- Trials with a EudraCT protocol (81)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
81 result(s) found for: Epidermal cells.
Displaying page 4 of 5.
| EudraCT Number: 2020-000428-21 | Sponsor Protocol Number: EUROPATRIAL | Start Date*: 2021-01-19 | |||||||||||
| Sponsor Name:DIPARTIMENTO DI SCIENZE BIOMEDICHE SPERIMENTALI E CLINICHE, UNIVERSITà DI FIRENZE | |||||||||||||
| Full Title: ExclUsive endocRine therapy Or Partial breast irradiation for women aged =70 years with luminal A-like early stage breast cancer (EUROPA): a randomized phase 3 non-inferiority trial. | |||||||||||||
| Medical condition: Patients aged >=70 years with T1 N0 breast cancer (dimensions <2 cm and negative axillary lymph nodes) with luminal A-like characteristics (ER >=10% PgR >20% HER2 negative Ki67 <20%), after conserv... | |||||||||||||
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| Population Age: Elderly | Gender: Female | ||||||||||||
| Trial protocol: IT (Trial now transitioned) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2018-001438-16 | Sponsor Protocol Number: OBI-822-011 | Start Date*: 2022-01-25 | |||||||||||
| Sponsor Name:OBI Pharma, Inc. | |||||||||||||
| Full Title: The GLORIA Study: A Phase 3, Randomized, Open-Label Study of the Anti-Globo H Vaccine Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients with High-Risk, Early-Stage Globo H... | |||||||||||||
| Medical condition: Triple Negative Breast Cancer | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: PL (Trial now transitioned) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2014-002161-30 | Sponsor Protocol Number: 1302.5 | Start Date*: 2015-09-07 | |||||||||||||||||||||
| Sponsor Name:Boehringer Ingelheim International GmbH | |||||||||||||||||||||||
| Full Title: A multicenter, randomized, double-blind Phase III trial to evaluate efficacy and safety of BI 695502 plus chemotherapy versus Avastin® plus chemotherapy in patients with advanced nonsquamous Non-Sm... | |||||||||||||||||||||||
| Medical condition: Recurrent or metastatic disease (Stage IV), histologically or cytologically confirmed advanced nonsquamous Non-Small Cell Lung Cancer. | |||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
| Trial protocol: HU (Completed) PT (Completed) ES (Completed) DE (Completed) PL (Completed) HR (Completed) GR (Completed) | |||||||||||||||||||||||
| Trial results: View results | |||||||||||||||||||||||
| EudraCT Number: 2021-004061-13 | Sponsor Protocol Number: ESR21-21165 | Start Date*: 2022-06-09 | ||||||||||||||||
| Sponsor Name:VHIO Vall d’Hebron Institute of Oncology | ||||||||||||||||||
| Full Title: Single cell characterization of persistent cells upon treatment with durvalumab (MEDI4736) with or without tremelimumab in MSS and MSI colorectal and endometrial tumors | ||||||||||||||||||
| Medical condition: MSS and MSI colorectal and endometrial tumors | ||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
| Trial protocol: ES (Ongoing) | ||||||||||||||||||
| Trial results: (No results available) | ||||||||||||||||||
| EudraCT Number: 2021-005110-34 | Sponsor Protocol Number: ICT01-102 | Start Date*: 2022-02-08 | ||||||||||||||||||||||||||
| Sponsor Name:ImCheck Therapeutics, Inc. | ||||||||||||||||||||||||||||
| Full Title: A two-part, open-label, clinical study to assess the safety, tolerability and activity of intravenous doses of ICT01 in combination with low-dose subcutaneous interleukin-2 in patients with advance... | ||||||||||||||||||||||||||||
| Medical condition: Relapsed/refractory patients with advanced solid tumors : metastatic colorectal cancer (CRC) or metastatic ovarian cancer or metastatic castration-resistant prostate cancer (mCRPC) or metastatic pa... | ||||||||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||
