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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 1,889 of 2,219.
    EudraCT Number: 2016-000297-38 Sponsor Protocol Number: CL1-68587-003 Start Date*: 2016-06-22
    Sponsor Name:Institut de Recherches Internationales Servier (I.R.I.S)
    Full Title: Long-term follow-up study of patients who have previously been exposed to UCART19 / ALLO-501 (allogeneic engineered T-cells expressing a lentiviral-based anti-CD19 chimeric antigen receptor)
    Medical condition: Advanced lymphoid malignancies
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10060390 Leukaemia lymphoblastic acute LLT
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10008958 Chronic lymphocytic leukaemia PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) FR (Ongoing) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-004739-22 Sponsor Protocol Number: DER-201805 Start Date*: 2021-03-16
    Sponsor Name:Rheinische Friedrich-Wilhelms-Universität Bonn
    Full Title: Efficacy of ruxolitinib cream in Prurigo nodularis patients: A randomized, placebo-controlled pilot study (PRUX)
    Medical condition: Patients with symptomatic Prurigo nodularis with active skin manifestations
    Disease: Version SOC Term Classification Code Term Level
    20.0 10040785 - Skin and subcutaneous tissue disorders 10037084 Prurigo nodularis LLT
    20.0 10040785 - Skin and subcutaneous tissue disorders 10037083 Prurigo PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-001389-12 Sponsor Protocol Number: PICS1.0 Start Date*: 2020-10-29
    Sponsor Name:Aarhus University Hospital
    Full Title: The Postoperative Iron in Cardiac Surgery (PICS-) trial: A randomised clinical trial comparing the efficacy of single-, high-dose intravenous iron and oral iron for the treatment of anaemia followi...
    Medical condition: Anaemia following cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    22.0 100000004851 10057220 Acute post haemorrhagic anaemia LLT
    20.0 100000004851 10022974 Iron deficiency anemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2020-002489-15 Sponsor Protocol Number: 380119 Start Date*: 2021-03-23
    Sponsor Name:Medinova AG
    Full Title: Comparative study of the efficacy and safety of vaginally applied Dequalinium Chloride (10 mg) and orally applied Metronidazole (2 x 500 mg) in the treatment of bacterial vaginosis
    Medical condition: Bacterial vaginosis
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10004055 Bacterial vaginosis PT
    Population Age: Adults Gender: Female
    Trial protocol: CZ (Prematurely Ended) SK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-001988-24 Sponsor Protocol Number: M602011069 Start Date*: 2021-09-07
    Sponsor Name:Merz Pharmaceuticals GmbH
    Full Title: Prospective, randomized, double-blind, placebo-controlled, parallel-group trial with an open-label period to investigate the efficacy and safety of NT201 in the unilateral and bilateral treatment o...
    Medical condition: Essential tremor [ET] of the upper limb [UL]
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029205 - Nervous system disorders 10015496 Essential tremor PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: View results
    EudraCT Number: 2022-000714-33 Sponsor Protocol Number: PT26/17/01 Start Date*: 2023-02-21
    Sponsor Name:tiakis Biotech AG (formerly Proteo Biotech AG)
    Full Title: Efficacy and safety of Tiprelestat for treatment of severe COVID-19 (COMCOVID trial)
    Medical condition: Adult patients with COVID-19 fulfilling the following criteria: -First laboratory-confirmation of the current episode of SARS-CoV-2 infection (COVID-19) as determined by PCR or antigen test (no sel...
    Disease: Version SOC Term Classification Code Term Level
    23.1 100000004862 10084401 COVID-19 respiratory infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2019-001587-30 Sponsor Protocol Number: 012657 Start Date*: 2019-07-26
    Sponsor Name:Queen Mary University London
    Full Title: AZD1656 in Transplantation with Diabetes tO PromoTe Immune TOleraNce
    Medical condition: renal transplant AND type 2 diabetes
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10023438 Kidney transplant LLT
    20.0 10027433 - Metabolism and nutrition disorders 10012601 Diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2005-005874-65 Sponsor Protocol Number: ISS-UZA-5/26/99 Start Date*: 2006-01-13
    Sponsor Name:University Hospital Antwerp
    Full Title: Non-invasive monitoring of airway inflammation in asthmatic patients during adaptation of inhaled steroid therapy
    Medical condition: asthma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-001983-31 Sponsor Protocol Number: 1842012 Start Date*: 2012-05-25
    Sponsor Name:Juha Hartikainen
    Full Title:
    Medical condition: Coronary artery by-pass surgery patients
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10011076 Coronary artery atherosclerosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-000458-72 Sponsor Protocol Number: 260411 Start Date*: 2012-05-25
    Sponsor Name:Juha Hartikainen
    Full Title:
    Medical condition: Coronary artery by-pass surgery patients
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10011076 Coronary artery atherosclerosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2021-001528-16 Sponsor Protocol Number: INS1009-202 Start Date*: 2022-05-30
    Sponsor Name:Insmed Incorporated
    Full Title: A Phase 2b, Randomized, Double-Blind, Multicenter, Placebo-Controlled Study to valuate the Efficacy, Safety, and Pharmacokinetics of Treprostinil Palmitil Inhalation Powder in participants with Pu...
