 | Start Date*: 2021-12-23 | |||||||||||
Sponsor Name:Arcturus Therapeutics, Inc. | |||||||||||||
Full Title: Phase 2, Randomized, Double-Blind, Placebo-Controlled, Nested Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of ARCT-810 in Adolescent and Adult ... | |||||||||||||
Medical condition: Ornithine transcarbamylase deficiency | |||||||||||||
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Population Age: Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: BE (Ongoing) ES (Ongoing) SE (Restarted) IT (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2018-000156-18 | Sponsor Protocol Number: 301OTC02 | Start Date*: 2018-08-15 | |||||||||||
Sponsor Name:Ultragenyx Pharmaceutical, Inc. | |||||||||||||
Full Title: A Long-Term Follow-up Study to Evaluate the Safety and Efficacy of Adeno-Associated Virus (AAV) Serotype 8 (AAV8)-Mediated Gene Transfer of Human Ornithine Transcarbamylase (OTC) in Adults with Lat... | |||||||||||||
Medical condition: Ornithine transcarbamylase deficiency | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) ES (Ongoing) FR (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2011-002472-16 | Sponsor Protocol Number: CCD09 | Start Date*: 2011-12-19 | |||||||||||
Sponsor Name:Cytonet GmbH & Co KG | |||||||||||||
Full Title: Open, prospective, diagnostic, multicentre study in healthy subjects, patients with urea cycle disorders (UCD), and carriers of UCD mutations, to evaluate in vivo ureagenesis measured after a singl... | |||||||||||||
Medical condition: 1. Healthy subjects 2. Symptomatic UCD patients with genetically confirmed CPSD, OTCD, ASSD, or ASLD 3. Asymptomatic carriers of UCD mutations (e.g. parents) | |||||||||||||
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Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2013-005412-10 | Sponsor Protocol Number: OCR002-HE209 | Start Date*: 2014-08-25 | |||||||||||
Sponsor Name:Ocera Therapeutics Inc | |||||||||||||
Full Title: Multicenter, Randomized Phase 2B Study to Evaluate the Efficacy, Safety and Tolerability of OCR-002 (ornithine phenylacetate) in Hospitalized Patients with Cirrhosis and Associated Hyperammonemi... | |||||||||||||
Medical condition: Hepatic encephalopathy | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: EE (Completed) CZ (Completed) AT (Completed) HU (Completed) IT (Completed) DE (Completed) NL (Completed) BE (Completed) DK (Completed) BG (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2017-003851-45 | Sponsor Protocol Number: CAEB1102-101A | Start Date*: 2018-03-14 | |||||||||||
Sponsor Name:Aeglea Biotherapeutics, Inc. | |||||||||||||
Full Title: A Phase 1/2 Open-label Study in Patients with Arginase I Deficiency to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of Intravenous AEB1102 | |||||||||||||
Medical condition: Arginase 1 deficiency Hyperargininemia | |||||||||||||
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Population Age: Children, Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) PT (Completed) | |||||||||||||
Trial results: View results |
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