| Trial protocol: FR (Trial now transitioned) DE (Trial now transitioned) | ||||||||||||||||||||||||||||
| Trial results: (No results available) | ||||||||||||||||||||||||||||
| EudraCT Number: 2016-003924-22 | Sponsor Protocol Number: ML39349 | Start Date*: 2017-05-03 | ||||||||||||||||
| Sponsor Name:ROCHE SAS | ||||||||||||||||||
| Full Title: AN OPEN-LABEL, MULTICENTER, SINGLE-ARM, PHASE II STUDY TO ASSESS THE EFFICACY AND SAFETY OF ALECTINIB IN PATIENTS WITH ALK-REARRANGED NON−SMALL CELL LUNG CANCER AFTER DISEASE PROGRESSION ON PRIOR A... | ||||||||||||||||||
| Medical condition: ALK-rearranged non-small cell lung cancer (NSCLC) after disease progression on prior ALK inhibitor therapy | ||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
| Trial protocol: FR (Completed) | ||||||||||||||||||
| Trial results: View results | ||||||||||||||||||
| EudraCT Number: 2021-003402-46 | Sponsor Protocol Number: CAN04CLIN005 | Start Date*: 2021-09-23 | |||||||||||
| Sponsor Name:Cantargia AB | |||||||||||||
| Full Title: A randomized non-comparative open-label phase 1b/2 study of nadunolimab in combination with gemcitabine plus carboplatin in patients with advanced triple negative breast cancer. “TRIFOUR study”. | |||||||||||||
| Medical condition: Unresectable locally advanced or metastatic triple negative breast cancer. | |||||||||||||
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| Population Age: Adults | Gender: Male, Female | ||||||||||||
| Trial protocol: ES (Ongoing) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2011-003571-11 | Sponsor Protocol Number: IFCT-1003 | Start Date*: 2018-11-30 | |||||||||||||||||||||
| Sponsor Name:IFCT | |||||||||||||||||||||||
| Full Title: A randomised, phase II trial to evaluate a treatment with Tyrosine Kinase Inhibitor of Epidermal Growth Factor (EGFR-TKI) versus EGFR-TKI associated with an anti-estrogen treatment (fulvestrant) in... | |||||||||||||||||||||||
| Medical condition: advanced stage non squamous non small cell lung cancer | |||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Female | ||||||||||||||||||||||
| Trial protocol: FR (Completed) | |||||||||||||||||||||||
| Trial results: View results | |||||||||||||||||||||||
| EudraCT Number: 2016-002017-22 | Sponsor Protocol Number: 63723283LUC1001 | Start Date*: 2016-11-16 | |||||||||||
| Sponsor Name:Janssen-Cilag International NV | |||||||||||||
| Full Title: A First-in-Human, Open-label, Phase 1/2 Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of JNJ-63723283, an Anti-PD-1 Monoclonal Antibody, in Subjects with A... | |||||||||||||
| Medical condition: Advanced Stage Solid Tumors | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: ES (Ongoing) PL (Trial now transitioned) GB (GB - no longer in EU/EEA) IT (Completed) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2018-001456-34 | Sponsor Protocol Number: CTMX-M-2029-001 | Start Date*: 2019-01-17 | |||||||||||||||||||||||||||||||
| Sponsor Name:CytomX Therapeutics, Inc. | |||||||||||||||||||||||||||||||||
| Full Title: A Phase 1-2, First-in-Human Study of CX-2029 in Adults with Metastatic or Locally Advanced Unresectable Solid Tumors or Diffuse Large B-cell Lymphomas | |||||||||||||||||||||||||||||||||
| Medical condition: Metastatic or locally advanced unresectable solid tumor or diffuse large B-cell lymphoma | |||||||||||||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||||||||||||
| Trial protocol: ES (Ongoing) GB (GB - no longer in EU/EEA) | |||||||||||||||||||||||||||||||||
| Trial results: (No results available) | |||||||||||||||||||||||||||||||||
| EudraCT Number: 2013-003252-20 | Sponsor Protocol Number: 989 | Start Date*: 2014-03-25 | ||||||||||||||||
| Sponsor Name:Biotest AG | ||||||||||||||||||