    Medical condition: Participants with Pulmonary Arterial Hypertension
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10064911 Pulmonary arterial hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing) IT (Trial now transitioned) AT (Trial now transitioned) DK (Trial now transitioned) BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-002221-35 Sponsor Protocol Number: P2013/PE1 Start Date*: 2014-12-18
    Sponsor Name:Hôpital Universitaire Des Enfants Reine Fabiola
    Full Title: Prospective Randomized Study Comparing the Efficacy and Safety of Pleural Drainage by Video-Assisted Thoracoscopic With Pleural Drain Associated With Urokinase in the Treatment of Parapneumonic Ple...
    Medical condition: Parapneumonic pleural effusion
    Disease: Version SOC Term Classification Code Term Level
    17.0 10021881 - Infections and infestations 10071699 Infectious pleural effusion PT
    17.0 10042613 - Surgical and medical procedures 10014569 Empyema drainage PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004564-55 Sponsor Protocol Number: COSTAL-2013 Start Date*: 2014-03-10
    Sponsor Name:MEDITOP Gyógyszeripari Kft
    Full Title: A randomized, multicenter, double-blind, placebo controlled, parallel study to assess the efficacy and safety of the combined administration of sertraline and lamotrigine in subjects with chronic l...
    Medical condition: Chronic low back pain
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004859 10024891 Low back pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) RO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001427-38 Sponsor Protocol Number: P/2017/337 Start Date*: 2018-07-04
    Sponsor Name:CHU Besançon
    Full Title: Activité et tolérance d’une immunothérapie par avelumab en maintenance après une première ligne de polychimiothérapie contenant un sel de platine chez les patients atteints de carcinome épidermoïde...
    Medical condition: carcinome épidermoïde de verge
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-002390-28 Sponsor Protocol Number: INSPIRE Start Date*: 2022-10-10
    Sponsor Name:Hellenic Institute for the Study of Sepsis
    Full Title: IMMUNOTHERAPY NAVIGATED BY SERUM PRESEPSIN FOR INFECTIONS OF THE RESPIRATORY TRACT: THE INSPIRE DOUBLE-BLIND, RANDOMIZED, PHASE IIa EXPLORATORY TRIAL
    Medical condition: community-acquired pneumonia, hospital-acquired pneumonia
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004862 10010120 Community acquired pneumonia LLT
    20.0 100000004862 10076918 Hospital acquired pneumonia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-000642-16 Sponsor Protocol Number: H4COVID Start Date*: 2022-03-04
    Sponsor Name:Hellenic Institute for the Study of Sepsis
    Full Title: Hydrogen sulfate guided therapy with STS for COVID-19 patients in need of critical care: The H4COVID open-label, randomized, triple-arm trial
    Medical condition: Assessment of clinical improvement of critically ill patients with confirmed Covid-19 by administering of sodium thiosulfate
    Disease: Version SOC Term Classification Code Term Level
    23.0 10021881 - Infections and infestations 10084268 COVID-19 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001302-15 Sponsor Protocol Number: BIO-CT-001 Start Date*: 2019-09-13
    Sponsor Name:BIOKOSMOS S.A.
    Full Title: Phase III study of Positron/Computerized Tomography (PETCT) with F-18-PSMA-1007 versus F-18-Fluorocholine to compare the detection rate of prostate cancer lesions in patients with biochemical recur...
    Medical condition: Prostate cancer recurrent
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10036911 Prostate cancer recurrent PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-003611-62 Sponsor Protocol Number: LIB003-003 Start Date*: 2020-03-20
    Sponsor Name:LIB Therapeutics, LLC
    Full Title: Randomized, Open-Label, Cross-Over, Phase 3 Study to Evaluate the Efficacy and Safety of LIB003 with Evolocumab in Homozygous Familial Hypercholesterolemia Patients on Stable Lipid-Lowering Therapy.
    Medical condition: Homozygous Familial Hypercholesterolemia
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10057080 Homozygous familial hypercholesterolemia LLT
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005989-38 Sponsor Protocol Number: Start Date*: 2012-11-01
    Sponsor Name:Norwegian University of Science and Technology
    Full Title: A SAFETY AND EFFICACY STUDY OF ADDING LOW DOSE PEGYLATED IFN-ΑLPHA 2B TO STANDARD DOSE DASATINIB IN PATIENTS WITH NEWLY DIAGNOSED CHRONIC PHASE CHRONIC MYELOID LEUKEMIA
    Medical condition: Chronic myeloid leukemia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed) FI (Completed) SE (Ongoing) DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-001264-38 Sponsor Protocol Number: MOU-2017-01 Start Date*: 2017-10-16
    Sponsor Name:Masaryk Memorial Cancer Institute
    Full Title: Sequential FDG-PET and Plasma/Tissue miRNA as a Biomarkers of Preoperative Treatment Strategy in Locally Advanced Oesophago-Gastric Cancer
    Medical condition: locally advanced resectable oesophago-gastric adenocarcinoma (Siewert I – III) with T3N0, T4N0, T2 – T4N+, stage Ib – IIIc
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) SK (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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