| Full Title: An open-label, two-stage Phase I/IIa dose escalation study of BT062 in metastatic triple receptor-negative breast cancer and in metastatic transitional cell carcinoma of the urinary bladder | ||||||||||||||||||
| Medical condition: Subjects with metastatic triple receptor-negative breast cancer (TNBC) who failed at least 2 and no more than 4 prior chemotherapies or alternatively Subjects with metastatic transitional cell c... | ||||||||||||||||||
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| Population Age: Elderly | Gender: Male, Female | |||||||||||||||||
| Trial protocol: DE (Completed) BE (Completed) | ||||||||||||||||||
| Trial results: View results | ||||||||||||||||||
| EudraCT Number: 2015-003892-31 | Sponsor Protocol Number: MedOPP089 | Start Date*: 2017-03-23 | |||||||||||
| Sponsor Name:Medica Scientia Innovation Research (MedSIR) | |||||||||||||
| Full Title: A multicenter, international, non-controlled, phase II trial to identify the molecular mechanisms of resistance and sensitivity to palbociclib re-challenge upon progression to a palbociclib combina... | |||||||||||||
| Medical condition: Patients with hormone receptor (HR)-positive/HER2-negative locally advanced or metastatic breast cancer (mBC). Second/third-line of endocrine treatment. | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Female | ||||||||||||
| Trial protocol: ES (Completed) IT (Completed) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2017-004651-23 | Sponsor Protocol Number: IJB-SYNERGY-012017 | Start Date*: 2018-10-16 | |||||||||||||||||||||
| Sponsor Name:Institut Jules Bordet | |||||||||||||||||||||||
| Full Title: A Phase I/II Study of Paclitaxel plus Carboplatin and Durvalumab (MEDI4736) with or without Oleclumab (MEDI9447) for Previously Untreated Locally Recurrent Inoperable or Metastatic Triple-negative ... | |||||||||||||||||||||||
| Medical condition: Previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer (TNBC) | |||||||||||||||||||||||
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| Population Age: Adults | Gender: Male, Female | ||||||||||||||||||||||
| Trial protocol: BE (Trial now transitioned) FR (Trial now transitioned) | |||||||||||||||||||||||
| Trial results: (No results available) | |||||||||||||||||||||||
| EudraCT Number: 2018-001881-40 | Sponsor Protocol Number: BO40747 | Start Date*: 2018-11-27 | |||||||||||
| Sponsor Name:F. Hoffmann-La Roche Ltd | |||||||||||||
| Full Title: A phase III, randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of Atezolizumab or placebo in combination with neoadjuvant doxorubicin + cyclophosphamid... | |||||||||||||
| Medical condition: Early Human epidermal growth factor receptor 2 (HER2)-positive breast cancer | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: DE (Completed) CZ (Completed) ES (Temporarily Halted) PL (Completed) IT (Completed) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2015-001377-40 | Sponsor Protocol Number: MO29694 | Start Date*: 2016-09-22 | |||||||||||||||||||||
| Sponsor Name:Roche Farma, S.A. que representa en España a F. Hoffmann-La Roche Ltd | |||||||||||||||||||||||
| Full Title: PHASE II, EXPLORATORY, MULTICENTER, NON RANDOMIZED, SINGLE AGENT COHORT STUDY TO DETERMINE BEST TUMOR RESPONSE WITH TRASTUZUMAB EMTANSINE IN HER2 OVEREXPRESSING SOLID TUMORS. | |||||||||||||||||||||||
| Medical condition: Human epidermal growth factor receptor 2 (HER2) overexpressing solid tumors specifically metastatic urothelial bladder cancer (MUBC) as well as pancreas/cholangio cancer, which are locally advanced... | |||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
| Trial protocol: ES (Completed) SK (Completed) NL (Completed) IT (Completed) | |||||||||||||||||||||||
| Trial results: View results | |||||||||||||||||||||||
| EudraCT Number: 2022-001087-10 | Sponsor Protocol Number: ELA-0121 | Start Date*: 2022-11-21 | |||||||||||
| Sponsor Name:Stemline Therapeutics, Inc | |||||||||||||
| Full Title: An Open-label Multicenter Phase 1b-2 Study of Elacestrant as Monotherapy and in Combination with Abemaciclib in Women and Men with Brain Metastasis from Estrogen Receptor Positive, HER-2 Negative B... | |||||||||||||
| Medical condition: Brain Metastasis from Estrogen Receptor Positive, HER-2 Negative Breast Cancer | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: ES (Ongoing) IT (Trial now transitioned) BE (Trial now transitioned) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2017-002567-17 | Sponsor Protocol Number: 8951-CL-0301 | Start Date*: 2018-07-13 | |||||||||||
| Sponsor Name:Astellas Pharma Global Development, Inc. (APGD) | |||||||||||||
| Full Title: A Phase 3, Global, Multi-Center, Double-Blind, Randomized, Efficacy Study of IMAB362 Plus mFOLFOX6 Compared with Placebo Plus mFOLFOX6 as First-line Treatment of Subjects with Claudin (CLDN)18.2-Po... | |||||||||||||
| Medical condition: Claudin (CLDN)18.2-Positive, HER2-Negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: FR (Trial now transitioned) GB (GB - no longer in EU/EEA) DE (Trial now transitioned) BE (Trial now transitioned) ES (Ongoing) PL (Trial now transitioned) IT (Trial now transitioned) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2021-003369-37 | Sponsor Protocol Number: D9077C00001 | Start Date*: 2022-04-14 | |||||||||||||||||||||
| Sponsor Name:AstraZeneca AB | |||||||||||||||||||||||
| Full Title: A Phase II Open-label, Multicentre, Randomised Study of Neoadjuvant and Adjuvant Treatment in Patients with Resectable, Early-stage (II to IIIA) Non-small Cell Lung Cancer (NeoCOAST-2) | |||||||||||||||||||||||
| Medical condition: Resectable, Early-stage (II to IIIA) Non-small Cell Lung Cancer | |||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
| Trial protocol: FR (Trial now transitioned) ES (Ongoing) IT (Trial now transitioned) PT (Trial now transitioned) BE (Trial now transitioned) | |||||||||||||||||||||||
| Trial results: (No results available) | |||||||||||||||||||||||
| EudraCT Number: 2018-003739-32 | Sponsor Protocol Number: 1801 | Start Date*: 2020-02-28 | ||||||||||||||||
| Sponsor Name:Actuate Therapeutics Inc | ||||||||||||||||||
| Full Title: Actuate 1801: Phase 1/2 Study of 9-ING-41, a Glycogen Synthase Kinase-3 Beta (GSK-3β) Inhibitor, as a Single Agent and Combined with Chemotherapy, in Patients with Refractory Hematological Malignan... | ||||||||||||||||||
| Medical condition: Refractory Hematologic Malignancies or Solid Tumors | ||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
| Trial protocol: NL (Completed) PT (Trial now transitioned) | ||||||||||||||||||
| Trial results: (No results available) | ||||||||||||||||||
| EudraCT Number: 2022-000199-20 | Sponsor Protocol Number: ML43171 | Start Date*: 2022-07-27 | ||||||||||||||||||||||||||
| Sponsor Name:Genentech, Inc. | ||||||||||||||||||||||||||||
| Full Title: A PHASE III RANDOMIZED, OPEN-LABEL, MULTICENTER STUDY EVALUATING THE EFFICACY AND SAFETY OF GIREDESTRANT PLUS EVEROLIMUS COMPARED WITH EXEMESTANE PLUS EVEROLIMUS IN PATIENTS WITH ESTROGEN RECEPTOR-... | ||||||||||||||||||||||||||||
| Medical condition: Estrogen Receptor (ER)-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer previously treated with a CDK4/6 inhibitor and endocrine therapy | ||||||||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||
| Trial protocol: ES (Ongoing) IT (Trial now transitioned) GR (Trial now transitioned) | ||||||||||||||||||||||||||||
| Trial results: (No results available) | ||||||||||||||||||||||||||||
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